(Q36653990)

15 August 2017

Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth (English)

1 reference

gastrointestinal stromal tumor

15 August 2017

1 reference

1 reference

13

Matt van de Rijn

1 reference

15 August 2017

12

Irving L Weissman

1 reference

15 August 2017

5

Jens-Peter Volkmer

1 reference

Humberto Contreras-Trujillo

15 August 2017

8

object named as

Humberto Contreras-Trujillo

1 reference

15 August 2017

3

Kipp Weiskopf

1 reference

15 August 2017

1

Badreddin Edris

1 reference

15 August 2017

4

Anne K Volkmer

1 reference

15 August 2017

6

Thomas Mühlenberg

1 reference

15 August 2017

Stephen B Willingham

2

1 reference

15 August 2017

Kelli D Montgomery

7

1 reference

15 August 2017

Agnieszka Czechowicz

9

1 reference

15 August 2017

Jonathan A Fletcher

10

1 reference

15 August 2017

Robert B West

11

1 reference

15 August 2017

language of work or name

English

0 references

publication date

4 February 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

110

1 reference

15 August 2017

9

1 reference

15 August 2017

3501-3506

1 reference

Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Gastrointestinal stromal tumours: origin and molecular oncology.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Monoclonal antibodies: versatile platforms for cancer immunotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

KIT mutations are common in testicular seminomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

The stem cell factor-c-kit system and mast cells in human pancreatic cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Clinical management of gastrointestinal stromal tumors: before and after STI-571.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Expression of stem cell factor and c-kit in human neuroblastoma. The Children's Cancer Group

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Epitope mapping and functional studies with three monoclonal antibodies to the c-kit receptor tyrosine kinase, YB5.B8, 17F11, and SR-1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Isolation and characterization of a monoclonal antibody that recognizes the human c-kit receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587280

Modulation of p145c-kit function in cells of patients with acute myeloblastic leukemia

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23382202

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical efficacy and safety of sunitinib after imatinib failure in Japanese patients with gastrointestinal stromal tumor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23382202

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased gene copy number of KIT and VEGFR2 at 4q12 in primary breast cancer is related to an aggressive phenotype and impaired prognosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23382202

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1222893110

1 reference

15 August 2017

0 references

1 reference

15 August 2017

1 reference