(Q36689662)

15 August 2017

Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery (English)

1 reference

15 August 2017

Eradication of pathogenic β-catenin by Skp1/Cullin/F box ubiquitination machinery (English)

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

eradication of infectious diseases

22 March 2024

main subject

1 reference

inferred from title

protein ubiquitination

1 reference

Yunyun Su

1

1 reference

15 August 2017

Shinji Ishikawa

series ordinal

2

1 reference

15 August 2017

Masayuki Kojima

series ordinal

3

1 reference

15 August 2017

Bo Liu

series ordinal

4

1 reference

15 August 2017

language of work or name

English

0 references

publication date

16 October 2003

1 reference

full work available at URL

15 August 2017

https://europepmc.org/articles/pmc240686?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14563921

https://europepmc.org/articles/PMC240686

22 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14563921

https://europepmc.org/articles/PMC240686?pdf=render

22 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14563921

https://doi.org/10.1073/pnas.2133261100

22 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14563921

https://pnas.org/doi/pdf/10.1073/pnas.2133261100

22 March 2024

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

Proceedings of the National Academy of Sciences of the United States of America

22 March 2024

published in

1 reference

15 August 2017

100

1 reference

15 August 2017

22

1 reference

15 August 2017

12729-12734

1 reference

describes a project that uses

15 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC240686/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Linking colorectal cancer to Wnt signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Essential role for oncogenic Ras in tumour maintenance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Identification of c-MYC as a target of the APC pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

beta-catenin is a target for the ubiquitin-proteasome pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

The adenomatous polyposis coli (APC) tumor suppressor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Yeast surface display for screening combinatorial polypeptide libraries

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Cadherin-catenin complex: protein interactions and their implications for cadherin function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Functional interaction of beta-catenin with the transcription factor LEF-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Amyloid beta-protein and the genetics of Alzheimer's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Apoptosis and APC in colorectal tumorigenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Defective protein folding as a basis of human disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Association of the APC tumor suppressor protein with catenins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Association of the APC gene product with beta-catenin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Redirecting the specificity of ubiquitination by modifying ubiquitin-conjugating enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

A novel genetic system to detect protein-protein interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

The ubiquitin system for protein degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Hypermutability and mismatch repair deficiency in RER+ tumor cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

beta-TrCP is a negative regulator of Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2133261100

The role of protein stability in the cell cycle and cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240686

Cadherin-catenin complex: Protein interactions and their implications for cadherin function

5 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2133261100

Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2133261100

Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14563921

12 December 2020

inferred from PubMed ID database lookup

Proof-of-principle: oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14563921

12 December 2020

inferred from PubMed ID database lookup

Biochimica et Biophysica Acta

8

1332

F127

1997

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

22 March 2024

16

62

2744

2002

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

22 March 2024

22

55

5187

1995

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

22 March 2024

24

60

1671

2000

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

Biochimica et Biophysica Acta

22 March 2024

33

1377

M61

1998

1 reference

https://api.crossref.org/works/10.1073/PNAS.2133261100

22 March 2024

Identifiers

1 reference

15 August 2017

0 references

1 reference

15 August 2017

1 reference