(Q36737714)

English

The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension

scientific article published on 2 January 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

based on heuristic

inferred from title

calorie restriction

1 reference

based on heuristic

inferred from title

author name string

Erin Easlon

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Felicia Tsang

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Ivanka Dilova

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Chen Wang

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Shu-Ping Lu

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Craig Skinner

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Su-Ju Lin

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

2 January 2007

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

282

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

6161-6171

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

YIL042c and YOR090c encode the kinase and phosphatase of the Saccharomyces cerevisiae pyruvate dehydrogenase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Regulation of the pyruvate dehydrogenase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

1 reference

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29 September 2017

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

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29 September 2017

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

1 reference

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29 September 2017

HST2 mediates SIR2-independent life-span extension by calorie restriction

1 reference

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29 September 2017

How mitochondria fuse

1 reference

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29 September 2017

Metabolic stress regulates basic transcription through acetyl-coenzyme A.

1 reference

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29 September 2017

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

1 reference

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29 September 2017

TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.

1 reference

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29 September 2017

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Calorie restriction extends yeast life span by lowering the level of NADH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Auto-acetylation of transcription factors as a control mechanism in gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

On respiratory impairment in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

The chronological life span of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Asymmetric inheritance of oxidatively damaged proteins during cytokinesis

1 reference

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29 September 2017

Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Separation of mother and daughter cells

1 reference

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29 September 2017

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites

1 reference

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29 September 2017

Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Caloric restriction in primates and relevance to humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Regulation of longevity and stress resistance by Sch9 in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

1 reference

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29 September 2017

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

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29 September 2017

Sir2 links chromatin silencing, metabolism, and aging

1 reference

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29 September 2017

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

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Acetyl coenzyme A stimulates RNA polymerase II transcription and promoter binding by transcription factor IID in the absence of histones

1 reference

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29 September 2017

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

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29 September 2017

Elimination of replication block protein Fob1 extends the life span of yeast mother cells.

1 reference

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Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae

1 reference

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29 September 2017

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

1 reference

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29 September 2017

A new efficient gene disruption cassette for repeated use in budding yeast

1 reference

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29 September 2017

Oxidative stress, caloric restriction, and aging

1 reference

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29 September 2017

Expression, purification, and characterization of the dihydrolipoamide dehydrogenase-binding protein of the pyruvate dehydrogenase complex from Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440684

29 September 2017

The pyruvate dehydrogenase complex of Saccharomyces cerevisiae is regulated by phosphorylation

1 reference

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29 September 2017

Disruption and mutagenesis of the Saccharomyces cerevisiae PDX1 gene encoding the protein X component of the pyruvate dehydrogenase complex

1 reference

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29 September 2017

Functional analysis of the domains of dihydrolipoamide acetyltransferase from Saccharomyces cerevisiae

1 reference

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29 September 2017

Regulation of the yeast CYT1 gene encoding cytochrome c1 by HAP1 and HAP2/3/4

1 reference

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29 September 2017

Pyruvate metabolism in Saccharomyces cerevisiae

1 reference

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29 September 2017

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

1 reference

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Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

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21 January 2018

Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by (13)C NMR spectroscopy with multiple (13)C labels

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21 January 2018

Enhanced gluconeogenesis and increased energy storage as hallmarks of aging in Saccharomyces cerevisiae

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21 January 2018

Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria

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21 January 2018

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications

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21 January 2018

Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease

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21 January 2018

Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae: common targets and prevention by calorie restriction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607661200

21 January 2018

Phosphorylation-dephosphorylation of pyruvate dehydrogenase from bakers' yeast

1 reference

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21 January 2018

Role of dihydrolipoyl dehydrogenase (E3) and a novel E3-binding protein in the NADH sensitivity of the pyruvate dehydrogenase complex from anaerobic mitochondria of the parasitic nematode, Ascaris suum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607661200

21 January 2018

Stoichiometry and compartmentation of NADH metabolism inSaccharomyces cerevisiae

1 reference

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21 January 2018

Mitochondria-targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis in Saccharomyces cerevisiae.

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5 September 2018

Purification of Saccharomcyes cerevisiae Mitochondria Devoid of Microsomal and Cytosolic Contaminations

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21 January 2018

Increase in activity during calorie restriction requires Sirt1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17200108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/17200108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An intervention resembling caloric restriction prolongs life span and retards aging in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17200108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energy deregulation: licensing tumors to grow

1 reference

https://pubmed.ncbi.nlm.nih.gov/17200108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17200108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate dehydrogenase complex from baker's yeast. 1. Purification and some kinetic and regulatory properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/17200108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M607661200

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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