(Q36678037)

15 August 2017

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title

New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors (English)

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15 August 2017

main subject

transmembrane protein

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1

Robert J Lefkowitz

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15 August 2017

Keshava Rajagopal

2

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15 August 2017

Erin J Whalen

series ordinal

3

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15 August 2017

publication date

1 December 2006

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15 August 2017

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15 August 2017

volume

24

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15 August 2017

issue

5

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15 August 2017

page(s)

643-652

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beta-Arrestin: a protein that regulates beta-adrenergic receptor function

15 August 2017

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.2163110

Activation-dependent conformational changes in {beta}-arrestin 2.

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11 October 2022

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Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors

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11 October 2022

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Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

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11 October 2022

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A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila.

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11 October 2022

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Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Transduction of receptor signals by beta-arrestins

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

G protein-coupled receptor kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The new face of active receptor bound arrestin attracts new partners

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Regulation of Notch signalling by non-visual beta-arrestin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Regulation of arrestin-3 phosphorylation by casein kinase II

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The ins and outs of G protein-coupled receptor trafficking

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

G proteins: transducers of receptor-generated signals

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-arrestins regulate interleukin-8-induced CXCR1 internalization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Seven-transmembrane receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The neurobiology of slow synaptic transmission

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Phosphoserine/threonine-binding domains

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Role of beta-arrestin 1 in the metastatic progression of colorectal cancer

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Arrestins block G protein-coupled receptor-mediated apoptosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

X-ray crystal structure of arrestin from bovine rod outer segments

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Arrestin serves as a molecular switch, linking endogenous alpha2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Membrane trafficking of G protein-coupled receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Beta-arrestin-2 regulates the development of allergic asthma

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Visual and both non-visual arrestins in their "inactive" conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasm

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

The Hedgehog response network: sensors, switches, and routers

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein)

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2006.11.007

Identifiers

DOI

10.1016/J.MOLCEL.2006.11.007

1 reference

15 August 2017

1 reference