(Q41610659)

5 October 2017

title

Activity-stability considerations of trypsinogen during spray drying: effects of sucrose (English)

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5 October 2017

Tzannis ST

1

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5 October 2017

Prestrelski SJ

series ordinal

2

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5 October 2017

language of work or name

English

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publication date

1 March 1999

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Journal of Pharmaceutical Sciences

5 October 2017

published in

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5 October 2017

volume

88

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5 October 2017

issue

3

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5 October 2017

page(s)

351-359

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New methods of drug delivery

5 October 2017

cites work

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7 January 2021

Pulmonary delivery of peptide drugs: effect of particle size on bioavailability of leuprolide acetate in healthy male volunteers

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7 January 2021

Solid-state stability of human insulin. II. Effect of water on reactive intermediate partitioning in lyophiles from pH 2-5 solutions: stabilization against covalent dimer formation

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7 January 2021

Moisture-induced aggregation of lyophilized proteins in the solid state

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7 January 2021

Feasibility study on spray-drying protein pharmaceuticals: recombinant human growth hormone and tissue-type plasminogen activator.

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7 January 2021

Precipitation of proteins in supercritical carbon dioxide

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7 January 2021

Coprecipitation of enzymes with water soluble starch--an alternative to freeze-drying

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7 January 2021

Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

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7 January 2021

Lyophilization-induced reversible changes in the secondary structure of proteins

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7 January 2021

Irreversible inactivation of interleukin 2 in a pump-based delivery environment

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7 January 2021

Protective effect of sucrose on spray drying of oxyhemoglobin

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7 January 2021

The effect of process and formulation variables on the properties of spray-dried beta-galactosidase

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7 January 2021

On the role of surface tension in the stabilization of globular proteins

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7 January 2021

Contribution of the surface free energy perturbation to protein-solvent interactions

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7 January 2021

Stabilization of protein structure by sugars

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7 January 2021

An infrared spectroscopic study of the interactions of carbohydrates with dried proteins

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7 January 2021

Comparison of various molecular forms of bovine trypsin: correlation of infrared spectra with X-ray crystal structures

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7 January 2021

Thermally induced denaturation of lyophilized bovine somatotropin and lysozyme as impacted by moisture and excipients

1 reference

7 January 2021

Hydration and thermal denaturation of β-lactoglobulin. A calorimetric study

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7 January 2021

Effects of bovine somatotropin (rbSt) concentration at different moisture levels on the physical stability of sucrose in freeze-dried rbSt/sucrose mixtures

1 reference

7 January 2021

Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders

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7 January 2021

Decreased protein-stabilizing effects of cryoprotectants due to crystallization

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7 January 2021

Solid-phase aggregation of proteins under pharmaceutically relevant conditions

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7 January 2021

Separation of freezing- and drying-induced denaturation of lyophilized proteins using stress-specific stabilization. I. Enzyme activity and calorimetric studies

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7 January 2021

Identifiers

DOI

10.1021/JS980011E

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5 October 2017

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