(Q36646501)

English

Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.

scientific article published on 8 February 2016

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scholarly article

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7 March 2020

Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7 (English)

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7 March 2020

Plasmodium falciparum

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Hanafy M Ismail

1

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7 March 2020

Matthew Phanchana

3

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7 March 2020

Sitthivut Charoensutthivarakul

4

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7 March 2020

Michael H-L Wong

5

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7 March 2020

Janet Hemingway

6

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7 March 2020

Giancarlo Biagini

7

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7 March 2020

9

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7 March 2020

author name string

Victoria Barton

2

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7 March 2020

Paul M O'Neill

8

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7 March 2020

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8 February 2016

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7 March 2020

Proceedings of the National Academy of Sciences of the United States of America

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7 March 2020

113

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7 March 2020

8

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7 March 2020

2080-2085

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7 March 2020

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

1 reference

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Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

1 reference

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Drug resistance genomics of the antimalarial drug artemisinin

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A chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistry

1 reference

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Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus

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Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites

1 reference

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A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

1 reference

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Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential

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30 September 2017

STITCH 4: integration of protein-chemical interactions with user data

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Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

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30 September 2017

A travel guide to Cytoscape plugins

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30 September 2017

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

1 reference

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30 September 2017

Molecular chaperones in protein folding and proteostasis

1 reference

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30 September 2017

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Purine and pyrimidine pathways as targets in Plasmodium falciparum

1 reference

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30 September 2017

Protein S-glutathionylation in malaria parasites

1 reference

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30 September 2017

Central carbon metabolism of Plasmodium parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase

1 reference

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30 September 2017

The molecular mechanism of action of artemisinin--the debate continues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Plasmodium food vacuole plasmepsins are activated by falcipains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Copper-free click chemistry for dynamic in vivo imaging

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs.

1 reference

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30 September 2017

Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Malarial (Plasmodium falciparum) dihydrofolate reductase-thymidylate synthase: structural basis for antifolate resistance and development of effective inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Artemisinins: mechanisms of action and potential for resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Profiling enzyme activities in vivo using click chemistry methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4776496

30 September 2017

Artemisinins target the SERCA of Plasmodium falciparum

1 reference

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30 September 2017

Genome sequence of the human malaria parasite Plasmodium falciparum

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30 September 2017

Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

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Vacuolar H(+)-ATPase localized in plasma membranes of malaria parasite cells, Plasmodium falciparum, is involved in regional acidification of parasitized erythrocytes

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Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite

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30 September 2017

Reaction of antimalarial endoperoxides with specific parasite proteins

1 reference

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30 September 2017

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum

1 reference

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30 September 2017

Oxidative stress and the redox status of malaria-infected erythrocytes

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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30 September 2017

Human malaria parasites in continuous culture

1 reference

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Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

1 reference

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1 reference

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The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials

1 reference

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Activated oxygen mediates the antimalarial activity of qinghaosu.

1 reference

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Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action

1 reference

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28 June 2018

Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action

1 reference

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Alkylating ability of artemisinin after Cu(I)-induced activation.

1 reference

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20 September 2018

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1 reference

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20 September 2018

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

1 reference

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Malaria: to kill a parasite

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20 September 2018

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20 September 2018

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1 reference

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20 September 2018

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1 reference

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20 September 2018

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1 reference

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20 September 2018

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1 reference

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20 September 2018

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21 January 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/26858419

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1600459113

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26858419%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

2016PNAS..113.2080I

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1 reference

Europe PubMed Central

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7 March 2020

1 reference

Europe PubMed Central

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7 March 2020

ResearchGate publication ID

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