(Q36698889)

English

Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition

scientific article published on 7 December 2012

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scholarly article

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Europe PubMed Central

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19 February 2020

Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition (English)

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19 February 2020

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Vasilis Vasiliou

2

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19 February 2020

Sophie Rahuel-Clermont

5

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19 February 2020

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Raphaël Bchini

1

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19 February 2020

Guy Branlant

3

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19 February 2020

François Talfournier

4

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19 February 2020

publication date

7 December 2012

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19 February 2020

Chemico-biological Interactions

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19 February 2020

202

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19 February 2020

1-3

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19 February 2020

78-84

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19 February 2020

Emerging roles for retinoids in regeneration and differentiation in normal and disease states

1 reference

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30 September 2017

Physiological insights into all-trans-retinoic acid biosynthesis

1 reference

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30 September 2017

Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models

1 reference

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30 September 2017

Crystallographic evidence for active-site dynamics in the hydrolytic aldehyde dehydrogenases. Implications for the deacylation step of the catalyzed reaction.

1 reference

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30 September 2017

Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes

1 reference

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30 September 2017

Between death and survival: retinoic acid in regulation of apoptosis

1 reference

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30 September 2017

Comparative expression profiling reveals an essential role for raldh2 in epimorphic regeneration

1 reference

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30 September 2017

Stabilization and conformational isomerization of the cofactor during the catalysis in hydrolytic ALDHs

1 reference

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30 September 2017

Medium- and short-chain dehydrogenase/reductase gene and protein families : Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Retinoic acid synthesis and signaling during early organogenesis

1 reference

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30 September 2017

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

1 reference

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30 September 2017

Retinoic acid in the development, regeneration and maintenance of the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Role of retinoic acid in the differentiation of embryonal carcinoma and embryonic stem cells

1 reference

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30 September 2017

The first crystal structure of a thioacylenzyme intermediate in the ALDH family: new coenzyme conformation and relevance to catalysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Protein production by auto-induction in high density shaking cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Signaling pathways in retinoid chemoprevention and treatment of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

The promise of retinoids to fight against cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

The structure of retinal dehydrogenase type II at 2.7 A resolution: implications for retinal specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

30 September 2017

Kinetics of Sheep-Liver Cytoplasmic Aldehyde Dehydrogenase

1 reference

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Adenine binding mode is a key factor in triggering the early release of NADH in coenzyme A-dependent methylmalonate semialdehyde dehydrogenase

1 reference

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Thermal destabilization of non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans upon phosphate binding in the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

5 September 2018

A disorder to order transition accompanies catalysis in retinaldehyde dehydrogenase type II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

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Multiple conformations of NAD and NADH when bound to human cytosolic and mitochondrial aldehyde dehydrogenase

1 reference

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Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602353

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23220587

12 December 2020

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inferred from PubMed ID database lookup

Mechanism of inhibition of aldehyde dehydrogenase by citral, a retinoid antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/23220587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the chemical activation of essential cys-302 upon cofactor binding to nonphosphorylating glyceraldehyde 3-phosphate dehydrogenase from Streptococcus mutans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23220587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glutamate-268 in the catalytic mechanism of nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23220587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinol metabolism in LLC-PK1 Cells. Characterization of retinoic acid synthesis by an established mammalian cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/23220587

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based on heuristic

inferred from PubMed ID database lookup

Interactions with retinol and retinoids of bovine cellular retinol-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23220587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CBI.2012.11.019

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23220587%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PMC publication ID

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Europe PubMed Central

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19 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23220587%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

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