(Q36663607)

English

Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization

scientific article published on 14 September 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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4

object named as

Bernard Moss

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

3

object named as

Gary J Nabel

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Jay A Berzofsky

5

object named as

Jay A Berzofsky

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Igor M Belyakov

1

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Europe PubMed Central

PMC publication ID

15 August 2017

Jeffrey D Ahlers

2

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Europe PubMed Central

PMC publication ID

15 August 2017

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publication date

14 September 2008

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Europe PubMed Central

PMC publication ID

15 August 2017

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Europe PubMed Central

PMC publication ID

15 August 2017

381

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Europe PubMed Central

PMC publication ID

15 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

106-115

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Enhanced cell surface expression, immunogenicity and genetic stability resulting from a spontaneous truncation of HIV Env expressed by a recombinant MVA.

1 reference

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Role of alpha3 domain of class I MHC molecules in the activation of high- and low-avidity CD8+ CTLs.

1 reference

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The impact of an AIDS vaccine in developing countries: a new model and initial results.

1 reference

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Multiple immunizations with adenovirus and MVA vectors improve CD8+ T cell functionality and mucosal homing

1 reference

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30 September 2017

A novel functional CTL avidity/activity compartmentalization to the site of mucosal immunization contributes to protection of macaques against simian/human immunodeficiency viral depletion of mucosal CD4+ T cells

1 reference

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Generation of gut-homing T cells and their localization to the small intestinal mucosa

1 reference

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1 reference

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Intramuscular rather than oral administration of replication-defective adenoviral vaccine vector induces specific CD8+ T cell responses in the gut.

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Prime-boost strategies in DNA vaccines.

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A DNA prime-oral Listeria boost vaccine in rhesus macaques induces a SIV-specific CD8 T cell mucosal response characterized by high levels of alpha4beta7 integrin and an effector memory phenotype.

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Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

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Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels

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Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa

1 reference

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

1 reference

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30 September 2017

Retinoic acid imprints gut-homing specificity on T cells

1 reference

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

1 reference

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30 September 2017

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

1 reference

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Progress on new vaccine strategies against chronic viral infections

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Mucosal AIDS vaccines: current status and future directions

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Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys

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Progress on new vaccine strategies for the immunotherapy and prevention of cancer

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30 September 2017

Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells

1 reference

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30 September 2017

Molecular mechanisms and biological significance of CTL avidity

1 reference

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30 September 2017

Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines

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Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

1 reference

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Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses

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30 September 2017

Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes

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Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

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Cytokine, Chemokine, and Costimulatory Molecule Modulation to Enhance Efficacy of HIV Vaccines

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Mucosal priming of simian immunodeficiency virus-specific cytotoxic T-lymphocyte responses in rhesus macaques by the Salmonella type III secretion antigen delivery system

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A review of vaccines for HIV prevention.

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High-affinity T helper epitope induces complementary helper and APC polarization, increased CTL, and protection against viral infection

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Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques

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Human immunodeficiency virus type 1-specific immunity after genetic immunization is enhanced by modification of Gag and Pol expression

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High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity

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Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.

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High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

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Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein.

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Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination

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HIV-1 diversity and vaccine development

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Protection by SIV VLP DNA prime/protein boost following mucosal SIV challenge is markedly enhanced by IL-12/GM-CSF co-administration

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Identifiers

10.1016/J.VIROL.2008.08.019

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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