(Q36647385)

English

A natural inactivating mutation in the CovS component of the CovRS regulatory operon in a pattern D Streptococcal pyogenes strain influences virulence-associated genes

scientific article published on 13 January 2013

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

A natural inactivating mutation in the CovS component of the CovRS regulatory operon in a pattern D Streptococcal pyogenes strain influences virulence-associated genes (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Victoria Ploplis

8

object named as

Victoria A Ploplis

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Francis J Castellino

9

object named as

Francis J Castellino

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Zhong Liang

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Yueling Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Garima Agrahari

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Vishwanatha Chandrahas

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Kristofor Glinton

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Deborah L Donahue

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Rashna D Balsara

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

0 references

publication date

13 January 2013

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

288

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

6561-6573

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Characterization of streptokinases from group A Streptococci reveals a strong functional relationship that supports the coinheritance of plasminogen-binding M protein and cluster 2b streptokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

M protein and hyaluronic acid capsule are essential for in vivo selection of covRS mutations characteristic of invasive serotype M1T1 group A Streptococcus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The streptococcal M protein: a highly versatile molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

M protein-mediated plasminogen binding is essential for the virulence of an invasive Streptococcus pyogenes isolate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

RivR and the small RNA RivX: the missing links between the CovR regulatory cascade and the Mga regulon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The Mga virulence regulon: infection where the grass is greener.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Defining the Mga regulon: Comparative transcriptome analysis reveals both direct and indirect regulation by Mga in the group A streptococcus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The global burden of group A streptococcal diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The M protein is dispensable for maturation of streptococcal cysteine protease SpeB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Plasminogen binding by group A streptococcal isolates from a region of hyperendemicity for streptococcal skin infection and a high incidence of invasive infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Natural selection and evolution of streptococcal virulence genes involved in tissue-specific adaptations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Virulence factor regulation and regulatory networks in Streptococcus pyogenes and their impact on pathogen-host interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Molecular basis of group A streptococcal virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The CsrR/CsrS two-component system of group A Streptococcus responds to environmental Mg2+

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Bacterial plasminogen activators and receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Complete genome sequence of an M1 strain of Streptococcus pyogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Multilocus sequence typing of Streptococcus pyogenes and the relationships between emm type and clone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

An internal histidine residue from the bacterial surface protein, PAM, mediates its binding to the kringle-2 domain of human plasminogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The SpeB virulence factor of Streptococcus pyogenes, a multifunctional secreted and cell surface molecule with strepadhesin, laminin-binding and cysteine protease activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

A two-component regulatory system, CsrR-CsrS, represses expression of three Streptococcus pyogenes virulence factors, hyaluronic acid capsule, streptolysin S, and pyrogenic exotoxin B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Selective distribution of a high-affinity plasminogen-binding site among group A streptococci associated with impetigo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

A response regulator that represses transcription of several virulence operons in the group A streptococcus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Expression of human plasminogen in Drosophila Schneider S2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Kringle 2 mediates high affinity binding of plasminogen to an internal sequence in streptococcal surface protein PAM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Hyaluronic acid capsule and the role of streptococcal entry into keratinocytes in invasive skin infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Genetic correlates of throat and skin isolates of group A streptococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

PAM, a novel plasminogen-binding protein from Streptococcus pyogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Streptokinase activates plasminogen bound to human group C and G streptococci through M-like proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

The group A streptococcal virR49 gene controls expression of four structural vir regulon genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Specific binding of the activator Mga to promoter sequences of the emm and scpA genes in the group A streptococcus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Coregulation of type 12 M protein and streptococcal C5a peptidase genes in group A streptococci: evidence for a virulence regulon controlled by the virR locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Architecture of the vir regulons of group A streptococci parallels opacity factor phenotype and M protein class

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

Clonal basis for resurgence of serious Streptococcus pyogenes disease in the 1980s

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

30 September 2017

CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

28 June 2018

Regulation of streptokinase expression by CovR/S in Streptococcus pyogenes: CovR acts through a single high-affinity binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

28 June 2018

Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

28 June 2018

ECM and cell surface proteolysis: regulating cellular ecology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

28 June 2018

The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Unraveling the regulatory network in Streptococcus pyogenes: the global response regulator CovR represses rivR directly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Mouse skin passage of Streptococcus pyogenes results in increased streptokinase expression and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Comparative analysis of prototype two-component systems with either bifunctional or monofunctional sensors: differences in molecular structure and physiological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Identification of binding sites for the group A streptococcal global regulator CovR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Characterization of a two-component system in Streptococcus pyogenes which is involved in regulation of hyaluronic acid production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Many group A streptococcal strains express two different immunoglobulin-binding proteins, encoded by closely linked genes: characterization of the proteins expressed by four strains of different M-type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585089

20 September 2018

Identifying and genotyping transgene integration loci

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen is a critical host pathogenicity factor for group A streptococcal infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A secreted receptor related to M1 protein of Streptococcus pyogenes binds to fibrinogen, IgG, and albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three different types of organization of the vir regulon in group A streptococci

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vir typing: a long-PCR typing method for group A streptococci

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plasmin-binding protein Plr of group A streptococci is identified as glyceraldehyde-3-phosphate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular co-operation between protein PAM and streptokinase for plasmin acquisition by Streptococcus pyogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trigger for group A streptococcal M1T1 invasive disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Maintenance of High Affinity Plasminogen Binding by Group A Streptococcal Plasminogen-binding M-like Protein Is Mediated by Arginine and Histidine Residues within the a1 and a2 Repeat Domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.442657

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

release_f6ta3xes6bh5xe5uodbithva4e

1 reference

https://api.fatcat.wiki/v0/release/f6ta3xes6bh5xe5uodbithva4e

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36647385&oldid=1840142015"