(Q36643570)

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Caspase substrates

scientific article published on 3 November 2006

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

Caspase substrates (English)

1 reference

Europe PubMed Central

15 August 2017

author name string

Timmer JC

1

1 reference

Europe PubMed Central

15 August 2017

Salvesen GS

2

1 reference

Europe PubMed Central

15 August 2017

publication date

3 November 2006

1 reference

Europe PubMed Central

15 August 2017

Cell Death & Differentiation

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Europe PubMed Central

15 August 2017

14

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Europe PubMed Central

15 August 2017

66-72

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Europe PubMed Central

15 August 2017

1

1 reference

Europe PubMed Central

15 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402059

0 references

Caspases - controlling intracellular signals by protease zymogen activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

21 January 2018

Human ICE/CED-3 protease nomenclature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Activity-based probes that target diverse cysteine protease families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Human caspase-7 activity and regulation by its N-terminal peptide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel Apaf-1-independent putative caspase-2 activation complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Protease degradomics: a new challenge for proteomics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

The pro-region of the Kex2 endoprotease of Saccharomyces cerevisiae is removed by self-processing.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Many cuts to ruin: a comprehensive update of caspase substrates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of XIAP-mediated inhibition of caspase-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Solution structure of BID, an intracellular amplifier of apoptotic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the heterodimeric complex between CAD domains of CAD and ICAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for the activation of human procaspase-7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular recognition. Conformational analysis of limited proteolytic sites and serine proteinase protein inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

PoPS: a computational tool for modeling and predicting protease specificity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Toward computer-based cleavage site prediction of cysteine endopeptidases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

CaSPredictor: a new computer-based tool for caspase substrate prediction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Prediction of caspase cleavage sites using Bayesian bio-basis function neural networks.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Protease activation during apoptosis: death by a thousand cuts?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein structures that shape caspase activity, specificity, activation and inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro-caspase-3 is a major physiologic target of caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspases induce cytochrome c release from mitochondria by activating cytosolic factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of poly(ADP-ribose) polymerase by interleukin-1 beta converting enzyme and its homologs TX and Nedd-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-9 can be activated without proteolytic processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Depletion of wild-type huntingtin in mouse models of neurologic diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: implications for synaptic plasticity and excitotoxic neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402059

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CDD.4402059

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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