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The role of aging upon β cell turnover
scientific article published on March 2013
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
title
The role of aging upon β cell turnover
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
author name string
Jake A Kushner
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
language of work or name
English
0 references
publication date
1 March 2013
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
volume
123
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
page(s)
990-995
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
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Epigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes
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Pancreatic beta cells in very old mice retain capacity for compensatory proliferation
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Free fatty acids block glucose-induced β-cell proliferation in mice by inducing cell cycle inhibitors p16 and p18
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Type 2 diabetes and the aging pancreatic beta cell
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Exendin-4 improves blood glucose control in both young and aging normal non-diabetic mice, possible contribution of beta cell independent effects
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Ongoing beta-cell turnover in adult nonhuman primates is not adaptively increased in streptozotocin-induced diabetes
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Glucose and aging control the quiescence period that follows pancreatic beta cell replication
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Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating
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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
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Cellular origins of beta-cell regeneration: a legacy view of historical controversies
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30 September 2017
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.
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Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
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The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality.
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Adaptive beta-cell proliferation is severely restricted with advanced age.
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30 September 2017
Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice
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Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion
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Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans
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A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
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30 September 2017
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30 September 2017
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
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30 September 2017
p16INK4a induces an age-dependent decline in islet regenerative potential
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Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1
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Comparative study of regenerative potential of beta cells from young and aged donor mice using a novel islet transplantation model
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI64095
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
PMCID
3582123
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
PubMed ID
23454762
1 reference
stated in
Europe PubMed Central
PMCID
3582123
retrieved
15 August 2017
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