(Q36708210)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia (English)

1 reference

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12 March 2020

3

1 reference

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12 March 2020

8

Hemmen Sabir

1 reference

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12 March 2020

9

Marianne Thoresen

1 reference

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12 March 2020

author name string

Thomas Wood

1

1 reference

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12 March 2020

Damjan Osredkar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Elke Maes

4

1 reference

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12 March 2020

Mari Falck

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Torun Flatebø

6

1 reference

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12 March 2020

Lars Walløe

7

1 reference

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12 March 2020

language of work or name

English

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publication date

21 March 2016

1 reference

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12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

6

1 reference

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12 March 2020

page(s)

23430

1 reference

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Creative Commons Attribution 4.0 International

12 March 2020

copyright license

start time

1 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4800445/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/srep23430

0 references

cites work

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1 reference

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Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury.

30 September 2017

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Sex differences in behavioral outcomes following temperature modulation during induced neonatal hypoxic ischemic injury in rats

30 September 2017

1 reference

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Therapeutic hypothermia and hypoxia-ischemia in the term-equivalent neonatal rat: characterization of a translational preclinical model.

30 September 2017

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Animal studies of neonatal hypothermic neuroprotection have translated well in to practice

30 September 2017

1 reference

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Hypoxia-ischemia and therapeutic hypothermia in the neonatal mouse brain--a longitudinal study

30 September 2017

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Who should we cool after perinatal asphyxia?

30 September 2017

1 reference

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How long is too long for cerebral cooling after ischemia in fetal sheep?

30 September 2017

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Rewarming from therapeutic hypothermia induces cortical neuron apoptosis in a swine model of neonatal hypoxic-ischemic encephalopathy

30 September 2017

1 reference

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Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial

30 September 2017

1 reference

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Physiological responses to hypothermia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Brain cell death is reduced with cooling by 3.5°C to 5°C but increased with cooling by 8.5°C in a piglet asphyxia model

30 September 2017

1 reference

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Mechanisms of hypothermic neuroprotection.

30 September 2017

1 reference

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Sex differences in behavioral outcome following neonatal hypoxia ischemia: insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic brain injury

30 September 2017

1 reference

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Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy

30 September 2017

1 reference

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Targeted temperature management at 33°C versus 36°C after cardiac arrest

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Docosahexaenoic acid augments hypothermic neuroprotection in a neonatal rat asphyxia model

30 September 2017

1 reference

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Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

30 September 2017

1 reference

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Cooling for newborns with hypoxic ischaemic encephalopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrest

30 September 2017

1 reference

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Neuroprotective mechanisms of hypothermia in brain ischaemia

30 September 2017

1 reference

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Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Persisting mild hypothermia suppresses hypoxia-inducible factor-1alpha protein synthesis and hypoxia-inducible factor-1-mediated gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

The role and regulation of hypoxia-inducible factor-1alpha expression in brain development and neonatal hypoxic-ischemic brain injury

30 September 2017

1 reference

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Elevated temperature after hypoxic-ischemic encephalopathy: risk factor for adverse outcomes

30 September 2017

1 reference

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Hypothermic neuroprotection.

30 September 2017

1 reference

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Neonatal brain protection and deep hypothermic circulatory arrest: pathophysiology of ischemic neuronal injury and protective strategies.

30 September 2017

1 reference

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The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis

30 September 2017

1 reference

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Hyperthermia after cardiac arrest is associated with an unfavorable neurologic outcome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Rat model of perinatal hypoxic-ischemic brain damage

30 September 2017

1 reference

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Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs

30 September 2017

1 reference

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Posthypoxic cooling of neonatal rats provides protection against brain injury

30 September 2017

1 reference

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Broccoli sprout supplementation during pregnancy prevents brain injury in the newborn rat following placental insufficiency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia model.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Effect of hypothermic post-treatment on hypoxic-ischemic striatal injury, and normal striatal development, in neonatal rats: a stereological study

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Protective effects of moderate hypothermia after neonatal hypoxia-ischemia: short- and long-term outcome

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Modest hypothermia preserves cerebral energy metabolism during hypoxia-ischemia and correlates with brain damage: a 31P nuclear magnetic resonance study in unanesthetized neonatal rats.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Influence of age on the cerebral lesions in an immature rat model of cerebral hypoxia-ischemia: a light microscopic study.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Beneficial effect of mild hypothermia and detrimental effect of deep hypothermia after cardiac arrest in dogs

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Helium preconditioning protects against neonatal hypoxia-ischemia via nitric oxide mediated up-regulation of antioxidases in a rat model.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

The neuroprotection of hypoxic preconditioning on rat brain against traumatic brain injury by up-regulated transcription factor Nrf2 and HO-1 expression.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

The effect of resuscitation in 100% oxygen on brain injury in a newborn rat model of severe hypoxic-ischaemic encephalopathy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

The feasibility of using a portable xenon delivery device to permit earlier xenon ventilation with therapeutic cooling of neonates during ambulance retrieval.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Melatonin use for neuroprotection in perinatal asphyxia: a randomized controlled pilot study.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Effects of hypothermia for perinatal asphyxia on childhood outcomes.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Sex differences in behavioral outcome following neonatal hypoxia ischemia: Insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic injury.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Hypothermia at 35 °C reduces the time-dependent microglial production of pro-inflammatory and anti-inflammatory factors that mediate neuronal cell death.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Immediate hypothermia is not neuroprotective after severe hypoxia-ischemia and is deleterious when delayed by 12 hours in neonatal rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Resuscitation with 100% oxygen increases injury and counteracts the neuroprotective effect of therapeutic hypothermia in the neonatal rat.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Xenon preconditioning confers neuroprotection regardless of gender in a mouse model of transient middle cerebral artery occlusion

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Moderate hypothermia to treat perinatal asphyxial encephalopathy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Cooling combined with immediate or delayed xenon inhalation provides equivalent long-term neuroprotection after neonatal hypoxia-ischemia.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Weight and Body Temperature

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

"Therapeutic time window" duration decreases with increasing severity of cerebral hypoxia-ischaemia under normothermia and delayed hypothermia in newborn piglets

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Preventing hyperthermia decreases brain damage following neonatal hypoxic-ischemic seizures

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Hypothermia augments reactive oxygen species detected in the guinea pig isolated perfused heart

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Increased injury following intermittent fetal hypoxia-reoxygenation is associated with increased free radical production in fetal rabbit brain.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Posthypoxic hypothermia in newborn piglets.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

The stress of being restrained reduces brain damage after a hypoxic-ischaemic insult in the 7-day-old rat.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Modest hypothermia provides partial neuroprotection for ischemic neonatal brain.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4800445

Part 11: Neonatal Resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP23430

Ontogeny of homeothermy in the immature rat: metabolic and thermal responses

21 January 2018

1 reference

12 December 2020

Improved neuroprotection with hypothermia delayed by 6 hours following cerebral hypoxia-ischemia in the 14-day-old rat

1 reference

12 December 2020

Effect of ambient temperature on rectal temperature in normal and malnourished rats during early postnatal development

1 reference

12 December 2020

Influence of mild hypothermia on hypoxic-ischemic brain damage in the immature rat

1 reference

12 December 2020

Rectal temperature in the newborn after birth asphyxia

1 reference

12 December 2020

The influence of immaturity on hypoxic‐ischemic brain damage in the rat

1 reference

12 December 2020

Huddling by rat pups: group behavioral mechanisms of temperature regulation and energy conservation

1 reference

12 December 2020

Maturation of tempeature homeostasis in the rat

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP23430

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26997257%20AND%20SRC:MED&resulttype=core&format=json