(Q36665773)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Cooperative autoinhibition and multi-level activation mechanisms of calcineurin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

0 references

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0005955

Protein phosphatase 3 regulatory subunit B, alpha

1 reference

Protein phosphatase 3 catalytic subunit beta

1 reference

phosphatase binding

1 reference

Protein phosphatase 3, catalytic subunit, alpha isoform

1 reference

Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)

1 reference

author

Chang Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Sheng-Jie Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jue Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Lei Ma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jie Wang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jia-Wei Wu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Zhi-Xin Wang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

publication date

22 January 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

336-349

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cr.2016.14

5 March 2020

exact match

0 references

cites work

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1 reference

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The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

30 September 2017

1 reference

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Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Structural basis for activation of calcineurin by calmodulin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Interaction of calcineurin with substrates and targeting proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

NFAT proteins: emerging roles in cancer progression

30 September 2017

1 reference

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The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding

30 September 2017

1 reference

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Using fluorophore-labeled oligonucleotides to measure affinities of protein-DNA interactions

30 September 2017

1 reference

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Ca(2+)/calmodulin-dependent protein kinases

30 September 2017

1 reference

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Calpain-calcineurin signaling in the pathogenesis of calcium-dependent disorder

30 September 2017

1 reference

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Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

NFAT proteins: key regulators of T-cell development and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.

30 September 2017

1 reference

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Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

30 September 2017

1 reference

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NFAT signaling: choreographing the social lives of cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Calcineurin: form and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Calcineurin: from structure to function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Fluorescence anisotropy: rapid, quantitative assay for protein-DNA and protein-protein interaction.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

30 September 2017

1 reference

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Identification of an autoinhibitory domain in calcineurin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

30 September 2017

1 reference

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Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B

30 September 2017

1 reference

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A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants

30 September 2017

1 reference

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A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function

28 June 2018

1 reference

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The distal helix in the regulatory domain of calcineurin is important for domain stability and enzyme function.

28 June 2018

1 reference

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The secondary structure of calcineurin regulatory region and conformational change induced by calcium/calmodulin binding

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4783466

Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain

20 September 2018

1 reference

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Mechanism for the paradoxical inhibition and stimulation of calcineurin by the immunosuppresive drug tacrolimus (FK506)

20 September 2018

1 reference

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Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domain

20 September 2018

1 reference

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A renewed model of CNA regulation involving its C-terminal regulatory domain and CaM

20 September 2018

1 reference

12 December 2020

Probing the Ca2+/CaM-induced secondary structural and conformational changes in calcineurin

1 reference

12 December 2020

Regulation of calcineurin phosphatase activity by its autoinhibitory domain

1 reference

12 December 2020

Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A

1 reference

12 December 2020

Functional domain structure of calcineurin A: mapping by limited proteolysis

1 reference

12 December 2020

Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B

1 reference

12 December 2020

Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex

1 reference

12 December 2020

Targeted proteolysis sustains calcineurin activation

1 reference

12 December 2020

Kinetics of calmodulin binding to calcineurin

1 reference

12 December 2020

Calcineurin: From structure to function

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCR.2016.14

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/CR.2016.14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26794871%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference