(Q36718146)

15 August 2017

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title

Fluoroartemisinins: metabolically more stable antimalarial artemisinin derivatives (English)

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15 August 2017

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Jean-Pierre Bégué

1

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15 August 2017

Danièle Bonnet-Delpon

series ordinal

2

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15 August 2017

publication date

1 May 2007

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15 August 2017

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15 August 2017

volume

2

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15 August 2017

issue

5

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15 August 2017

page(s)

608-624

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Recent advances in artemisinin and its derivatives as antimalarial and antitumor agents

15 August 2017

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Artemisinin and derivatives: the future for malaria treatment?

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The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden

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Averting a malaria disaster

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Medical need, scientific opportunity and the drive for antimalarial drugs

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7 January 2021

A medicinal chemistry perspective on artemisinin and related endoperoxides

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Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.

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Drug combinations for malaria: time to ACT?

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7 January 2021

Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication

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Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases

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7 January 2021

Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite

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7 January 2021

Stereoselective Preparation of 10α- and 10β-Aryl Derivatives of Dihydroartemisinin

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7 January 2021

Synthesis and antimalarial activities of 12 beta-allyldeoxoartemisinin and its derivatives

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7 January 2021

Syntheses and Antimalarial Activities of 10-Substituted Deoxoartemisinins

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7 January 2021

Fluoro artemisinins: difluoromethylene ketones

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7 January 2021

C-10 Ester and Ether Derivatives of Dihydroartemisinin − 10-α Artesunate, Preparation of Authentic 10-β Artesunate, and of Other Ester and Ether Derivatives Bearing Potential Aromatic Intercalating Groups at C-10

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7 January 2021

Orally Active, Hydrolytically Stable, Semisynthetic, Antimalarial Trioxanes in the Artemisinin Family

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7 January 2021

Direct conversion of pyranose anomeric OH→F→R in the artemisinin family of antimalarial trioxanes

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7 January 2021

First synthesis of 10 alpha-(trifluoromethyl)deoxoartemisinin

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7 January 2021

Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin

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7 January 2021

Syntheses and antimalarial activities of N-substituted 11-azaartemisinins

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7 January 2021

Convenient access both to highly antimalaria-active 10-arylaminoartemisinins, and to 10-alkyl ethers including artemether, arteether, and artelinate

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7 January 2021

Artemisone--a highly active antimalarial drug of the artemisinin class

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7 January 2021

Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX

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7 January 2021

Acid catalyzed michael additions to artemisitene

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7 January 2021

From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements

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7 January 2021

Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues

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7 January 2021

Fluorine in medicinal chemistry

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7 January 2021

Synthesis and antimalarial activities of several fluorinated artemisinin derivatives

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7 January 2021

Metabolism of antimalarial sesquiterpene lactones.

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7 January 2021

Hepatic metabolism of artemisinin drugs—I. Drug metabolism in rat liver microsomes

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7 January 2021

Hepatic metabolism of artemisinin drugs—II. Metabolism of arteether in rat liver cytosol

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7 January 2021

Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 2. Stereospecificity of the ether side chain

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7 January 2021

Antimalarial activity of new water-soluble dihydroartemisinin derivatives

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7 January 2021

Antimalarial activity of new dihydroartemisinin derivatives. 5. Sugar analogues

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7 January 2021

Antimalarial activity of new dihydroartemisinin derivatives. 6. alpha-Alkylbenzylic ethers

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7 January 2021

Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin

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7 January 2021

Anhydrodihydroartemisinin and its 10-trifluoromethyl analogue: access to novel d-ring-contracted artemisinin trifluoromethyl ketones

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7 January 2021

Steric effects. A study of a rationally designed system

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7 January 2021

Preparation of 10-trifluoromethyl artemether and artesunate. Influence of hexafluoropropan-2-ol on substitution reaction

1 reference

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7 January 2021

Cobalt-Induced C-N and C-C Bond Formation via Metal-Stabilized alpha-CF(3) Carbenium Ion

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7 January 2021

Highly enantioselective catalytic Michael reaction of α-substituted malonates using La-linked-BINOL complex in the presence of HFIP (1,1,1,3,3,3-hexafluoroisopropanol)

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7 January 2021

Oxidation Reactions Using Urea-Hydrogen Peroxide; A Safe Alternative to Anhydrous Hydrogen Peroxide

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7 January 2021

Facile ring opening of oxiranes with aromatic amines in fluoro alcohols

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7 January 2021

C10-modified artemisinin derivatives: efficient heme-alkylating agents

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7 January 2021

Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.

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7 January 2021

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin

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7 January 2021

The effect of 10 alpha-trifluoromethylhydroartemisinin on Plasmodium berghei infection and its toxicity in experimental animals

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7 January 2021

Synthesis and antimalarial activity of (+)-deoxoartemisinin

1 reference

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7 January 2021

A new method for the deoxygenation of secondary alcohols

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Fluorinated Ylides and Related Compounds

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Reactions of difluoroenoxysilanes with glycosyl donors: synthesis of difluoro-C-glycosides and difluoro-C-disaccharides.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 3. Aromatic amine analogues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Antimalarial activity of novel ring-contracted artemisinin derivatives

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

C-16 artemisinin derivatives and their antimalarial and cytotoxic activities: syntheses of artemisinin monomers, dimers, trimers, and tetramers by nucleophilic additions to artemisitene.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Brominations with N-bromosuccinimide and related compounds; the Wohl-Ziegler reaction

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Azides: their preparation and synthetic uses

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

S(N)/S(N)' competition: selective access to new 10-fluoro artemisinins.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200600156

7 January 2021

Identifiers

DOI

10.1002/CMDC.200600156

1 reference

release_za77drd4czfb5m4tpkby7in5iu

15 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/za77drd4czfb5m4tpkby7in5iu

24 November 2022

mapped directly with Wikidata item

1 reference