(Q238512)

Statements

instance of

type of chemical entity

0 references

subclass of

pyrimidine

0 references

part of

response to 5-fluorouracil

subject has role

reactant

1 reference

stated in

Gene Ontology release 2020-05-02

has use

medication

0 references

chemical structure

Fluorouracil.png
795 × 833; 3 KB

1 reference

imported from Wikimedia project

German Wikipedia

Fluorouracil2DACS.svg
710 × 931; 6 KB

0 references

mass

130.018 dalton

1 reference

stated in

PubChem

PubChem CID

3385

language of work or name

English

title

5-Fluorouracil (English)

retrieved

19 October 2016

chemical formula

C₄H₃FN₂O₂

1 reference

stated in

PubChem

PubChem CID

3385

language of work or name

English

title

5-Fluorouracil (English)

retrieved

19 November 2016

canonical SMILES

C1=C(C(=O)NC(=O)N1)F

1 reference

stated in

PubChem

PubChem CID

3385

language of work or name

English

title

5-Fluorouracil (English)

retrieved

19 November 2016

active ingredient in

Adrucil

1 reference

stated in

RxNorm

RxNorm ID

202632

retrieved

14 February 2018

Carac

1 reference

stated in

RxNorm

RxNorm ID

285133

retrieved

14 February 2018

Tolak

1 reference

stated in

RxNorm

RxNorm ID

1669869

retrieved

14 February 2018

Fluoroplex

1 reference

stated in

RxNorm

RxNorm ID

202633

retrieved

14 February 2018

Efudex

1 reference

stated in

RxNorm

RxNorm ID

224945

retrieved

14 February 2018

World Health Organisation international non-proprietary name

fluorouracil (English)

1 reference

stated in

ChEBI

ChEBI ID

46345

language of work or name

English

title

5-fluorouracil (English)

retrieved

19 October 2016

found in taxon

Carpesium faberi

1 reference

stated in

Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberi

Morus cathayana

1 reference

stated in

2-Arylbenzofuran Derivatives from Morus cathayana

Phakellia fusca

1 reference

stated in

5-Fluorouracil derivatives from the sponge Phakellia fusca.

Eurycoma longifolia

2 references

stated in

Quassinoids from Eurycoma longifolia

stated in

Quassinoids from Eurycoma longifolia

Trichobotrys effusus

1 reference

stated in

Aliphatic phenolic ethers from Trichobotrys effusa

Trichobotrys effusa

1 reference

stated in

Aliphatic phenolic ethers from Trichobotrys effusa

Alpinia roxburghii

1 reference

stated in

Eleven novel diarylheptanoids and two unusual diarylheptanoid derivatives from the seeds of Alpinia blepharocalyx

Alpinia blepharocalyx

1 reference

stated in

Eleven novel diarylheptanoids and two unusual diarylheptanoid derivatives from the seeds of Alpinia blepharocalyx

Cedrus deodara

1 reference

stated in

Tubulin inhibitors from an endophytic fungus isolated from Cedrus deodara

Aspergillus banksianus

1 reference

stated in

Banksialactones and Banksiamarins: Isochromanones and Isocoumarins from an Australian Fungus,Aspergillus banksianus

Taiwanofungus camphoratus

1 reference

stated in

Meroterpenoids from a Medicinal Fungus Antrodia cinnamomea.

Antrodia cinnamomea

1 reference

stated in

Meroterpenoids from a Medicinal Fungus Antrodia cinnamomea.

Daphne genkwa

1 reference

stated in

Daphnane Diterpenoids from Daphne genkwa Inhibit PI3K/Akt/mTOR Signaling and Induce Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells

Patrinia scabra

1 reference

stated in

Cytotoxic iridoids from the roots of Patrinia scabra

Pestalotiopsis neglecta

1 reference

stated in

Benzophenone Compounds, from a Marine-Derived Strain of the Fungus Pestalotiopsis neglecta, Inhibit Proliferation of Pancreatic Cancer Cells by Targeting the MEK/ERK Pathway

Talaromyces stipitatus

1 reference

stated in

Talauxins: Hybrid Phenalenone Dimers from Talaromyces stipitatus

Paramyrothecium roridum

1 reference

stated in

Cytotoxic Trichothecene Macrolides Produced by the Endophytic Myrothecium roridum

Myrothecium roridum

1 reference

stated in

Cytotoxic Trichothecene Macrolides Produced by the Endophytic Myrothecium roridum

Penicillium arenicola

1 reference

stated in

Arenicolins: C-Glycosylated Depsides from Penicillium arenicola

Picrasma quassioides

1 reference

stated in

(±)-Quassidines I and J, two pairs of cytotoxic bis-β-carboline alkaloid enantiomers from Picrasma quassioides

Pseudallescheria boydii

1 reference

stated in

Polyketides from the littoral plant associated fungus Pseudallescheria boydii

Curvularia lunata

1 reference

stated in

Cytotoxic and Antibacterial Eremophilane Sesquiterpenes from the Marine-Derived Fungus Cochliobolus lunatus SCSIO41401

Streptomyces

1 reference

stated in

Strepantibins A-C: Hexokinase II Inhibitors from a Mud Dauber Wasp Associated Streptomyces sp

Penicillium

1 reference

stated in

Penicilindoles A-C, Cytotoxic Indole Diterpenes from the Mangrove-Derived Fungus Eupenicillium sp. HJ002.

medical condition treated

pancreatic cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

head and neck cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

rectum cancer

2 references

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

basal-cell carcinoma

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

stomach cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

keratosis

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

colonic benign neoplasm

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

breast cancer

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

language of work or name

English

retrieved

13 December 2016

actinic keratosis

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

colon cancer

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

tongue squamous cell carcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

head and neck squamous cell carcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

colon adenocarcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

pancreatic adenocarcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

anal squamous cell carcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

invasive ductal carcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

rectum adenocarcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

gastric adenocarcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

gastrointestinal carcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

anal carcinoma

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

skin cancer

1 reference

stated in

Drug Indications Extracted from FAERS

retrieved

2 October 2018

significant drug interaction

rac-warfarin

side effect

Retroperitoneal hemorrhage

1 reference

sourcing circumstances

established

stated in

A reference set of clinically relevant adverse drug-drug interactions

acenocoumarol

side effect

Retroperitoneal hemorrhage

1 reference

sourcing circumstances

established

stated in

A reference set of clinically relevant adverse drug-drug interactions

route of administration

intravenous infusion and defusion

0 references

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category A

1 reference

stated in

LiverTox

retrieved

8 April 2021

reference URL

https://www.ncbi.nlm.nih.gov/books/n/livertox/Fluorouracil

last update

2 February 2018

subject has role

DNA polymerase inhibitors

1 reference

stated in

NDF-RT

NDF-RT ID

N0000146166

retrieved

5 March 2018

antimetabolites

1 reference

stated in

Medical Subject Headings

MeSH descriptor ID

D005472

retrieved

15 March 2018

antineoplastic antimetabolite

1 reference

stated in

Medical Subject Headings

MeSH descriptor ID

D005472

retrieved

15 March 2018

immunosuppressive drug

1 reference

stated in

Medical Subject Headings

MeSH descriptor ID

D005472

retrieved

15 March 2018

essential medicine

0 references

developmental toxicant

start time

1 January 1989

1 reference

stated in

California Proposition 65 list of chemicals

retrieved

26 February 2020

reference URL

https://oehha.ca.gov/chemicals/fluorouracil

MCN code

2933.59.23

0 references

Commons category

5-Fluorouracil

0 references

Identifiers