(Q36629205)

English

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

scientific article published on 12 July 2007

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma (English)

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Europe PubMed Central

15 August 2017

B-cell lymphoma

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based on heuristic

inferred from title

diffuse large B-cell lymphoma

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based on heuristic

inferred from title

20

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19

object named as

E S Jaffe

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Timothy W McKeithan

object named as

T McKeithan

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author name string

J Iqbal

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15 August 2017

T C Greiner

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K Patel

3

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B J Dave

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L Smith

5

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J Ji

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G Wright

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W G Sanger

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D L Pickering

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S Jain

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D E Horsman

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Y Shen

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K Fu

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D D Weisenburger

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C P Hans

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E Campo

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R D Gascoyne

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A Rosenwald

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L Rimsza

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G Ott

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H K Müller-Hermelink

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J M Connors

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J M Vose

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L M Staudt

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W C Chan

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Leukemia/Lymphoma Molecular Profiling Project

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publication date

12 July 2007

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Europe PubMed Central

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21

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2332-2343

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11

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15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404856

0 references

Enhanced detection of TP53 mutations using a GC-clamp in denaturing high performance liquid chromatography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL6 alternative translocation breakpoint cluster region associated with follicular lymphoma grade 3B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Validation of tissue microarray immunohistochemistry staining and interpretation in diffuse large B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

The human BCL6 transgene promotes the development of lymphomas in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Cytogenetic alterations affecting BCL6 are predominantly found in follicular lymphomas grade 3B with a diffuse large B-cell component

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Bcl6 is a transcriptional repressor for the IL-18 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

A short mutational hot spot in the first intron of BCL-6 is associated with increased BCL-6 expression and with longer overall survival in large B-cell lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

The gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

A recurring translocation, t(3;6)(q27;p21), in non-Hodgkin's lymphoma results in replacement of the 5' regulatory region of BCL6 with a novel H4 histone gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Krüppel-like zinc-finger protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

BCL-6 protein is expressed in germinal-center B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

30 September 2017

LAZ3 rearrangements in non-Hodgkin's lymphoma: correlation with histology, immunophenotype, karyotype, and clinical outcome in 217 patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

28 June 2018

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

Rearrangement of the BCL6 locus at 3q27 is an independent poor prognostic factor in nodal diffuse large B-cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

Point mutations of the BCL-6 gene: clinical and prognostic correlation in B-diffuse large cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

Prognostic implications of BCL6 rearrangement in uniformly treated patients with diffuse large B-cell lymphoma--a Nordic Lymphoma Group study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366166

20 September 2018

Identification and characterization of BCL6 translocation partner genes in primary gastric high-grade B-cell lymphoma: heat shock protein 89 alpha is a novel fusion partner gene of BCL6

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and pattern of BCL-6 mutations throughout the spectrum of B-cell neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of the 5' noncoding regulatory region of the BCL-6 gene in non-Hodgkin lymphoma: evidence for recurrent mutations and intraclonal heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonimmunoglobulin (non-Ig)/BCL6 gene fusion in diffuse large B-cell lymphoma results in worse prognosis than Ig/BCL6

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-6 regulates chemokine gene transcription in macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoglobulin (Ig)/BCL6 versus non-Ig/BCL6 gene fusion in diffuse large B-cell lymphoma corresponds to a high- versus low-level expression of BCL6 mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple BCL6 translocation partners in individual cases of gastric lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary mediastinal B-cell lymphoma: hypermutation of the BCL6 gene targets motifs different from those in diffuse large B-cell and follicular lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of the non-Hodgkin's lymphomas: distributions of the major subtypes differ by geographic locations. Non-Hodgkin's Lymphoma Classification Project

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The t(2;3)(q21;q27) translocation in non-Hodgkin's lymphoma displays BCL6 mutations in the 5' regulatory region and chromosomal breakpoints distant from the gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and biological relevance of single-nucleotide polymorphisms and acquired somatic mutations of the BCL6 first intron in follicular lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17625604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.LEU.2404856

1 reference

Europe PubMed Central

15 August 2017

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1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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