(Q36646264)

15 August 2017

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title

On the hypothesis that the failing heart is energy starved: lessons learned from the metabolism of ATP and creatine (English)

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15 August 2017

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Joanne S Ingwall

1

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15 August 2017

language of work or name

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1 December 2006

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Current Hypertension Reports

15 August 2017

published in

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15 August 2017

volume

8

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15 August 2017

issue

6

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15 August 2017

page(s)

457-464

1 reference

https://scigraph.springernature.com/pub.10.1007/s11906-006-0023-x

15 August 2017

exact match

0 references

cites work

Enalapril treatment increases cardiac performance and energy reserve via the creatine kinase reaction in myocardium of Syrian myopathic hamsters with advanced heart failure.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11906-006-0023-X

Creatine transporter activity and content in the rat heart supplemented by and depleted of creatine

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11906-006-0023-X

Downregulation of the Na(+)-creatine cotransporter in failing human myocardium and in experimental heart failure.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11906-006-0023-X

Biochemical and clinical characteristics of creatine deficiency syndromes.

21 January 2018

1 reference

12 December 2020

Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-N-methyltransferase-knockout mice

1 reference

12 December 2020

Metabolic energetics and genetics in the heart

1 reference

12 December 2020

Energy metabolism in heart failure

1 reference

12 December 2020

The creatine kinase system in normal and diseased human myocardium

1 reference

12 December 2020

Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3.

1 reference

12 December 2020

Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR.

1 reference

12 December 2020

The fall in creatine levels and creatine kinase isozyme changes in the failing heart are reversible: complex post-transcriptional regulation of the components of the CK system

1 reference

12 December 2020

Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure

1 reference

12 December 2020

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

1 reference

12 December 2020

A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts

1 reference

12 December 2020

Energetics of the failing heart: new insights using genetic modification in the mouse.

1 reference

12 December 2020

Is the failing heart energy starved? On using chemical energy to support cardiac function

1 reference

12 December 2020

Myocardial substrate metabolism in the normal and failing heart

1 reference

12 December 2020

Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice

1 reference

12 December 2020

Mitochondrial energy metabolism in heart failure: a question of balance

1 reference

12 December 2020

Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

1 reference

12 December 2020

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner

1 reference

12 December 2020

Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

12 December 2020

Mitochondrial oxidative stress and heart failure

1 reference

12 December 2020

AMP-activated protein kinase: a key stress signaling pathway in the heart

1 reference

12 December 2020

Transgenesis and cardiac energetics: new insights into cardiac metabolism

1 reference

12 December 2020

Role of creatine kinase in cardiac excitation-contraction coupling: studies in creatine kinase-deficient mice

1 reference

12 December 2020

Subcellular creatine kinase alterations. Implications in heart failure

1 reference

12 December 2020

Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity

1 reference

12 December 2020

Nuclear receptor signaling and cardiac energetics

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

1 reference

12 December 2020

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle

1 reference

12 December 2020

Cyclosporin A inhibits creatine uptake by altering surface expression of the creatine transporter

1 reference

12 December 2020

Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization

1 reference

12 December 2020

Regional absence of mitochondria causing energy depletion in the myocardium of muscle LIM protein knockout mice

1 reference

12 December 2020

Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?

1 reference

12 December 2020

Cardiac fatty acid metabolism is preserved in the compensated hypertrophic rat heart

1 reference

12 December 2020

Progressive loss of myocardial ATP due to a loss of total purines during the development of heart failure in dogs: a compensatory role for the parallel loss of creatine

1 reference

12 December 2020

Creatine kinase system in failing and nonfailing human myocardium

1 reference

12 December 2020

Decreased energy reserve in an animal model of dilated cardiomyopathy. Relationship to contractile performance

1 reference

12 December 2020

A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

1 reference

12 December 2020

Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart

1 reference

12 December 2020

Depletion of Energy Reserve via the Creatine Kinase Reaction During the Evolution of Heart Failure in Cardiomyopathic Hamsters

1 reference

12 December 2020

Impaired cardiac energetics in mice lacking muscle-specific isoenzymes of creatine kinase

1 reference

12 December 2020

Mechanisms of creatine depletion in chronically failing rat heart

1 reference

12 December 2020

Creatine synthesis and transport during rat embryogenesis: spatiotemporal expression of AGAT, GAMT and CT1.

1 reference

12 December 2020

Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth

1 reference

12 December 2020

10.1007/S11906-006-0023-X

Identifiers

DOI

1 reference

release_htpo2b3ah5hw3gbgbjn5yo6sqm

15 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/htpo2b3ah5hw3gbgbjn5yo6sqm

24 November 2022

mapped directly with Wikidata item

1 reference