(Q36686904)

15 August 2017

1 reference

title

The role of GABA in the mediation and perception of pain (English)

1 reference

15 August 2017

S J Enna

1

1 reference

15 August 2017

Kenneth E McCarson

series ordinal

2

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15 August 2017

publication date

1 January 2006

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15 August 2017

published in

Advances in Pharmacology

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15 August 2017

volume

54

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15 August 2017

page(s)

1-27

1 reference

Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain

15 August 2017

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Spinal GABAB receptors mediate antinociceptive actions of cholinergic agents in normal and diabetic rats

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Constitutive expression of functional GABA(B) receptors in mIL-tsA58 cells requires both GABA(B(1)) and GABA(B(2)) genes

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Evidence for pharmacologically distinct GABAB receptors associated with cAMP production in rat brain

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GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat.

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Coexistence of GABAA and GABAB receptors on A delta and C primary afferents

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Continuous administration of the 5-hydroxytryptamine1A agonist (3-Chloro-4-fluoro-phenyl)-[4-fluoro-4-[[(5-methyl-pyridin-2-ylmethyl) -amino]-methyl]piperidin-1-yl]-methadone (F 13640) attenuates allodynia-like behavior in a rat model of trigeminal

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7 January 2021

Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn

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7 January 2021

GABAergic modulation of nociceptive threshold: effects of THIP and bicuculline microinjected in the ventral medulla of the rat

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7 January 2021

Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial

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7 January 2021

A single intrathecal injection of GABA permanently reverses neuropathic pain after nerve injury

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7 January 2021

GABAB receptor agonists and antagonists: pharmacological properties and therapeutic possibilities

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7 January 2021

Regulation of neurokinin-1 receptor expression by GABA(B) receptor agonists

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7 January 2021

Baclofen as an adjuvant analgesic

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7 January 2021

Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.

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7 January 2021

The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

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7 January 2021

GABAergic modulation of descending inhibitory systems from the rostral ventromedial medulla (RVM). Dose-response analysis of nociception and neurological deficits

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7 January 2021

GABA-receptor control of the amplitude and duration of the neuronal responses to formalin in the rat spinal cord

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7 January 2021

Comparison of the analgesic actions of THIP and morphine

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7 January 2021

The effect of antinociceptive drugs tested at different times after nerve injury in rats

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7 January 2021

Differential distribution of (GABA)A receptor subunits on bulbospinal serotonergic and nonserotonergic neurons of the ventromedial medulla of the rat.

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7 January 2021

Effects of intrathecally administered THIP, baclofen and muscimol on nociceptive threshold

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7 January 2021

Analgesic properties of the GABA-mimetic THIP

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7 January 2021

Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons

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Significance of GABAergic systems in the action of improgan, a non-opioid analgesic

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7 January 2021

The effect of spinal GABA receptor agonists on tactile allodynia in a surgically-induced neuropathic pain model in the rat.

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7 January 2021

The interaction between intrathecal neostigmine and GABA receptor agonists in rats with nerve ligation Injury

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7 January 2021

Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts

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7 January 2021

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7 January 2021

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7 January 2021

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

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7 January 2021

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7 January 2021

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7 January 2021

New targets for neuropathic pain therapeutics

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7 January 2021

GABAergic projection from the ventral tegmental area and substantia nigra to the periaqueductal gray region and the dorsal raphe nucleus

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7 January 2021

The analgesic effect of the GABA-agonist THIP in patients with chronic pain of malignant origin. A phase-1-2 study

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7 January 2021

A deficit of functional GABA(A) receptors in neurons of beta 3 subunit knockout mice

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7 January 2021

GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects

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7 January 2021

GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic

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7 January 2021

Towards a view of functioning dimeric metabotropic receptors

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7 January 2021

Gabapentin is not a GABAB receptor agonist

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7 January 2021

Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception

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7 January 2021

Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats

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7 January 2021

Intrathecal baclofen as adjuvant therapy to enhance the effect of spinal cord stimulation in neuropathic pain: a pilot study

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7 January 2021

Effects of intrathecal baclofen on chronic spinal cord injury pain

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7 January 2021

Effect of intracerebroventricular injection of GABA receptor agents on morphine-induced antinociception in the formalin test

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7 January 2021

Spinal GABA(A) and GABA(B) receptor pharmacology in a rat model of neuropathic pain

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7 January 2021

Spinal cord SP release and hyperalgesia in monoarthritic rats: involvement of the GABAB receptor system

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7 January 2021

Chronic (-)baclofen or CGP 36742 alters GABAB receptor sensitivity in rat brain and spinal cord

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7 January 2021

Antagonism of the antinocifensive action of halothane by intrathecal administration of GABAA receptor antagonists.

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7 January 2021

Nociceptive regulation of GABA(B) receptor gene expression in rat spinal cord

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7 January 2021

Amitriptyline prevents thermal hyperalgesia and modifications in rat spinal cord GABA(B) receptor expression and function in an animal model of neuropathic pain

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7 January 2021

GABA(B) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants.

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7 January 2021

Muscimol prevents long-lasting potentiation of dorsal horn field potentials in rats with chronic constriction injury exhibiting decreased levels of the GABA transporter GAT-1.

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7 January 2021

Specific GABA(A) circuits in brain development and therapy.

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7 January 2021

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

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7 January 2021

A comparison of the analgesic activities of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) and 6-chloro-2[1-piperazinyl]pyrazine (MK 212)

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7 January 2021

Interaction between gamma-aminobutyric acid GABAB and cannabinoid CB1 receptors in spinal pain pathways in rat.

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7 January 2021

Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.

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7 January 2021

Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice

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7 January 2021

Treatment of painful sensory neuropathy with tiagabine: a pilot study

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7 January 2021

Brain Stem Opioidergic and GABAergic Neurons Mediate the Antinociceptive Effect of Nitrous Oxide in Fischer Rats

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7 January 2021

GABAergic interneurons at supraspinal and spinal levels differentially modulate the antinociceptive effect of nitrous oxide in Fischer rats

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7 January 2021

The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat.

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7 January 2021

An antinociceptive profile of kojic amine: an analogue of gamma-aminobutyric acid (GABA)

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7 January 2021

Noxious‐evoked c‐fos expression in brainstem neurons immunoreactive for GABAB, µ‐opioid and NK‐1 receptors

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7 January 2021

Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain.

1 reference

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7 January 2021

Are baclofen-sensitive GABAB receptors present on primary afferent terminals of the spinal cord?

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7 January 2021

The parafasciculus thalami as a site for mediating the antinociceptive response to GABAergic drugs

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7 January 2021

Presynaptic regulation of spinal cord tachykinin signaling via GABA(B) but not GABA(A) receptor activation

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7 January 2021

Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain

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7 January 2021

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

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7 January 2021

Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial.

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7 January 2021

Differential regulation of GABA B receptor subunit expression and function.

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7 January 2021

Relationship between the antinociceptive response to desipramine and changes in GABAB receptor function and subunit expression in the dorsal horn of the rat spinal cord.

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7 January 2021

Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).

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7 January 2021

Involvement of GABAB receptors in the antinociception induced by baclofen in the formalin test

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7 January 2021

Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects

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7 January 2021

Pharmacotherapy of trigeminal neuralgia

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7 January 2021

Increased sensitivity to the antinociceptive activity of (+/-)-baclofen in an animal model of chronic neuropathic, but not chronic inflammatory hyperalgesia

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7 January 2021

Dorsal horn synaptosomal content of aspartate, glutamate, glycine and GABA are differentially altered following chronic constriction injury to the rat sciatic nerve

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7 January 2021

The GABA transporter and its inhibitors

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7 January 2021

Tolerance pattern to GABAmimetic analgesics and their influence on morphine tolerance and dependence

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7 January 2021

Antinociception produced by systemic R(+)-baclofen hydrochloride is attenuated by CGP 35348 administered to the spinal cord or ventromedial medulla of rats.

1 reference

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7 January 2021

Tiagabine and gabapentin for the management of chronic pain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2806%2954001-3

7 January 2021

Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor.

1 reference

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7 January 2021

N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

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7 January 2021

GABA(B) receptors as potential therapeutic targets

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7 January 2021

A comparison of the antinociceptive responses to the GABA-receptor agonists THIP and baclofen

1 reference

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7 January 2021

Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats

1 reference

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7 January 2021

Involvement of GABA and opioid peptide receptors in sevoflurane-induced antinociception in rat spinal cord

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7 January 2021

Origins of GABA(B) receptor-like immunoreactive terminals in the rat spinal dorsal horn

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7 January 2021

Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors

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7 January 2021

Effects of diazepam on nociception in rats

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7 January 2021

GABA mechanisms and antinociception in mice with ligated sciatic nerve

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7 January 2021

GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice

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7 January 2021

Function of gamma-aminobutyric acid receptor/channel rho 1 subunits in spinal cord

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7 January 2021

GABA uptake inhibitors produce a greater antinociceptive response in the mouse tail-immersion assay than other types of GABAergic drugs

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7 January 2021

The effect of mouse spinal cord transection on the antinociceptive response to the gamma-aminobutyric acid agonists THIP (4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridine-3-ol) and baclofen

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7 January 2021

The GABA agonist THIP, attenuates antinociception in the mouse by modifying central cholinergic transmission

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7 January 2021

10.1016/S1054-3589(06)54001-3

Identifiers

DOI

1 reference

15 August 2017

1 reference