(Q24535752)

peptidylprolyl isomerase A

1 reference

Protein phosphatase 3 catalytic subunit alpha

1 reference

cyclosporin A binding

1 reference

7

Hengming Ke

0 references

author name string

Qing Huai

1

0 references

Hwa-Young Kim

2

0 references

Yudong Liu

3

0 references

Yingdong Zhao

4

0 references

Angelo Mondragon

5

0 references

Jun O Liu

Proceedings of the National Academy of Sciences of the United States of America

6

0 references

language of work or name

English

0 references

publication date

17 September 2002

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published in

0 references

volume

99

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issue

19

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page(s)

12037-42

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cites work

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Convergent solutions to binding at a protein-protein interface

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

24 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

24 March 2017

https://api.crossref.org/works/10.1073/PNAS.192206699

Improved methods for building protein models in electron density maps and the location of errors in these models

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Calcineurin. Structure, function, and inhibition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Calcium control of adenylyl cyclase: the calcineurin connection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Calcineurin mutants render T lymphocytes resistant to cyclosporin A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Insights derived from the structures of the Ser/Thr phosphatases calcineurin and protein phosphatase 1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

The role of calcineurin in immune system responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Immunophilin-sensitive protein phosphatase action in cell signaling pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Role of Ca++/calmodulin binding proteins in Aspergillus nidulans cell cycle regulation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Expression and function of calcineurin in the mammalian nephron: physiological roles, receptor signaling, and ion transport

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129394

Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

Signal-transduction cascades as targets for therapeutic intervention by natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

The latch region of calcineurin B is involved in both immunosuppressant-immunophilin complex docking and phosphatase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.192206699

Cyclosporine and its analogue SDZ IMM 125 mediate very similar effects on T-cell activation--a comparative analysis in vitro

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12218175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12218175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.192206699

1 reference

ADS bibcode

2002PNAS...9912037H

0 references

1 reference

1 reference

PubMed publication ID

12218175

1 reference