(Q24673170)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Differential regulation of cell motility and invasion by FAK (English)

1 reference

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1 November 2019

0 references

6

1 reference

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1 November 2019

Erguang Li

8

1 reference

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1 November 2019

author name string

Datsun A Hsia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Satyajit K Mitra

2

1 reference

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1 November 2019

Christof R Hauck

3

1 reference

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1 November 2019

Daniel N Streblow

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Jay A Nelson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Shuang Huang

7

1 reference

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1 November 2019

Glen R Nemerow

9

1 reference

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1 November 2019

Jay Leng

10

1 reference

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1 November 2019

Kathryn S R Spencer

11

1 reference

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1 November 2019

David A Cheresh

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

David D Schlaepfer

13

1 reference

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1 November 2019

language of work or name

English

0 references

publication date

1 March 2003

1 reference

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1 November 2019

number of pages

15

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

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1 November 2019

volume

160

1 reference

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1 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

753-767

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 November 2019

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2173366/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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7 April 2017

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Regulation of cell motility by mitogen-activated protein kinase

7 April 2017

1 reference

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Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

7 April 2017

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A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

7 April 2017

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7 April 2017

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Biochemical signals and biological responses elicited by the focal adhesion kinase

7 April 2017

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Plasma membrane-associated pY397FAK is a marker of cytotrophoblast invasion in vivo and in vitro

7 April 2017

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7 April 2017

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FAK integrates growth-factor and integrin signals to promote cell migration

7 April 2017

1 reference

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Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry

7 April 2017

1 reference

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Matrix metalloproteinases: multifunctional contributors to tumor progression

7 April 2017

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Matrix metalloproteinases

7 April 2017

1 reference

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Signaling through focal adhesion kinase

7 April 2017

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Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate

7 April 2017

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

7 April 2017

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Rho GTPases and their effector proteins

7 April 2017

1 reference

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

7 April 2017

1 reference

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Role of integrins in cell invasion and migration

7 April 2017

1 reference

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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

28 September 2017

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Src kinase contributes to the metastatic spread of carcinoma cells

28 September 2017

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SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading

28 September 2017

1 reference

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v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion

28 September 2017

1 reference

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Transformation of chicken embryo fibroblasts by v-src uncouples beta1 integrin-mediated outside-in but not inside-out signaling

28 September 2017

1 reference

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Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells

28 September 2017

1 reference

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Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells

28 September 2017

1 reference

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The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase

28 September 2017

1 reference

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Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

28 September 2017

1 reference

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Role of Src expression and activation in human cancer

28 September 2017

1 reference

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Transcriptional regulation of cell invasion: AP-1 regulation of a multigenic invasion programme

28 September 2017

1 reference

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Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

28 September 2017

1 reference

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Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-activated protein kinase activity

28 September 2017

1 reference

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Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

28 September 2017

1 reference

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Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

28 September 2017

1 reference

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Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

The v-Src SH3 domain binds phosphatidylinositol 3'-kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Motility and invasion are differentially modulated by Rho family GTPases

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Augmentation of metalloproteinase (gelatinase) activity secreted from Rous sarcoma virus-infected cells correlates with transforming activity of src.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v-Src, but is not a critical determinant of v-Src transformation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173366

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

28 November 2018

1 reference

12 December 2020

Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells

1 reference

12 December 2020

Focal adhesion kinase and its potential involvement in tumor invasion and metastasis

1 reference

12 December 2020

Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes

1 reference

12 December 2020

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

1 reference

12 December 2020

Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200212114

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12615911%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

12615911

2 references