(Q36688667)

15 August 2017

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title

Gene therapy of the other genome: the challenges of treating mitochondrial DNA defects (English)

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15 August 2017

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Gerard G M D'Souza

1

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15 August 2017

Sarathi V Boddapati

series ordinal

2

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15 August 2017

Volkmar Weissig

series ordinal

3

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15 August 2017

publication date

19 December 2006

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15 August 2017

published in

Pharmaceutical Research

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15 August 2017

volume

24

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15 August 2017

issue

2

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15 August 2017

page(s)

228-238

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Import and assembly of proteins into mitochondria of mammalian cells

15 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells

21 January 2018

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Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration

21 January 2018

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Structural requirements of tRNALys for its import into yeast mitochondria

21 January 2018

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Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells.

21 January 2018

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Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage

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Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria

21 January 2018

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Targeting of O6-MeG DNA methyltransferase (MGMT) to mitochondria protects against alkylation induced cell death

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Gene therapy by mitochondrial transfer

21 January 2018

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Transformation of isolated mammalian mitochondria by bacterial conjugation

21 January 2018

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Efficient cloning and engineering of entire mitochondrial genomes in Escherichia coli and transfer into transcriptionally active mitochondria

21 January 2018

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Virus factories: associations of cell organelles for viral replication and morphogenesis

21 January 2018

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Molecular basis for mitochondrial localization of viral particles during beet necrotic yellow vein virus infection

21 January 2018

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Rubella virus capsid associates with host cell protein p32 and localizes to mitochondria

21 January 2018

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Development of Mitochondrial Gene Replacement Therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

Approaches to mitochondrial gene therapy

21 January 2018

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Mitochondrial-targeted drug and DNA delivery

21 January 2018

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Mitochondriotropic liposomes

21 January 2018

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Mitochondriotropic cationic vesicles: a strategy towards mitochondrial gene therapy

21 January 2018

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Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems

21 January 2018

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DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria

21 January 2018

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DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells

21 January 2018

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Expression of green fluorescent protein from a recoded gene inserted into Saccharomyces cerevisiae mitochondrial DNA.

21 January 2018

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Synthesis of a modified gene encoding human ornithine transcarbamylase for expression in mammalian mitochondrial and universal translation systems: a novel approach towards correction of a genetic defect

21 January 2018

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An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

21 January 2018

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Modification of the mouse mitochondrial genome by insertion of an exogenous gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

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Production of mitochondrial DNA transgenic mice using zygotes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

5 S rRNA and tRNA import into human mitochondria. Comparison of in vitro requirements

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

DNA-protein conjugates can enter mitochondria via the protein import pathway.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-006-9150-Y

Transformation of Saccharomyces cerevisiae mitochondria using the biolistic gun

21 January 2018

1 reference

12 December 2020

Nucleotide exchange in genomic DNA of rat hepatocytes using RNA/DNA oligonucleotides. Targeted delivery of liposomes and polyethyleneimine to the asialoglycoprotein receptor

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12 December 2020

Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress

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12 December 2020

Heterologous mitochondrial DNA recombination in human cells

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12 December 2020

Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents

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12 December 2020

Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide

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12 December 2020

Conversion of a reporter gene for mitochondrial gene expression using iterative mega-prime PCR

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12 December 2020

Mitochondria transfer into mouse ova by microinjection

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12 December 2020

Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes

1 reference

12 December 2020

Impaired mitochondrial translation in human myoblasts harbouring the mitochondrial DNA tRNA lysine 8344 A → G (MERRF) mutation: relationship to proportion of mutant mitochondrial DNA

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12 December 2020

Dequalinium vesicles form stable complexes with plasmid DNA which are protected from DNase attack

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12 December 2020

Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria

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12 December 2020

Suppression of mutations in mitochondrial DNA by tRNAs imported from the cytoplasm

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12 December 2020

The aminoacceptor stem of the yeast tRNA(Lys) contains determinants of mitochondrial import selectivity

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12 December 2020

Introduction of plasmid DNA into isolated mitochondria by electroporation. A novel approach toward gene correction for mitochondrial disorders

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12 December 2020

Functional expression of the single subunit NADH dehydrogenase in mitochondria in vivo: a potential therapy for complex I deficiencies

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12 December 2020

Oligonucleotide-mediated site-directed gene repair

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12 December 2020

Preference of human mitochondrial RNA polymerase for superhelical templates with mitochondrial promoters

1 reference

12 December 2020

10.1007/S11095-006-9150-Y

Identifiers

DOI

1 reference

release_cpprw6wwkfdzpeagjtgdnvlfwy

15 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/cpprw6wwkfdzpeagjtgdnvlfwy

24 November 2022

mapped directly with Wikidata item

1 reference