(Q36647425)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

review article

1 reference

title

Mitochondrial DNA damage and the aging process: facts and imaginations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Wolfram S. Kunz

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Rudolf J Wiesner

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

publication date

1 December 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

published in

Free Radical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

1284-1294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17090418%20AND%20SRC:MED&resulttype=core&format=json

Aging: a theory based on free radical and radiation chemistry

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Biogenesis of mitochondria

21 January 2018

1 reference

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Inhibition of mitochondrial protein synthesis promotes autonomous regulation of mtDNA expression and generation of a new mitochondrial RNA species

21 January 2018

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Replication of animal mitochondrial DNA.

21 January 2018

1 reference

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Mitochondrial DNA maintenance in vertebrates

21 January 2018

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Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Reconstitution of a minimal mtDNA replisome in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Precise localization of the origin of replication in a physical map of HeLa cell mitochondrial DNA and isolation of a small fragment that contains it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Evidence for a two membrane–spanning autonomous mitochondrial DNA replisome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Composition and dynamics of human mitochondrial nucleoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

The organization and inheritance of the mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Purification and characterization of human mitochondrial transcription factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Manipulation of mitochondrial DNA gene expression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mechanism of mammalian mitochondrial DNA replication: import of mitochondrial transcription factor A into isolated mitochondria stimulates 7S DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Import of mitochondrial transcription factor A (TFAM) into rat liver mitochondria stimulates transcription of mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Human mitochondrial DNA is packaged with TFAM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

In organello footprint analysis of human mitochondrial DNA: human mitochondrial transcription factor A interactions at the origin of replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Very rare complementation between mitochondria carrying different mitochondrial DNA mutations points to intrinsic genetic autonomy of the organelles in cultured human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial dynamics and aging: Mitochondrial interaction preventing individuals from expression of respiratory deficiency caused by mutant mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Stereoselective excision of thymine glycol from oxidatively damaged DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Efficient repair of abasic sites in DNA by mitochondrial enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial DNA ligase III function is independent of Xrcc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mammalian mitochondria possess homologous DNA recombination activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mammalian mitochondrial extracts possess DNA end-binding activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Recombination of human mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Recombination of mitochondrial DNA in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mismatch repair activity in mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Reactive oxygen species and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Role of ubiquinone in the mitochondrial generation of hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Reactive oxygen intermediates in biochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

The potential diagram for oxygen at pH 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Generation of reactive oxygen species by the mitochondrial electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Characterization of superoxide-producing sites in isolated brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Topology of superoxide production from different sites in the mitochondrial electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Characterization of superoxide production sites in isolated rat brain and skeletal muscle mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

The biologic clock: the mitochondria?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Point mutations of the mtDNA control region in normal and neurodegenerative human brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Clonal expansions of mitochondrial genomes: implications for in vivo mutational spectra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial DNA mutations in human colonic crypt stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Age-dependent impairment of mitochondrial function in primate brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Nuclear-recessive mutations of factors involved in mitochondrial translation are responsible for age-related respiration deficiency of human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Decline with age of the respiratory chain activity in human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Development and age-associated differences in electron transport potential and consequences for oxidant generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760600913168