(Q36670211)

15 August 2017

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title

Modelling the glucocorticoid receptor and producing therapeutic agents with anti-inflammatory effects but reduced side-effects (English)

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15 August 2017

David William Ray

2

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author name string

Andrew McMaster

series ordinal

1

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15 August 2017

publication date

30 November 2006

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15 August 2017

published in

Experimental Physiology

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15 August 2017

volume

92

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15 August 2017

issue

2

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15 August 2017

page(s)

299-309

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Ligand-dependent regulation of vascular endothelial growth factor and erythropoietin expression by a plasmid-based autoinducible GeneSwitch system

15 August 2017

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Beclomethasone dipropionate aerosol in treatment of perennial and seasonal rhinitis: a review of five years' experience

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Molecular mechanisms of glucocorticoid resistance/hypersensitivity. Potential clinical implications

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A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects

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Dexamethasone does not inhibit the release of mediators from human mast cells residing in airway, intestine, or skin

21 January 2018

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A role for brain glucocorticoid receptors in contextual fear conditioning: dependence upon training intensity.

21 January 2018

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A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate

21 January 2018

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Effects of in vitro corticosteroids on B cell activation, proliferation, and differentiation

21 January 2018

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A fully dissociated compound of plant origin for inflammatory gene repression

21 January 2018

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Molecular chaperones function as steroid receptor nuclear mobility factors

21 January 2018

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A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats

21 January 2018

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Inhibition of glucocorticoid receptor nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton

21 January 2018

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Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus

21 January 2018

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Glucocorticoid Ligands Specify Different Interactions with NF-κB by Allosteric Effects on the Glucocorticoid Receptor DNA Binding Domain

21 January 2018

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A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance

21 January 2018

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Transcription factor regulation in mammary epithelial cells

21 January 2018

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Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

21 January 2018

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Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma.

21 January 2018

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Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor

21 January 2018

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11beta-Hydroxysteroid dehydrogenase type 2 protects the neonatal cerebellum from deleterious effects of glucocorticoids

21 January 2018

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Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells

21 January 2018

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Modulation of glucocorticoid receptor function via phosphorylation.

21 January 2018

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Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

21 January 2018

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The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism

21 January 2018

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Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesity

21 January 2018

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Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor

21 January 2018

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Receptor-mediated effects of glucocorticoids on inflammation: enhancement of the inflammatory response with a glucocorticoid antagonist

21 January 2018

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Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta

21 January 2018

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Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins

21 January 2018

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The origin and functions of multiple human glucocorticoid receptor isoforms

21 January 2018

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Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes.

21 January 2018

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Deflazacort. A review of its pharmacological properties and therapeutic efficacy

21 January 2018

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Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box.

21 January 2018

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Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling

21 January 2018

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Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription?

21 January 2018

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NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms

21 January 2018

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

21 January 2018

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Results of a search for the mechanisms of steroid receptor regulation of gene expression

21 January 2018

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A life-long search for the molecular pathways of steroid hormone action

21 January 2018

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Genetic manipulation of 11beta-hydroxysteroid dehydrogenases in mice

21 January 2018

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Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis

21 January 2018

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Perinatal corticosteroids: A review of research. Part I: Antenatal administration

21 January 2018

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DNA binding of the glucocorticoid receptor is not essential for survival

21 January 2018

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Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor

21 January 2018

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Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth

21 January 2018

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Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

21 January 2018

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https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

The search for safer glucocorticoid receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Review article: medical treatment of moderate to severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

11beta-hydroxysteroid dehydrogenases: changing glucocorticoid action

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

11Beta-hydroxysteroid dehydrogenases: a novel control of glucocorticoid action in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Imbalanced expression of the glucocorticoid receptor isoforms in cultured lymphocytes from a patient with systemic glucocorticoid resistance and chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Tissue-specific Cushing's syndrome, 11beta-hydroxysteroid dehydrogenases and the redefinition of corticosteroid hormone action

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Evolution of glucocorticoid receptors with different glucocorticoid sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

High constitutive glucocorticoid receptor beta in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Cell type-dependent divergence of transactivation by glucocorticoid receptor ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Modulation of Glucocorticoid Receptor Transcriptional Activation, Phosphorylation, and Growth Inhibition by p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Transcriptional regulation by steroid receptor coactivator phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Molecular origins for the dominant negative function of human glucocorticoid receptor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

Correlational relationship between shock intensity and corticosterone secretion on the establishment and subsequent expression of contextual fear conditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.036194

10.1113/EXPPHYSIOL.2006.036194

21 January 2018

Identifiers

DOI

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15 August 2017

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