(Q40330849)

19 September 2017

title

Activity-based probes that target diverse cysteine protease families (English)

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19 September 2017

9

Matthew Bogyo

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19 September 2017

Daisuke Kato

1

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19 September 2017

Kelly M Boatright

2

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19 September 2017

Alicia B Berger

3

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19 September 2017

Tamim Nazif

4

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19 September 2017

Galia Blum

5

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19 September 2017

Ciara Ryan

6

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19 September 2017

Kareem A H Chehade

7

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19 September 2017

Guy S Salvesen

8

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19 September 2017

publication date

24 May 2005

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19 September 2017

published in

Nature Chemical Biology

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19 September 2017

volume

1

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19 September 2017

issue

1

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19 September 2017

page(s)

33-38

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Chemical strategies for activity-based proteomics

19 September 2017

cites work

1 reference

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Chemical proteomics and its application to drug discovery

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8

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7 January 2021

Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase.

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Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones

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7 January 2021

Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases

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7 January 2021

Irreversible inhibitors of serine, cysteine, and threonine proteases

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7 January 2021

Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones

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Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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Synthesis of a Diverse Library of Mechanism-Based Cysteine Protease Inhibitors

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Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases

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7 January 2021

Modification of S1 subsite specificity in the cysteine protease cathepsin B.

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7 January 2021

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

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7 January 2021

Activation of human prolegumain by cleavage at a C-terminal asparagine residue

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7 January 2021

Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo

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7 January 2021

Autocatalytic activation of human legumain at aspartic acid residues

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7 January 2021

Mechanisms of caspase activation

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https://api.crossref.org/works/10.1038%2FNCHEMBIO707

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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7 January 2021

Human caspase-7 activity and regulation by its N-terminal peptide.

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https://api.crossref.org/works/10.1038%2FNCHEMBIO707

7 January 2021

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

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7 January 2021

Crystallization and preliminary X-ray study of the cathepsin B complexed with CA074, a selective inhibitor

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7 January 2021

Caspases: preparation and characterization

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7 January 2021

Pro-caspase-3 is a major physiologic target of caspase-8.

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7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO707

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Dimensions Publication ID

19 September 2017

1016969866

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