(Q36674761)

English

Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts

scientific article published on 11 January 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

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author name string

James H Doroshow

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Shikha Gaur

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Susan Markel

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Jiamo Lu

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Josephus van Balgooy

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Timothy W Synold

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Bixin Xi

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Xiwei Wu

8

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Europe PubMed Central

PMC publication ID

15 August 2017

Agnes Juhasz

9

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Europe PubMed Central

PMC publication ID

15 August 2017

publication date

11 January 2013

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Europe PubMed Central

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15 August 2017

Free Radical Biology and Medicine

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Europe PubMed Central

PMC publication ID

15 August 2017

57

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Europe PubMed Central

PMC publication ID

15 August 2017

162-175

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3594408/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3594408

based on heuristic

inferred from PubMed Central ID database lookup

Targeting NADPH oxidases for the treatment of cancer and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma

1 reference

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30 September 2017

Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel

1 reference

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30 September 2017

NADPH oxidase inhibitors: a patent review

1 reference

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30 September 2017

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

1 reference

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30 September 2017

NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability

1 reference

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Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines

1 reference

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30 September 2017

Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

1 reference

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30 September 2017

Nox proteins in signal transduction

1 reference

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30 September 2017

Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases

1 reference

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30 September 2017

Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Emerging evidence for the importance of phosphorylation in the regulation of NADPH oxidases

1 reference

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30 September 2017

Overexpression of catalase delays G0/G1- to S-phase transition during cell cycle progression in mouse aortic endothelial cells

1 reference

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30 September 2017

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets

1 reference

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30 September 2017

Redox regulation of nuclear post-translational modifications during NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Classical inhibitors of NOX NAD(P)H oxidases are not specific.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype

1 reference

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30 September 2017

Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Regulation of normal cell cycle progression by flavin-containing oxidases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

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30 September 2017

A redox cycle within the cell cycle: ring in the old with the new.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Tissue distribution and putative physiological function of NOX family NADPH oxidases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Diphenyleneiodonium inhibits the cell redox metabolism and induces oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

ROS stress in cancer cells and therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Alpha2beta1-integrin signaling by itself controls G1/S transition in a human adenocarcinoma cell line (Caco-2): implication of NADPH oxidase-dependent production of ROS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Reactive oxygen generated by Nox1 triggers the angiogenic switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

The Pezcoller lecture: cancer cell cycles revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

30 September 2017

Phosphorylation of NADPH oxidase activator 1 (NOXA1) on serine 282 by MAP kinases and on serine 172 by protein kinase C and protein kinase A prevents NOX1 hyperactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

The inhibition by diphenyleneiodonium and its analogues of superoxide generation by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

28 June 2018

Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

20 September 2018

Dual oxidases and hydrogen peroxide in a complex dialogue between host mucosae and bacteria

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

20 September 2018

Differential role of diphenyleneiodonium, a flavoenzyme inhibitor, on p53-dependent and -independent cell cycle progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

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20 September 2018

NAD(P)H oxidases regulate HIF-2alpha protein expression.

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20 September 2018

Redox regulation of the G1 to S phase transition in the mouse embryo fibroblast cell cycle.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594408

20 September 2018

Diphenylene iodonium as an inhibitor of the NADPH oxidase complex of bovine neutrophils. Factors controlling the inhibitory potency of diphenylene iodonium in a cell-free system of oxidase activation

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells

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https://pubmed.ncbi.nlm.nih.gov/23314043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.FREERADBIOMED.2013.01.002

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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