(Q36711234)

15 August 2017

Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response (English)

1 reference

15 August 2017

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Lawrence B Gardner

1

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language of work or name

English

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publication date

24 March 2008

1 reference

Molecular and Cellular Biology

15 August 2017

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15 August 2017

28

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15 August 2017

11

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15 August 2017

3729-3741

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PMC publication ID

2423288

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2423288/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Pioneer round of translation occurs during serum starvation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

The efficiency of nonsense-mediated mRNA decay is an inherent character and varies among different cells

30 September 2017

1 reference

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Alternative splicing and nonsense-mediated mRNA decay in the regulation of a new adenomatous polyposis coli transcript.

30 September 2017

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Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy

30 September 2017

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Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias

30 September 2017

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Hypoxic regulation of Id-1 and activation of the unfolded protein response are aberrant in neuroblastoma.

30 September 2017

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Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

30 September 2017

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Endoplasmic reticulum stress signaling in disease

30 September 2017

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Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.

30 September 2017

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Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast

30 September 2017

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Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges

30 September 2017

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Targeting of aberrant mRNAs to cytoplasmic processing bodies

30 September 2017

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30 September 2017

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ARE-mRNA degradation requires the 5'-3' decay pathway.

30 September 2017

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Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

30 September 2017

1 reference

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

30 September 2017

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Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Cellular reaction to hypoxia: sensing and responding to an adverse environment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Activating transcription factor 4 is translationally regulated by hypoxic stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Regulation of transcription and translation by hypoxia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Transcriptional and translational control in the Mammalian unfolded protein response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Regulated translation initiation controls stress-induced gene expression in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Nonsense-mediated mRNA decay in health and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Infrequent translation of a nonsense codon is sufficient to decrease mRNA level

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

beta zero thalassemia in Sardinia is caused by a nonsense mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

A regulatory mechanism that detects premature nonsense codons in T-cell receptor transcripts in vivo is reversed by protein synthesis inhibitors in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

mRNA made during heat shock enters the first round of translation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2423288

Hypoxia inhibits G1/S transition through regulation of p27 expression

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18362164

12 December 2020

inferred from PubMed ID database lookup

The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18362164

12 December 2020

inferred from PubMed ID database lookup

Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18362164

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.02284-07

1 reference

15 August 2017

1 reference

PMC publication ID

2423288

15 August 2017

PubMed publication ID

18362164

1 reference

PMC publication ID

2423288