(Q36672152)

15 August 2017

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title

The contribution of epidermal stem cells to skin cancer (English)

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15 August 2017

2

Stuart H Yuspa

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15 August 2017

Michael J Gerdes

1

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15 August 2017

publication date

1 January 2005

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Stem Cell Reviews and Reports

15 August 2017

published in

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15 August 2017

volume

1

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15 August 2017

issue

3

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15 August 2017

page(s)

225-231

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Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis

15 August 2017

cites work

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12 December 2020

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

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12 December 2020

Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

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12 December 2020

Essential role for Sonic hedgehog during hair follicle morphogenesis

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12 December 2020

Quantitation of primary in vitro clonogenic keratinocytes from normal adult murine epidermis, following initiation, and during promotion of epidermal tumors

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12 December 2020

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

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12 December 2020

Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma.

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12 December 2020

c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny

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12 December 2020

Association of p63 with proliferative potential in normal and neoplastic human keratinocytes

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12 December 2020

Side population cells in human and mouse epidermis lack stem cell characteristics

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12 December 2020

Highly persistent label-retaining cells in the hair follicles of mice and their fate following induction of anagen

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12 December 2020

A common human skin tumour is caused by activating mutations in beta-catenin

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12 December 2020

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

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12 December 2020

p63 is a p53 homologue required for limb and epidermal morphogenesis

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12 December 2020

Morphogenesis and renewal of hair follicles from adult multipotent stem cells

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12 December 2020

Follicular origin of epidermal papillomas in v-Ha-ras transgenic TG.AC mouse skin

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12 December 2020

Somatic epidermal stem cells can produce multiple cell lineages during development

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12 December 2020

Role of oncogenes and tumor suppressor genes in multistage carcinogenesis.

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12 December 2020

Myc lacks E2F1's ability to suppress skin carcinogenesis

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12 December 2020

High frequency of p53 mutations in ultraviolet radiation-induced murine skin tumors: evidence for strand bias and tumor heterogeneity

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12 December 2020

The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.

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12 December 2020

c-Myc and epidermal stem cell fate determination

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12 December 2020

Capturing and profiling adult hair follicle stem cells.

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12 December 2020

Muir-Torre-like syndrome in Fhit-deficient mice

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12 December 2020

Mouse skin is particularly susceptible to tumor initiation during early anagen of the hair cycle: possible involvement of hair follicle stem cells.

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12 December 2020

Defining the epithelial stem cell niche in skin

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12 December 2020

Enrichment for murine keratinocyte stem cells based on cell surface phenotype

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12 December 2020

Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis

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12 December 2020

Label-retaining keratinocytes and Langerhans cells in mouse epithelia

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12 December 2020

Evidence that initiated keratinocytes clonally expand into multiple existing hair follicles during papilloma histogenesis in SENCAR mouse skin

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12 December 2020

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

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12 December 2020

Detection of telomerase activity in malignant and nonmalignant skin conditions

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12 December 2020

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

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12 December 2020

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

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12 December 2020

Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential formation of two types of mouse hair follicles

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12 December 2020

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

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12 December 2020

An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

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12 December 2020

Phospholipase Cdelta1 is required for skin stem cell lineage commitment

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12 December 2020

Evidence that a slowly cycling subpopulation of adult murine epidermal cells retains carcinogen

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12 December 2020

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

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12 December 2020

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

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12 December 2020

Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination

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12 December 2020

Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development

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12 December 2020

Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors

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12 December 2020

Activation of expression of hedgehog target genes in basal cell carcinomas

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12 December 2020

Conditional gene expression in the epidermis of transgenic mice using the tetracycline-regulated transactivators tTA and rTA linked to the keratin 5 promoter

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12 December 2020

Clonal origin of chemically induced papillomas: separate analysis of epidermal and dermal components.

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12 December 2020

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

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12 December 2020

The cellular origin of chemically induced tumours

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12 December 2020

Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency

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12 December 2020

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

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12 December 2020

A comparison of interfollicular and hair follicle derived cells as targets for the v-rasHa oncogene in mouse skin carcinogenesis

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12 December 2020

Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin

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12 December 2020

Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogene

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12 December 2020

Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling

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12 December 2020

Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin

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12 December 2020

Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes

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12 December 2020

Epidermal stem cells: interactions in developmental environments

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12 December 2020

Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles

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12 December 2020

Telomerase is not an epidermal stem cell marker and is downregulated by calcium

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12 December 2020

Papillomas induced by initiation-promotion differ from those induced by carcinogen alone.

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12 December 2020

On the clonal origin of tumors: a review of experimental models

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12 December 2020

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle

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12 December 2020

Involvement of follicular stem cells in forming not only the follicle but also the epidermis

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12 December 2020

Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis

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12 December 2020

Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge.

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12 December 2020

Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage.

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12 December 2020

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

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12 December 2020

Enrichment and characterization of mouse putative epidermal stem cells

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12 December 2020

The hedgehog pathway and basal cell carcinomas

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12 December 2020

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

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12 December 2020

A possible role for human papillomaviruses and c-myc, c-Ha-ras, and p53 gene alterations in malignant cutaneous lesions from renal transplant recipients

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12 December 2020

Deregulated expression of c-Myc depletes epidermal stem cells

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12 December 2020

Wnt signalling in stem cells and cancer

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12 December 2020

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

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12 December 2020

Integrins and basement membrane proteins in skin carcinomas.

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12 December 2020

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

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12 December 2020

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12 December 2020

Side population keratinocytes resembling bone marrow side population stem cells are distinct from label-retaining keratinocyte stem cells

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12 December 2020

p63 identifies keratinocyte stem cells

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12 December 2020

Hedgehog signaling regulates sebaceous gland development

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12 December 2020

The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells.

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12 December 2020

Human epidermal cancer and accompanying precursors have identical p53 mutations different from p53 mutations in adjacent areas of clonally expanded non-neoplastic keratinocytes

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12 December 2020

Telomerase activity concentrates in the mitotically active segments of human hair follicles

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12 December 2020

Intraclonal conversion from papilloma to carcinoma in the skin of Pgk-1a/Pgk-1b mice treated by a complete carcinogenesis process or by an initiation-promotion regimen.

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12 December 2020

Clonal origin of tumors induced by ultraviolet radiation.

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12 December 2020

Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin

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12 December 2020

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

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12 December 2020

Target genes and target cells in carcinogenesis.

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12 December 2020

Unexpected Hedgehog-Wnt interactions in epithelial differentiation

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12 December 2020

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

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12 December 2020

Expression of the alpha 6 beta 4 integrin by squamous cell carcinomas and basal cell carcinomas: possible relation to invasive potential?

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12 December 2020

Identifiers

DOI

10.1385/SCR:1:3:225

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Dimensions Publication ID

15 August 2017

1009716804

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