(Q36674306)

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A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies.

scientific article published on 20 January 2016

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26792581%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26792581%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

10

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5 March 2020

Jan H M Schellens

12

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Jan H M Schellens

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5 March 2020

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Geert A Cirkel

1

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5 March 2020

Bojana Milojkovic Kerklaan

2

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5 March 2020

Frédéric Vanhoutte

3

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5 March 2020

Annegret Van der Aa

4

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5 March 2020

Giocondo Lorenzon

5

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5 March 2020

Florence Namour

6

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5 March 2020

Philippe Pujuguet

7

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5 March 2020

Sophie Darquenne

8

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5 March 2020

Filip Y F de Vos

9

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5 March 2020

Emile E Voest

11

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5 March 2020

Martijn P Lolkema

13

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5 March 2020

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20 January 2016

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5 March 2020

Investigational New Drugs

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5 March 2020

34

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5 March 2020

2

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5 March 2020

184-192

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5 March 2020

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Creative Commons Attribution 4.0 International

20 January 2016

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April 2022 Public Data File from Crossref

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0 references

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1 reference

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Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study

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Integrin inhibition promotes atypical anoikis in glioma cells

1 reference

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30 September 2017

Integrin control of the transforming growth factor-β pathway in glioblastoma.

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A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306)

1 reference

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30 September 2017

Integrins in cell migration

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30 September 2017

Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma

1 reference

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30 September 2017

Integrins in cancer: biological implications and therapeutic opportunities

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New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

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30 September 2017

Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme

1 reference

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30 September 2017

Integrins in angiogenesis and lymphangiogenesis

1 reference

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30 September 2017

Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.

1 reference

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30 September 2017

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

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30 September 2017

Serum CTX: a new marker of bone resorption that shows treatment effect more often than other markers because of low coefficient of variability and large changes with bisphosphonate therapy

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A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo

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30 September 2017

End of the road: confounding results of the CORE trial terminate the arduous journey of cilengitide for glioblastoma

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28 June 2018

The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor

1 reference

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28 June 2018

Does cilengitide deserve another chance?

1 reference

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Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group

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20 September 2018

Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery.

1 reference

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20 September 2018

Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death.

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Catheter-related infections: diagnosis and intravascular treatment

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Circadian variation of urinary type I collagen crosslinked C-telopeptide and free and peptide-bound forms of pyridinium crosslinks

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Diurnal rhythm of CrossLaps in human serum

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12 December 2020

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10.1007/S10637-015-0320-9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26792581%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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Europe PubMed Central

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5 March 2020

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5 March 2020

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