(Q36710571)

15 August 2017

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title

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy (English)

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15 August 2017

main subject

Gram-negative bacteria

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antibiotic

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author name string

Abdallah Mahamoud

1

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15 August 2017

Jacqueline Chevalier

2

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15 August 2017

Sandrine Alibert-Franco

3

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15 August 2017

Winfried V Kern

4

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15 August 2017

Jean-Marie Pagès

5

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15 August 2017

language of work or name

English

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publication date

17 January 2007

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Journal of Antimicrobial Chemotherapy

15 August 2017

published in

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15 August 2017

volume

59

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15 August 2017

issue

6

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15 August 2017

page(s)

1223-1229

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Active efflux, a common mechanism for biocide and antibiotic resistance

15 August 2017

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TolC--the bacterial exit duct for proteins and drugs.

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Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria

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Molecular basis of bacterial outer membrane permeability

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Tracing pathways of transport protein evolution

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Antibiotic efflux pumps

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Mechanisms of solvent tolerance in gram-negative bacteria

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Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415.

21 January 2018

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Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.

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Platensimycin is a selective FabF inhibitor with potent antibiotic properties

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Efflux pumps: their role in antibacterial drug discovery

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Ciprofloxacin-resistant Salmonella enterica serovar Typhimurium strains are difficult to select in the absence of AcrB and TolC

21 January 2018

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Neopeptide antibiotics that function as opsonins and membrane-permeabilizing agents for gram-negative bacteria

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Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium.

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Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

21 January 2018

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Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

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Porin alteration and active efflux: two in vivo drug resistance strategies used by Enterobacter aerogenes.

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Active efflux of bile salts by Escherichia coli

21 January 2018

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Multidrug pump inhibitors uncover remarkable activity of plant antimicrobials.

21 January 2018

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Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin

21 January 2018

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Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy

21 January 2018

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Use of an efflux pump inhibitor to determine the prevalence of efflux pump-mediated fluoroquinolone resistance and multidrug resistance in Pseudomonas aeruginosa

21 January 2018

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A periplasmic drug-binding site of the AcrB multidrug efflux pump: a crystallographic and site-directed mutagenesis study.

21 January 2018

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Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

21 January 2018

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Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

21 January 2018

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Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

21 January 2018

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The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors

21 January 2018

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Peptidomimetics of efflux pump inhibitors potentiate the activity of levofloxacin in Pseudomonas aeruginosa

21 January 2018

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MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

21 January 2018

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds

21 January 2018

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety

21 January 2018

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 5: Carbon-substituted analogues at the C-2 position

21 January 2018

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Quinoline derivatives as promising inhibitors of antibiotic efflux pump in multidrug resistant Enterobacter aerogenes isolates

21 January 2018

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New pyridoquinoline derivatives as potential inhibitors of the fluoroquinolone efflux pump in resistant Enterobacter aerogenes strains

21 January 2018

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4-alkoxy and 4-thioalkoxyquinoline derivatives as chemosensitizers for the chloramphenicol-resistant clinical Enterobacter aerogenes 27 strain

21 January 2018

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Alkylaminoquinolines inhibit the bacterial antibiotic efflux pump in multidrug-resistant clinical isolates

21 January 2018

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Inhibitors of antibiotic efflux in resistant Enterobacter aerogenes and Klebsiella pneumoniae strains

21 January 2018

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Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates.

21 January 2018

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Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus

21 January 2018

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Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux pumps

21 January 2018

1 reference

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Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli

21 January 2018

1 reference

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Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Escherichia coli

21 January 2018

1 reference

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Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKL493

Inhibition of the tetracycline efflux antiport protein by 13-thio-substituted 5-hydroxy-6-deoxytetracyclines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKL493

Molecular requirements for the inhibition of the tetracycline antiport protein and the effect of potent inhibitors on the growth of tetracycline-resistant bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKL493

21 January 2018

Identifiers

DOI

10.1093/JAC/DKL493

1 reference

15 August 2017

1 reference