(Q36688699)

15 August 2017

Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice (English)

1 reference

15 August 2017

hepatocellular carcinoma

1 reference

1 reference

13

1 reference

15 August 2017

Rune Matthiesen

10

0 references

author name string

M Luz Martínez-Chantar

1

1 reference

15 August 2017

Mercedes Vázquez-Chantada

2

1 reference

15 August 2017

Usue Ariz

3

1 reference

15 August 2017

Nuria Martínez

4

1 reference

15 August 2017

Marta Varela

5

1 reference

15 August 2017

Zigmund Luka

6

1 reference

15 August 2017

Antonieta Capdevila

7

1 reference

15 August 2017

Juan Rodríguez

8

1 reference

15 August 2017

Ana M Aransay

9

1 reference

15 August 2017

Heping Yang

11

1 reference

15 August 2017

Diego F Calvisi

12

1 reference

15 August 2017

Mario Fraga

14

1 reference

15 August 2017

Shelly C Lu

15

1 reference

15 August 2017

Conrad Wagner

16

1 reference

15 August 2017

José M Mato

17

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 April 2008

1 reference

15 August 2017

1 reference

15 August 2017

47

1 reference

15 August 2017

1191-1199

1 reference

15 August 2017

4

1 reference

Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

High-resolution profiling of histone methylations in the human genome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Role of S-adenosyl-L-methionine in liver health and injury

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Cancer epigenomics: DNA methylomes and histone-modification maps

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Role of the Ras-association domain family 1 tumor suppressor gene in human cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Glycine N -methyltransferase deficiency: a new patient with a novel mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Characterization of glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Purification and properties of glycine N-methyltransferase from rat liver

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Methyl balance and transmethylation fluxes in humans.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Tumor susceptibility of Rassf1a knockout mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2405897

All-trans-retinoic acid rapidly induces glycine N-methyltransferase in a dose-dependent manner and reduces circulating methionine and homocysteine levels in rats

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18318442

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18318442

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18318442

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/HEP.22159

1 reference

15 August 2017

1 reference

15 August 2017

1 reference