(Q36649559)

English

Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil

scientific article published on 2 February 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

based on heuristic

inferred from title

author name string

Junpu Wang

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Wanming Hu

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Kuansong Wang

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Jun Yu

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Baihua Luo

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Gengqiu Luo

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Weiyuan Wang

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Huiling Wang

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Jinghe Li

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Jifang Wen

10

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

2 February 2016

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

International Journal of Oncology

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

48

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1341-1352

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms

1 reference

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30 September 2017

Upregulation of C-X-C chemokine receptor type 1 expression is associated with late-stage gastric adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Anticancer properties and mechanisms of fucoidan on mouse breast cancer in vitro and in vivo

1 reference

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30 September 2017

Heterodimerization of glycosylated insulin-like growth factor-1 receptors and insulin receptors in cancer cells sensitive to anti-IGF1R antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

The CXCR2 antagonist, SCH-527123, shows antitumor activity and sensitizes cells to oxaliplatin in preclinical colon cancer models

1 reference

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30 September 2017

CXCR4/CXCL12 participate in extravasation of metastasizing breast cancer cells within the liver in a rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer.

1 reference

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30 September 2017

The chemokine system and cancer.

1 reference

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30 September 2017

Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin.

1 reference

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30 September 2017

CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Potential mechanism of interleukin-8 production from lung cancer cells: an involvement of EGF-EGFR-PI3K-Akt-Erk pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

CXC chemokine receptor-1 is expressed by hepatocytes and regulates liver recovery after hepatic ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Gastric cancer: a primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Angiogenesis and lymphangiogenesis of gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Nonresolving inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Chemokines and chemokine receptors: new insights into cancer-related inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Small interfering RNA-mediated CXCR1 or CXCR2 knock-down inhibits melanoma tumor growth and invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Emerging roles of chemokines in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Host CXCR2-dependent regulation of melanoma growth, angiogenesis, and experimental lung metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

The interleukin-8 pathway in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Chemokines in tumor angiogenesis and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Chemokines: novel targets for breast cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Role of chemokines in tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Incidence and mortality of gastric cancer in China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Gastric cancer: epidemiology, pathology and treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

Inflammation and cancer: back to Virchow?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

The molecular biology of leukocyte chemoattractant receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

30 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777600

28 June 2018

Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells

1 reference

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20 September 2018

Inflaming metastasis

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4 December 2018

Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine-rich 61 (CCN1) enhances chemotactic migration, transendothelial cell migration, and intravasation by concomitantly up-regulating chemokine receptor 1 and 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of metastatic lymph node ratio in T3 gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor angiogenesis related to growth pattern and lymph node metastasis in early gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of CXC chemokines in gastric carcinoma: differences in CXCL8 and CXCL1 expression between diffuse and intestinal types of gastric carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26847910

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3892/IJO.2016.3371

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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