(Q36709139)

English

Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

scientific article published on 10 January 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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neurodegeneration

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based on heuristic

inferred from title

object named as

Zoe N Ludlow

7

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Danielle Diaper

object named as

Danielle C Diaper

1

0 references

object named as

Ben Sutcliffe

3

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object named as

Frank Hirth

14

0 references

Ammar Al-Chalabi

object named as

Ammar Al-Chalabi

11

0 references

Christopher Shaw

object named as

Christopher E Shaw

12

0 references

Patrick Callaerts

9

object named as

Patrick Callaerts

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Christopher J. H. Elliott

5

object named as

Christopher J H Elliott

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Yoshitsugu Adachi

2

1 reference

Europe PubMed Central

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15 August 2017

Dickon M Humphrey

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Alan Stepto

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Lies Vanden Broeck

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Bart Dermaut

10

1 reference

Europe PubMed Central

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15 August 2017

Iain M Robinson

13

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Europe PubMed Central

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15 August 2017

language of work or name

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publication date

10 January 2013

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Europe PubMed Central

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15 August 2017

Human Molecular Genetics

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Europe PubMed Central

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15 August 2017

22

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1539-1557

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3605831/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605831

30 September 2017

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

1 reference

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30 September 2017

Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605831

30 September 2017

In vivo measurement of muscle output in intact Drosophila.

1 reference

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30 September 2017

The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

1 reference

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30 September 2017

RNA-binding proteins with prion-like domains in ALS and FTLD-U.

1 reference

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30 September 2017

Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.

1 reference

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30 September 2017

Neuronal function and dysfunction of Drosophila dTDP

1 reference

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30 September 2017

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

1 reference

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30 September 2017

TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization

1 reference

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30 September 2017

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605831

30 September 2017

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

1 reference

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30 September 2017

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

1 reference

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30 September 2017

The dopaminergic system in the aging brain of Drosophila

1 reference

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30 September 2017

TDP-43 regulates its mRNA levels through a negative feedback loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605831

30 September 2017

TDP-43-based animal models of neurodegeneration: new insights into ALS pathology and pathophysiology

1 reference

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30 September 2017

Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila.

1 reference

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30 September 2017

Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes

1 reference

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30 September 2017

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.

1 reference

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30 September 2017

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

1 reference

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30 September 2017

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

1 reference

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30 September 2017

The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605831

30 September 2017

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605831

30 September 2017

Drosophila melanogaster in the study of human neurodegeneration

1 reference

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30 September 2017

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

1 reference

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30 September 2017

E-RNAi: a web application for the multi-species design of RNAi reagents--2010 update

1 reference

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30 September 2017

TAR DNA-binding protein 43 in neurodegenerative disease

1 reference

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30 September 2017

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

1 reference

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30 September 2017

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

1 reference

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High-throughput ethomics in large groups of Drosophila.

1 reference

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30 September 2017

Structural insights into TDP-43 in nucleic-acid binding and domain interactions

1 reference

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30 September 2017

Structural determinants of the cellular localization and shuttling of TDP-43.

1 reference

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30 September 2017

On the origin of new genes in Drosophila

1 reference

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30 September 2017

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

1 reference

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30 September 2017

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

1 reference

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30 September 2017

TDP-43 A315T mutation in familial motor neuron disease

1 reference

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30 September 2017

TDP-43: a novel neurodegenerative proteinopathy

1 reference

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A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

1 reference

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30 September 2017

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

1 reference

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Neuronal death: where does the end begin?

1 reference

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Synaptic development: insights from Drosophila

1 reference

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

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Molecular biology of amyotrophic lateral sclerosis: insights from genetics

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Axonal self-destruction and neurodegeneration

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30 September 2017

Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.

1 reference

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5 September 2018

Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.

1 reference

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1 reference

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23307927

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23307927

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDT005

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

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