(Q36716538)

15 August 2017

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title

Particle engineering for pulmonary drug delivery (English)

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15 August 2017

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Albert H L Chow

1

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15 August 2017

Henry H Y Tong

series ordinal

2

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15 August 2017

Pratibhash Chattopadhyay

series ordinal

3

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15 August 2017

Boris Y Shekunov

series ordinal

4

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15 August 2017

publication date

1 March 2007

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15 August 2017

published in

Pharmaceutical Research

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15 August 2017

volume

24

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15 August 2017

issue

3

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15 August 2017

page(s)

411-437

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Quantification of the surface morphologies of lactose carriers and their effect on the in vitro deposition of salbutamol sulphate.

15 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9174-3

Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems

21 January 2018

1 reference

12 December 2020

Evaluation of atomizer performance in production of respirable spray-dried particles

1 reference

12 December 2020

Characterization of suspension-based metered dose inhaler formulations composed of spray-dried budesonide microcrystals dispersed in HFA-134a

1 reference

12 December 2020

Aerosolisation of beclomethasone dipropionate using spray dried lactose/polyethylene glycol carriers

1 reference

12 December 2020

Liposomal amikacin dry powder inhaler: effect of fines on in vitro performance

1 reference

12 December 2020

Activity-stability considerations of trypsinogen during spray drying: effects of sucrose

1 reference

12 December 2020

Sustained bronchodilation with isoproterenol poly(glycolide-co-lactide) microspheres

1 reference

12 December 2020

Use of inverse gas chromatography (IGC) to determine the surface energy and surface area of powdered materials

1 reference

12 December 2020

Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats

1 reference

12 December 2020

Influenza vaccine powder formulation development: spray-freeze-drying and stability evaluation

1 reference

12 December 2020

Precipitation of proteins in supercritical carbon dioxide

1 reference

12 December 2020

Optimisation of powders for pulmonary delivery using supercritical fluid technology

1 reference

12 December 2020

Preparation and characterisation of hydrocortisone particles using a supercritical fluids extraction process.

1 reference

12 December 2020

Alternative sugars as potential carriers for dry powder inhalations

1 reference

12 December 2020

Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: manufacture and characterization

1 reference

12 December 2020

Inhalable microparticles containing drug combinations to target alveolar macrophages for treatment of pulmonary tuberculosis

1 reference

12 December 2020

Physical stability of salmon calcitonin spray-dried powders for inhalation

1 reference

12 December 2020

Conditioning following powder micronization: influence on particle growth of salbutamol sulfate

1 reference

12 December 2020

The use of amino acids to enhance the aerosolisation of spray-dried powders for pulmonary gene therapy

1 reference

12 December 2020

The influence of sodium glycocholate and other additives on the in vivo transfection of plasmid DNA in the lungs

1 reference

12 December 2020

The formation of plasmid DNA loaded pharmaceutical powders using supercritical fluid technology

1 reference

12 December 2020

Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres

1 reference

12 December 2020

Poly(lactide-co-glycolide) microsphere formulations of darbepoetin alfa: spray drying is an alternative to encapsulation by spray-freeze drying

1 reference

12 December 2020

Characterisation and deposition studies of engineered lactose crystals with potential for use as a carrier for aerosolised salbutamol sulfate from dry powder inhalers

1 reference

12 December 2020

Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying.

1 reference

12 December 2020

Spray-drying of trypsin - surface characterisation and activity preservation.

1 reference

12 December 2020

Biopharmaceutical powders: particle formation and formulation considerations

1 reference

12 December 2020

Characterization of two polymorphs of salmeterol xinafoate crystallized from supercritical fluids

1 reference

12 December 2020

Insulin microcrystal suspension as a long-acting formulation for pulmonary delivery

1 reference

12 December 2020

Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres

1 reference

12 December 2020

The use of lactose recrystallised from carbopol gels as a carrier for aerosolised salbutamol sulphate

1 reference

12 December 2020

Sustained release of insulin from sodium hyaluronate based dry powder formulations after pulmonary delivery to beagle dogs

1 reference

12 December 2020

Hydrophobic ion pairing of isoniazid using a prodrug approach

1 reference

12 December 2020

Characterization of tolbutamide polymorphs (Burger's forms II and IV) and polymorphic transition behavior.

1 reference

12 December 2020

The effect of water to ethanol feed ratio on physical properties and aerosolization behavior of spray dried cromolyn sodium particles

1 reference

12 December 2020

Effect of surface layering time of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate

1 reference

12 December 2020

Stable amorphous danazol nanostructured powders with rapid dissolution rates produced by spray freezing into liquid

1 reference

12 December 2020

Formulation factors in preparing BTM-chitosan microspheres by spray drying method

1 reference

12 December 2020

Poly(ether-anhydride) dry powder aerosols for sustained drug delivery in the lungs

1 reference

12 December 2020

Physicochemical factors governing the performance of nedocromil sodium as a dry powder aerosol.

1 reference

12 December 2020

The influence of carrier morphology on drug delivery by dry powder inhalers.

1 reference

12 December 2020

Affinity scale between a carrier and a drug in DPI studied by atomic force microscopy.

1 reference

12 December 2020

The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers.

1 reference

12 December 2020

Pulmonary delivery of therapeutic peptides via dry powder inhalation: effects of micronisation and manufacturing

1 reference

12 December 2020

Aerosolization properties, surface composition and physical state of spray-dried protein powders

1 reference

12 December 2020

Microencapsulated chitosan nanoparticles for lung protein delivery

1 reference

12 December 2020

Nanoparticle technology for drug delivery: from nanoparticles to cutting-edge delivery strategies - part I

1 reference

12 December 2020

Dry powder inhalation of liposomal Ketotifen fumarate: formulation and characterization

1 reference

12 December 2020

Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized anti-IgE monoclonal antibody

1 reference

12 December 2020

Preparation and characterization of microparticles containing peptide produced by a novel process: spray freezing into liquid

1 reference

12 December 2020

Surface-modified antiasthmatic dry powder aerosols inhaled intratracheally reduce the pharmacologically effective dose

1 reference

12 December 2020

Comparison of powder produced by evaporative precipitation into aqueous solution (EPAS) and spray freezing into liquid (SFL) technologies using novel Z-contrast STEM and complimentary techniques

1 reference

12 December 2020

Nanoparticles of poorly water-soluble drugs prepared by supercritical fluid extraction of emulsions

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12 December 2020

Optimization of a dry powder inhaler formulation of nacystelyn, a new mucoactive agent

1 reference

12 December 2020

Dry powder aerosol delivery systems: current and future research directions

1 reference

12 December 2020

Spray-drying performance of a bench-top spray dryer for protein aerosol powder preparation

1 reference

12 December 2020

Protein powders for encapsulation: a comparison of spray-freeze drying and spray drying of darbepoetin alfa

1 reference

12 December 2020

Characterization of a surface modified dry powder inhalation carrier prepared by "particle smoothing".

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12 December 2020

Emulsions containing partially water-miscible solvents for the preparation of drug nanosuspensions

1 reference

12 December 2020

Effect of powder polydispersity on aerosol generation.

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12 December 2020

Poly-(D,L-lactic acid) microspheres incorporating histological dyes for intra-pulmonary histopathological investigations

1 reference

12 December 2020

Rapid dissolving high potency danazol powders produced by spray freezing into liquid process

1 reference

12 December 2020

A new powder design method to improve inhalation efficiency of pranlukast hydrate dry powder aerosols by surface modification with hydroxypropylmethylcellulose phthalate nanospheres

1 reference

12 December 2020

Effects of carriers and storage of formulation on the lung deposition of a hydrophobic and hydrophilic drug from a DPI.

1 reference

12 December 2020

Airways delivery of rifampicin microparticles for the treatment of tuberculosis

1 reference

12 December 2020

The effect of vehicle on physical properties and aerosolisation behaviour of disodium cromoglycate microparticles spray dried alone or with L-leucine

1 reference

12 December 2020

How much particle surface corrugation is sufficient to improve aerosol performance of powders?

1 reference

12 December 2020

Preparation of polymeric submicron particle-containing microparticles using a 4-fluid nozzle spray drier

1 reference

12 December 2020

Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolization

1 reference

12 December 2020

Micronized powders of a poorly water soluble drug produced by a spray-freezing into liquid-emulsion process

1 reference

12 December 2020

Thermal analysis of trace levels of polymorphic impurity in salmeterol xinafoate samples

1 reference

12 December 2020

In vitro characterization of jet-milled and in-situ-micronized fluticasone-17-propionate

1 reference

12 December 2020

Physicochemical characterization of spray-dried phenylbutazone polymorphs

1 reference

12 December 2020

Physicochemical characterization of a new respirable form of nedocromil.

1 reference

12 December 2020

Polymorphic properties of micronized carbamazepine produced by RESS.

1 reference

12 December 2020

Solution-based particle formation of pharmaceutical powders by supercritical or compressed fluid CO2 and cryogenic spray-freezing technologies

1 reference

12 December 2020

Systemic delivery of parathyroid hormone (1-34) using inhalation dry powders in rats

1 reference

12 December 2020

Ultrasonic atomisation into reduced pressure atmosphere--envisaging aseptic spray-drying for microencapsulation.

1 reference

12 December 2020

Particle size analysis in pharmaceutics: principles, methods and applications

1 reference

12 December 2020

The effect of operating and formulation variables on the morphology of spray-dried protein particles

1 reference

12 December 2020

Glycine crystallization during spray drying: the pH effect on salt and polymorphic forms

1 reference

12 December 2020

The use of different sugars as fine and coarse carriers for aerosolised salbutamol sulphate

1 reference

12 December 2020

Enhanced dispersibility and deposition of spray-dried powders for pulmonary gene therapy

1 reference

12 December 2020

Modifying the release of leuprolide from spray dried OED microparticles

1 reference

12 December 2020

Lactose modifications enhance its drug performance in the novel multiple dose Taifun DPI.

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12 December 2020

Enhanced pulmonary absorption following aerosol administration of mucoadhesive powder microspheres

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12 December 2020

A novel spray-drying technique to produce low density particles for pulmonary delivery

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12 December 2020

Improvement of insulin absorption from intratracheally administrated dry powder prepared by supercritical carbon dioxide process

1 reference

12 December 2020

Technosphere/Insulin--a new approach for effective delivery of human insulin via the pulmonary route

1 reference

12 December 2020

Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs.

1 reference

12 December 2020

Improved lung delivery from a passive dry powder inhaler using an Engineered PulmoSphere powder

1 reference

12 December 2020

Particle Characteristics and Lung Deposition Patterns in a Human Airway Replica of a Dry Powder Formulation of Polylactic Acid Produced Using Supercritical Fluid Technology

1 reference

12 December 2020

Effect of amino acids on the dispersion of disodium cromoglycate powders

1 reference

12 December 2020

Protein deposition from dry powder inhalers: fine particle multiplets as performance modifiers

1 reference

12 December 2020

Hollow porous particles in metered dose inhalers

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12 December 2020

Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system

1 reference

12 December 2020

Particle interactions involved in aerosol dispersion of ternary interactive mixtures

1 reference

12 December 2020

In-situ-micronization of disodium cromoglycate for pulmonary delivery

1 reference

12 December 2020

Evaluation of microparticles containing doxorubicin suitable for aerosol delivery to the lungs.

1 reference

12 December 2020

Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung

1 reference

12 December 2020

Nebulization of NanoCrystals: production of a respirable solid-in-liquid-in-air colloidal dispersion

1 reference

12 December 2020

Spray freezing into liquid nitrogen for highly stable protein nanostructured microparticles

1 reference

12 December 2020

Spray-freeze-drying for protein powder preparation: particle characterization and a case study with trypsinogen stability

1 reference

12 December 2020

Evaluation of novel aerosol formulations designed for mucosal vaccination against influenza virus

1 reference

12 December 2020

New polymeric carriers for controlled drug delivery following inhalation or injection

1 reference

12 December 2020

Release mechanism of insulin encapsulated in trehalose ester derivative microparticles delivered via inhalation

1 reference

12 December 2020

Nanosuspensions in drug delivery

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12 December 2020

The use of absorption enhancers to enhance the dispersibility of spray-dried powders for pulmonary gene therapy.

1 reference

12 December 2020

Protein inhalation powders: spray drying vs spray freeze drying

1 reference

12 December 2020

Improvement of stability and absorbability of dry insulin powder for inhalation by powder-combination technique

1 reference

12 December 2020

Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance

1 reference

12 December 2020

Droplet and particle size relationship and shell thickness of inhalable lactose particles during spray drying

1 reference

12 December 2020

Influence of particle size, air flow, and inhaler device on the dispersion of mannitol powders as aerosols

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12 December 2020

Ultrafine particle-lung interactions: does size matter?

1 reference

12 December 2020

Supercritical fluids crystallization of budesonide and flunisolide

1 reference

12 December 2020

Modulation of rifampicin release from spray-dried microspheres using combinations of poly-(DL-lactide)

1 reference

12 December 2020

Inhalation of estradiol for sustained systemic delivery

1 reference

12 December 2020

The influence of carrier and drug morphology on drug delivery from dry powder formulations

1 reference

12 December 2020

Large porous particles for pulmonary drug delivery

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12 December 2020

Evolution of dry powder inhaler design, formulation, and performance

1 reference

12 December 2020

Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders

1 reference

12 December 2020

Liposomes and disaccharides as carriers in spray-dried powder formulations of superoxide dismutase

1 reference

12 December 2020

Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability

1 reference

12 December 2020

Novel sustained release microspheres for pulmonary drug delivery

1 reference

12 December 2020

The effect of process variables on the degradation and physical properties of spray dried insulin intended for inhalation

1 reference

12 December 2020

Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres

1 reference

12 December 2020

Effect of particle morphology on the triboelectrification in dry powder inhalers

1 reference

12 December 2020

Solubility and precipitation of nicotinic acid in supercritical carbon dioxide

1 reference

12 December 2020

Protein spray-freeze drying. Effect of atomization conditions on particle size and stability

1 reference

12 December 2020

Controlled dissolution from wax-coated aerosol particles in canine lungs.

1 reference

12 December 2020

The influence of carrier roughness on adhesion, content uniformity and the in vitro deposition of terbutaline sulphate from dry powder inhalers

1 reference

12 December 2020

Use of solid corrugated particles to enhance powder aerosol performance.

1 reference

12 December 2020

Fundamental effects of particle morphology on lung delivery: predictions of Stokes' law and the particular relevance to dry powder inhaler formulation and development

1 reference

12 December 2020

Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs

1 reference

12 December 2020

Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology.

1 reference

12 December 2020

The role of particle engineering in relation to formulation and de-agglomeration principle in the development of a dry powder formulation for inhalation of cetrorelix.

1 reference

12 December 2020

Reduction of structural perturbations in bovine serum albumin by non-aqueous microencapsulation

1 reference

12 December 2020

Lactose as a carrier in dry powder formulations: the influence of surface characteristics on drug delivery.

1 reference

12 December 2020

In vivo lung deposition of hollow porous particles from a pressurized metered dose inhaler

1 reference

12 December 2020

Particle size and density in spray drying-effects of carbohydrate properties

1 reference

12 December 2020

The characteristics of betamethasone-loaded chitosan microparticles by spray-drying method

1 reference

12 December 2020

Preparation of dry powder inhalation by surface treatment of lactose carrier particles

1 reference

12 December 2020

Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.

1 reference

12 December 2020

Preparation of dry powder inhalation with lactose carrier particles surface-coated using a Wurster fluidized bed.

1 reference

12 December 2020

Improved inhalation behavior of steroid KSR-592 in vitro with Jethaler by polymorphic transformation to needle-like crystals (beta-form).

1 reference

12 December 2020

Immobilization of fine particles on lactose carrier by precision coating and its effect on the performance of dry powder formulations

1 reference

12 December 2020

Influence of polymorphism on the surface energetics of salmeterol xinafoate crystallized from supercritical fluids

1 reference

12 December 2020

Micron-size drug particles: common and novel micronization techniques

1 reference

12 December 2020

Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: spray-freezing into liquid with atmospheric freeze-drying.

1 reference

12 December 2020

Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery

1 reference

12 December 2020

Effect of additives on insulin absorption from intratracheally administered dry powders in rats

1 reference

12 December 2020

Effect of surface covering of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate

1 reference

12 December 2020

Predicting the aerosol performance of dry powder inhalation formulations by interparticulate interaction analysis using inverse gas chromatography

1 reference

12 December 2020

Formulation and physical characterization of large porous particles for inhalation

1 reference

12 December 2020

Preparation of DNA dry powder for non-viral gene delivery by spray-freeze drying: effect of protective agents (polyethyleneimine and sugars) on the stability of DNA.

1 reference

12 December 2020

Protein formulation and lyophilization cycle design: prevention of damage due to freeze-concentration induced phase separation

1 reference

12 December 2020

Theophylline particle design using chitosan by the spray drying

1 reference

12 December 2020

Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release

1 reference

12 December 2020

Generation of micro-particles of proteins for aerosol delivery using high pressure modified carbon dioxide

1 reference

12 December 2020

Micronization of anti-inflammatory drugs for pulmonary delivery by a controlled crystallization process

1 reference

12 December 2020

Drug encapsulation using supercritical fluid extraction of emulsions

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12 December 2020

Ciprofloxacin-loaded bovine serum albumin microspheres: preparation and drug-release in vitro

1 reference

12 December 2020

10.1007/S11095-006-9174-3

Identifiers

DOI

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15 August 2017

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