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Leptin therapy, insulin sensitivity, and glucose homeostasis.
scientific article published on December 2012
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Europe PubMed Central
PMCID
3602983
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
title
Leptin therapy, insulin sensitivity, and glucose homeostasis
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3602983
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
author
Claudio A. Mastronardi
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2
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Europe PubMed Central
PMCID
3602983
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
Julio Licinio
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4
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Europe PubMed Central
PMCID
3602983
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
author name string
Gilberto Paz-Filho
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1
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Europe PubMed Central
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3602983
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
Ma-Li Wong
series ordinal
3
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Europe PubMed Central
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3602983
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28 February 2020
publication date
1 December 2012
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Europe PubMed Central
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3602983
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
published in
Indian Journal of Endocrinology and Metabolism
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stated in
Europe PubMed Central
PMCID
3602983
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
volume
16
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Europe PubMed Central
PMCID
3602983
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
issue
Suppl 3
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3602983
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28 February 2020
page(s)
S549-55
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Europe PubMed Central
PMCID
3602983
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
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Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility
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30 September 2017
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
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Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction
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30 September 2017
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Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin,
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30 September 2017
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30 September 2017
Congenital leptin deficiency is associated with severe early-onset obesity in humans
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30 September 2017
Leptin impairs metabolic actions of insulin in isolated rat adipocytes.
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30 September 2017
Relatively low plasma leptin concentrations precede weight gain in Pima Indians
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30 September 2017
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
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Efficacy of leptin therapy in the different forms of human lipodystrophy
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28 June 2018
Prevalence of hepatic steatosis after islet transplantation and its relation to graft function
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28 June 2018
High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells
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28 June 2018
Central infusion of leptin improves insulin resistance and suppresses beta-cell function, but not beta-cell mass, primarily through the sympathetic nervous system in a type 2 diabetic rat model
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5 September 2018
A new link between skeleton, obesity and insulin resistance: relationships between osteocalcin, leptin and insulin resistance in obese children before and after weight loss
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5 September 2018
An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion
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5 September 2018
Central leptin action improves skeletal muscle AKT, AMPK, and PGC1 alpha activation by hypothalamic PI3K-dependent mechanism
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5 September 2018
Deconvolution of insulin secretion, insulin hepatic extraction post-hepatic delivery rates and sensitivity during 24-hour standardized meals: time course of glucose homeostasis in leptin replacement treatment
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5 September 2018
Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy.
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5 September 2018
The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.
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retrieved
5 September 2018
Long-term efficacy of leptin replacement in patients with generalized lipodystrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
Insulin-resistant patients with type 2 diabetes mellitus have higher serum leptin levels independently of body fat mass
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
Leptin directly stimulates thermogenesis in skeletal muscle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
Leptin-replacement therapy for lipodystrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
A leptin missense mutation associated with hypogonadism and morbid obesity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
Leptin: a review of its peripheral actions and interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
5 September 2018
The Body-Mass Index of Twins Who Have Been Reared Apart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602983
retrieved
4 December 2018
Leptin concentrations and insulin sensitivity in normoglycemic men
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23565489
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23565489
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23565489
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Leptin and diabetes in lipoatrophic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23565489
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4103/2230-8210.105571
1 reference
stated in
Europe PubMed Central
PMCID
3602983
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
PMCID
3602983
1 reference
stated in
Europe PubMed Central
PMCID
3602983
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
PubMed ID
23565489
1 reference
stated in
Europe PubMed Central
PMCID
3602983
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23565489%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
ResearchGate publication ID
236130086
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