(Q36646357)

15 August 2017

Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase (English)

1 reference

15 August 2017

Kelly M Bailey

1

1 reference

15 August 2017

Jun Liu

series ordinal

2

1 reference

15 August 2017

language of work or name

English

0 references

publication date

10 March 2008

1 reference

Journal of Biological Chemistry

15 August 2017

1 reference

15 August 2017

283

1 reference

15 August 2017

20

1 reference

15 August 2017

13714-13724

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2376249/fullTextXML

inferred from PubMed Central ID database lookup

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Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases

30 September 2017

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30 September 2017

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A proximal activator of transcription in epithelial-mesenchymal transition

30 September 2017

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Identification of a novel domain at the N terminus of caveolin-1 that controls rear polarization of the protein and caveolae formation

30 September 2017

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Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.

30 September 2017

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30 September 2017

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Epithelial-to-mesenchymal transition confers resistance to apoptosis in three murine mammary epithelial cell lines

30 September 2017

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Collagen type I induces disruption of E-cadherin-mediated cell-cell contacts and promotes proliferation of pancreatic carcinoma cells

30 September 2017

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Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells

30 September 2017

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30 September 2017

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E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function

30 September 2017

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TGF-beta and epithelial-to-mesenchymal transitions

30 September 2017

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

30 September 2017

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Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?

30 September 2017

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The Snail genes as inducers of cell movement and survival: implications in development and cancer.

30 September 2017

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Caveolin-1 in oncogenic transformation, cancer, and metastasis

30 September 2017

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30 September 2017

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Loss of caveolin-1 polarity impedes endothelial cell polarization and directional movement

30 September 2017

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Caveolin-1 is required for vascular endothelial growth factor-triggered multiple myeloma cell migration and is targeted by bortezomib

30 September 2017

1 reference

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Transcriptional regulation of cadherins during development and carcinogenesis.

30 September 2017

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Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer

30 September 2017

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Epithelial-mesenchymal transitions in development and pathologies

30 September 2017

1 reference

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Differential caveolin-1 polarization in endothelial cells during migration in two and three dimensions

30 September 2017

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FAK regulates biological processes important for the pathogenesis of cancer

30 September 2017

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Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation

30 September 2017

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Focal adhesion kinase: the first ten years

30 September 2017

1 reference

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Differential regulation of cell motility and invasion by FAK

30 September 2017

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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

30 September 2017

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Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

30 September 2017

1 reference

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Upregulation of caveolin in multidrug resistant cancer cells: functional implications

30 September 2017

1 reference

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Caveolin-1, a putative tumour suppressor gene

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

30 September 2017

https://api.crossref.org/works/10.1074%2FJBC.M709329200

Hybrids of pluripotent and nullipotent human embryonal carcinoma cells: partial retention of a pluripotent phenotype

21 January 2018

1 reference

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Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Caveolins, liquid-ordered domains, and signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Elevated expression of caveolin is associated with prostate and breast cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Peptide growth factors are multifunctional

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Caveolin, a protein component of caveolae membrane coats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Invasion activating caveolin-1 mutation in human scirrhous breast cancers.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Cell-surface antigens of a clonal human embryonal carcinoma cell line: morphological and antigenic differentiation in culture.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TY

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Cyclosporine induces cancer progression by a cell-autonomous mechanism.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376249

Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18332144

12 December 2020

inferred from PubMed ID database lookup

Caveolin-1 expression is associated with high-grade bladder cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18332144

12 December 2020

inferred from PubMed ID database lookup

Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18332144

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M709329200

1 reference

15 August 2017

1 reference

15 August 2017

1 reference