(Q36660533)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Phase II trial of single-agent foretinib (GSK1363089) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

metastatic squamous cell carcinoma

11 February 2020

main subject

phase II clinical trial

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

George R Blumenschein

6

object named as

George Blumenschein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1

Tanguy Seiwert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

John Sarantopoulos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Howard Kallender

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Harold N Keer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

24 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

Investigational New Drugs

11 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

417-424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

11 February 2020

copyright license

start time

24 August 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s10637-012-9861-3

0 references

cites work

Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma

1 reference

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Advances in the management of recurrent or metastatic squamous cell carcinoma of the head and neck

30 September 2017

1 reference

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Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer.

30 September 2017

1 reference

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Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells

30 September 2017

1 reference

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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma

30 September 2017

1 reference

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Head and neck cancer: changing epidemiology and public health implications

30 September 2017

1 reference

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30 September 2017

Cancer statistics, 2010

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Epidermal growth factor receptor inhibitor gefitinib added to chemoradiotherapy in locally advanced head and neck cancer

30 September 2017

1 reference

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New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitors

30 September 2017

1 reference

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Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Platinum-based chemotherapy plus cetuximab in head and neck cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Head and neck cancer: changing epidemiology, diagnosis, and treatment

30 September 2017

1 reference

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Molecular metastases markers in head and neck squamous cell carcinoma: review of the literature.

30 September 2017

1 reference

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

VEGF is up-regulated by hypoxic stimulation and related to tumour angiogenesis and severity of disease in oral squamous cell carcinoma: in vitro and in vivo studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

30 September 2017

1 reference

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Toxicity and response criteria of the Eastern Cooperative Oncology Group

30 September 2017

1 reference

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Second malignant neoplasms in patients successfully treated with multimodality treatment for advanced head and neck cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Optimal two-stage designs for phase II clinical trials

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Phase II study of figitumumab in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: clinical activity and molecular response (GORTEC 2008-02).

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

A phase I study of foretinib, a multi-targeted inhibitor of c-Met and vascular endothelial growth factor receptor 2.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck [corrected].

20 September 2018

1 reference

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Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling.

20 September 2018

1 reference

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Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589657

Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Base

20 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10637-012-9861-3

A Phase II study of SU5416 in patients with advanced or recurrent head and neck cancers

21 January 2018

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Vascular endothelial growth factor in squamous cell head and neck carcinoma: expression and prognostic significance

1 reference

PubMed

12 December 2020

Evaluation of tissue and serum VEGF in patients with head and neck carcinoma

1 reference

PubMed

12 December 2020

10.1007/S10637-012-9861-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22918720%20AND%20SRC:MED&resulttype=core&format=json