(Q36652599)

15 August 2017

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title

Antimalarial drug therapy: the role of parasite biology and drug resistance (English)

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15 August 2017

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Johanna P Daily

1

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15 August 2017

publication date

1 December 2006

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The Journal of Clinical Pharmacology

15 August 2017

published in

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15 August 2017

volume

46

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15 August 2017

issue

12

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15 August 2017

page(s)

1487-1497

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Discovery of gene function by expression profiling of the malaria parasite life cycle

15 August 2017

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The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum

21 January 2018

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A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum

21 January 2018

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The global distribution and population at risk of malaria: past, present, and future

21 January 2018

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Parasite immune escape: new views into host-parasite interactions

21 January 2018

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Clinical features and outcome of severe malaria in Gambian children

21 January 2018

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Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment

21 January 2018

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Impact of asymptomatic malaria parasitaemia on cognitive function and school achievement of schoolchildren in the Yemen Republic

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270006294276

A review of the quality of randomized clinical trials of adjunctive therapy for the treatment of cerebral malaria

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270006294276

Exchange transfusion as an adjunct therapy in severe Plasmodium falciparum malaria: a meta-analysis

21 January 2018

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The war between the malaria parasite and the immune system: immunity, immunoregulation and immunopathology

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270006294276

Dexamethasone proves deleterious in cerebral malaria. A double-blind trial in 100 comatose patients

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270006294276

High-dose dexamethasone in quinine-treated patients with cerebral malaria: a double-blind, placebo-controlled trial

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270006294276

Artemisinins target the SERCA of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Chloroquine increases Plasmodium falciparum gametocytogenesis in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half-life

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270006294276

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Quinoline antimalarials: mechanisms of action and resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Mode of action and mechanisms of resistance for antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Theories on malarial pigment formation and quinoline action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

A molecular marker for chloroquine-resistant falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Polymorphisms in the Plasmodium falciparum pfcrt and pfmdr-1 genes and clinical response to chloroquine in Kampala, Uganda

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Prevalence of Plasmodium falciparum pfcrt polymorphisms and in vitro chloroquine sensitivity in Senegal

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

pfcrt polymorphism and chloroquine resistance in Plasmodium falciparum strains isolated in Cambodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Multiple transporters associated with malaria parasite responses to chloroquine and quinine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Withdrawing antimalarial drugs: impact on parasite resistance and implications for malaria treatment policies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

The disposition of amodiaquine in Zambians and Nigerians with malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Systematic review of amodiaquine treatment in uncomplicated malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Amodiaquine as the first-line treatment of malaria in Yaoundé, Cameroon: presumptive evidence from activity in vitro and cross-resistance patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Disposition of oral quinine in acute falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Contribution of the pfmdr1 gene to antimalarial drug-resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Predictors of mefloquine treatment failure: a prospective study of 1590 patients with uncomplicated falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Tolerability of malaria chemoprophylaxis in non-immune travellers to sub-Saharan Africa: multicentre, randomised, double blind, four arm study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Effect of primaquine on gametocytes of Plasmodium falciparum in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Primaquine therapy for malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Randomized trial of 3-dose regimens of tafenoquine (WR238605) versus low-dose primaquine for preventing Plasmodium vivax malaria relapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Intercontinental spread of pyrimethamine-resistant malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Malarone treatment failure not associated with previously described mutations in the cytochrome b gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Evaluation of atovaquone in the treatment of patients with uncomplicated Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Efficacy of rectal artesunate compared with parenteral quinine in initial treatment of moderately severe malaria in African children and adults: a randomised study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Dose-dependent brainstem neuropathology following repeated arteether administration in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Artesunate combinations for treatment of malaria: meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Clinical pharmacokinetics and pharmacodynamics of artemisinin and derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

A meta-analysis using individual patient data of trials comparing artemether with quinine in the treatment of severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Stage-specific gametocytocidal effect in vitro of the antimalaria drug qinghaosu on Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Drug resistant Plasmodium vivax malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Artemisinin or chloroquine for blood stage Plasmodium vivax malaria in Vietnam

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Randomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Mefloquine is highly efficacious against chloroquine-resistant Plasmodium vivax malaria and Plasmodium falciparum malaria in Papua, Indonesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Atovaquone and proguanil hydrochloride followed by primaquine for treatment of Plasmodium vivax malaria in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Antimalarial activities of novel synthetic cysteine protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Terpenes arrest parasite development and inhibit biosynthesis of isoprenoids in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Fractions of an antimalarial neem-leaf extract have activities superior to chloroquine, and are gametocytocidal

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

The price of innovation: new estimates of drug development costs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Gametocytaemia in Senegalese children with uncomplicated falciparum malaria treated with chloroquine, amodiaquine or sulfadoxine + pyrimethamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270006294276

21 January 2018

Identifiers

DOI

10.1177/0091270006294276

1 reference

15 August 2017

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