(Q36742102)

English

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites

scientific article published on 15 February 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

7

object named as

Richard O C Oreffo

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Mary B Goldring

9

object named as

Mary B Goldring

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Ko Hashimoto

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Miguel Otero

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Kei Imagawa

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

María C de Andrés

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Jonathan M Coico

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Helmtrud I Roach

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Kenneth B Marcu

8

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

15 February 2013

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 August 2017

288

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

10061-10072

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Cancer epigenetics: from mechanism to therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs.

1 reference

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29 September 2017

Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation.

1 reference

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29 September 2017

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.

1 reference

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Epigenetic alterations in autoimmune rheumatic diseases.

1 reference

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29 September 2017

CpG methylation of half-CRE sequences creates C/EBPalpha binding sites that activate some tissue-specific genes

1 reference

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29 September 2017

HIF-2α as a possible therapeutic target of osteoarthritis

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Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis

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29 September 2017

Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression

1 reference

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29 September 2017

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

1 reference

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29 September 2017

Epigenetic modifications in rheumatoid arthritis

1 reference

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29 September 2017

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence

1 reference

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29 September 2017

ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

Stability and flexibility of epigenetic gene regulation in mammalian development

1 reference

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29 September 2017

The complex language of chromatin regulation during transcription

1 reference

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29 September 2017

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

1 reference

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29 September 2017

Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients

1 reference

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29 September 2017

DNA methylation dictates histone H3K4 methylation

1 reference

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29 September 2017

DNA methylation profiling of human chromosomes 6, 20 and 22

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

DNA methylation in osteoarthritic chondrocytes: a new molecular target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

Osteoarthritis: pathobiology-targets and ways for therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617244

29 September 2017

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

1 reference

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29 September 2017

Hypoxia-inducible factor and its biomedical relevance

1 reference

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29 September 2017

DNA methylation has a local effect on transcription and histone acetylation

1 reference

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29 September 2017

Hypoxia--a key regulatory factor in tumour growth

1 reference

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29 September 2017

DNA methylation patterns and epigenetic memory

1 reference

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29 September 2017

IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways

1 reference

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29 September 2017

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

1 reference

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29 September 2017

HIF-1 and human disease: one highly involved factor

1 reference

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29 September 2017

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

1 reference

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Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation

1 reference

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29 September 2017

CpG methylation, chromatin structure and gene silencing-a three-way connection

1 reference

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29 September 2017

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1 reference

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29 September 2017

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

1 reference

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29 September 2017

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis

1 reference

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29 September 2017

A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

1 reference

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29 September 2017

The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis

1 reference

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29 September 2017

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

1 reference

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29 September 2017

Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop

1 reference

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29 September 2017

Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes

1 reference

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29 September 2017

NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site.

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28 June 2018

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

1 reference

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Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage

1 reference

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28 June 2018

Identification in human osteoarthritic chondrocytes of proteins binding to the novel regulatory site AGRE in the human matrix metalloprotease 13 proximal promoter

1 reference

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28 June 2018

Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

1 reference

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28 June 2018

Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

1 reference

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28 June 2018

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

1 reference

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5 September 2018

Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts.

1 reference

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5 September 2018

Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage.

1 reference

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5 September 2018

Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter.

1 reference

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5 September 2018

Improved quantification of DNA methylation using methylation-sensitive restriction enzymes and real-time PCR.

1 reference

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5 September 2018

Specific targeting of cytosine methylation to DNA sequences in vivo

1 reference

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5 September 2018

DNA methylation is not likely to be responsible for aggrecan down regulation in aged or osteoarthritic cartilage

1 reference

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5 September 2018

Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes

1 reference

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5 September 2018

Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression

1 reference

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5 September 2018

The multiple contributions of thyroid hormone to heat production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.421156

21 January 2018

Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation is not responsible for p21WAF1/CIP1 down-regulation in osteoarthritic chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/23417678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.421156

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

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