(Q36695591)

15 August 2017

An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis (English)

1 reference

15 August 2017

1

Xiumei Huang

1 reference

15 August 2017

Ying Dong

2

1 reference

15 August 2017

Erik A Bey

3

1 reference

15 August 2017

Jessica A Kilgore

4

1 reference

15 August 2017

Joseph S Bair

5

1 reference

15 August 2017

Long-Shan Li

6

1 reference

15 August 2017

Malina Patel

7

1 reference

15 August 2017

Elizabeth I Parkinson

8

1 reference

15 August 2017

Yiguang Wang

9

1 reference

15 August 2017

Noelle S Williams

10

1 reference

15 August 2017

Jinming Gao

11

1 reference

15 August 2017

Paul J Hergenrother

12

1 reference

15 August 2017

David A Boothman

13

1 reference

15 August 2017

language of work or name

English

0 references

publication date

24 April 2012

1 reference

15 August 2017

1 reference

15 August 2017

72

1 reference

15 August 2017

12

1 reference

15 August 2017

3038-3047

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4795165/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Towards novel paradigms for cancer therapy.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Beta-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Upregulation of NAD(P)H:quinone oxidoreductase by radiation potentiates the effect of bioreductive beta-lapachone on cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Bioreductive drugs: from concept to clinic

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Development of beta-lapachone prodrugs for therapy against human cancer cells with elevated NAD(P)H:quinone oxidoreductase 1 levels.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

DT-diaphorase: a target for new anticancer drugs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Induction of NQO1 in cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Cytotoxicity and apoptosis of benzoquinones: redox cycling, cytochrome c release, and BAD protein expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

NAD(P)H: quinone oxidoreductase 1 expression in human bone marrow endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

NAD(P)H:Quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

DT-diaphorase and cytochrome B5 reductase in human lung and breast tumours

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Calcium is a key signaling molecule in beta-lapachone-mediated cell death

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Immunological quantitation of DT-diaphorase in carcinoma cell lines and clinical colon cancers: advanced tumors express greater levels of DT-diaphorase.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Phase II and pharmacokinetic study of aziridinylbenzoquinone [2,5-diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone, diaziquone, NSC 182986] in high-grade gliomas.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4795165

Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22532167

12 December 2020

inferred from PubMed ID database lookup

Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22532167

12 December 2020

inferred from PubMed ID database lookup

Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22532167

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/0008-5472.CAN-11-3135

1 reference

release_6nb3obgbozfdvab5i4bos7xjiy

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6nb3obgbozfdvab5i4bos7xjiy

24 November 2022

mapped directly with Wikidata item

1 reference

15 August 2017

PubMed publication ID

22532167

1 reference