(Q36743706)

16 August 2017

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title

Imaging of cholinergic and monoaminergic neurochemical changes in neurodegenerative disorders (English)

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16 August 2017

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1

Nicolaas I Bohnen

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16 August 2017

Kirk A Frey

2

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16 August 2017

language of work or name

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1 July 2007

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Molecular Imaging and Biology

16 August 2017

published in

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16 August 2017

volume

9

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16 August 2017

issue

4

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16 August 2017

page(s)

243-257

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Opening a window on cerebral cholinergic function: PET imaging of acetylcholinesterase

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

The distribution of cerebral muscarinic acetylcholine receptors in vivo in patients with dementia. A controlled study with 123IQNB and single photon emission computed tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

Effect of donepezil on brain acetylcholinesterase activity in patients with AD measured by PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

Striatal dopamine transporter in dementia with Lewy bodies and Parkinson disease: a comparison.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

PET imaging of the dopamine transporter in progressive supranuclear palsy and Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

Fortnightly Review: Parkinsonism--recognition and differential diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

PROGRESSIVE SUPRANUCLEAR PALSY. A HETEROGENEOUS DEGENERATION INVOLVING THE BRAIN STEM, BASAL GANGLIA AND CEREBELLUM WITH VERTICAL GAZE AND PSEUDOBULBAR PALSY, NUCHAL DYSTONIA AND DEMENTIA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

Cholinergic vesicular transporters in progressive supranuclear palsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11307-007-0083-6

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease

21 January 2018

1 reference

12 December 2020

Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover

1 reference

12 December 2020

Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways

1 reference

12 December 2020

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

1 reference

12 December 2020

Imaging of nicotinic and muscarinic receptors in Alzheimer's disease: effect of tacrine treatment.

1 reference

12 December 2020

Neurological cholinesterases in the normal brain and in Alzheimer's disease: relationship to plaques, tangles, and patterns of selective vulnerability.

1 reference

12 December 2020

Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles

1 reference

12 December 2020

Brain acetylcholinesterase after acute parathion poisoning: a comparative quantitative histochemical analysis post mortem.

1 reference

12 December 2020

Evidence that tobacco smoking increases the density of (-)-[3H]nicotine binding sites in human brain

1 reference

12 December 2020

Cholinergic innervation of the human cerebellum

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12 December 2020

Selective loss of central cholinergic neurons in Alzheimer's disease

1 reference

12 December 2020

Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease

1 reference

12 December 2020

Synthesis of an I-123 analog of A-85380 and preliminary SPECT imaging of nicotinic receptors in baboon

1 reference

12 December 2020

The vesicular monoamine transporter is not regulated by dopaminergic drug treatments

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12 December 2020

Overlap between acetylcholinesterase-rich and choline acetyltransferase-positive (cholinergic) axons in human cerebral cortex

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12 December 2020

Cholinergic-dependent cognitive deficits in Parkinson's disease.

1 reference

12 December 2020

The alpha 5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

1 reference

12 December 2020

External imaging of cerebral muscarinic acetylcholine receptors

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12 December 2020

[3H]Dihydrotetrabenazine, a new marker for the visualization of dopaminergic denervation in the rat striatum.

1 reference

12 December 2020

Molecular biology of serotonin (5-HT) receptors

1 reference

12 December 2020

Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease

1 reference

12 December 2020

Reduced striatal vesicular monoamine transporters after neurotoxic but not after behaviorally-sensitizing doses of methamphetamine

1 reference

12 December 2020

The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens

1 reference

12 December 2020

Brain imaging of 18F-fallypride in normal volunteers: blood analysis, distribution, test-retest studies, and preliminary assessment of sensitivity to aging effects on dopamine D-2/D-3 receptors

1 reference

12 December 2020

Neuronal nicotinic receptors in the human brain

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12 December 2020

Anatomy of cholinesterase inhibition in Alzheimer's disease: effect of physostigmine and tetrahydroaminoacridine on plaques and tangles

1 reference

12 December 2020

Decreased striatal monoaminergic terminals in multiple system atrophy detected with positron emission tomography

1 reference

12 December 2020

Decreased uptake and binding of 11C-nicotine in brain of Alzheimer patients as visualized by positron emission tomography

1 reference

12 December 2020

Imaging brain cholinergic activity with positron emission tomography: its role in the evaluation of cholinergic treatments in Alzheimer's dementia

1 reference

12 December 2020

Striatal D2 receptor status in patients with Parkinson's disease, striatonigral degeneration, and progressive supranuclear palsy, measured with 11C-raclopride and positron emission tomography

1 reference

12 December 2020

Regional distribution of muscarinic cholinergic receptors in rat brain

1 reference

12 December 2020

Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380.

1 reference

12 December 2020

Basal forebrain neurons in the dementia of Parkinson disease

1 reference

12 December 2020

Positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in Parkinson's disease and progressive supranuclear palsy

1 reference

12 December 2020

Striatal dopamine distribution in parkinsonian patients during life

1 reference

12 December 2020

PET evaluation of [(18)F]FCWAY, an analog of the 5-HT(1A) receptor antagonist, WAY-100635.

1 reference

12 December 2020

Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study

1 reference

12 December 2020

Dopa decarboxylase activity of the living human brain

1 reference

12 December 2020

Brain muscarinic receptors in progressive supranuclear palsy and Parkinson's disease: a positron emission tomographic study

1 reference

12 December 2020

1 reference

12 December 2020

Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.

1 reference

12 December 2020

Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus

1 reference

12 December 2020

Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy.

1 reference

12 December 2020

Neurotransmitter transporters in the central nervous system

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12 December 2020

Mapping nicotinic acetylcholine receptors with PET.

1 reference

12 December 2020

Pathological changes in the nucleus of Meynert in Alzheimer's and Parkinson's diseases.

1 reference

12 December 2020

Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications

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12 December 2020

In vivo studies of acetylcholinesterase activity using a labeled substrate, N-[11C]methylpiperdin-4-yl propionate ([11C]PMP).

1 reference

12 December 2020

Cholinergic receptors in human brain: effects of aging and Alzheimer disease

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12 December 2020

Structure and function of G protein-coupled receptors

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12 December 2020

Systematic regional variations in the loss of cortical cholinergic fibers in Alzheimer's disease.

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12 December 2020

Nicotinic modulation of [3H]dopamine release from striatal synaptosomes: pharmacological characterisation

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12 December 2020

Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system

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12 December 2020

Quantitative in vivo receptor binding. I. Theory and application to the muscarinic cholinergic receptor

1 reference

12 December 2020

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment

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12 December 2020

Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

1 reference

12 December 2020

Regional distribution of muscarinic acetylcholine receptor in normal and Alzheimer's-type dementia brains

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12 December 2020

Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area

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12 December 2020

2-[18F]F-A-85380: a PET radioligand for alpha4beta2 nicotinic acetylcholine receptors

1 reference

12 December 2020

Brain acetylcholinesterase activity: validation of a PET tracer in a rat model of Alzheimer's disease.

1 reference

12 December 2020

Imaging endogenous dopamine competition with [11C]raclopride in the human brain

1 reference

12 December 2020

Decreased striatal monoaminergic terminals in olivopontocerebellar atrophy and multiple system atrophy demonstrated with positron emission tomography

1 reference

12 December 2020

[18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses

1 reference

12 December 2020

Kinetic analysis of central [11C]raclopride binding to D2-dopamine receptors studied by PET--a comparison to the equilibrium analysis

1 reference

12 December 2020

Treatment effects on nigrostriatal projection integrity in partial 6-OHDA lesions: comparison of L-DOPA and pramipexole

1 reference

12 December 2020

A new PET ligand for the dopamine transporter: studies in the human brain

1 reference

12 December 2020

Reproducibility of the distribution of carbon-11-SCH 23390, a dopamine D1 receptor tracer, in normal subjects.

1 reference

12 December 2020

In vivo mapping of cholinergic terminals in normal aging, Alzheimer's disease, and Parkinson's disease.

1 reference

12 December 2020

Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease

1 reference

12 December 2020

Brain Serotonin1A Receptor Binding Measured by Positron Emission Tomography With [11C]WAY-100635

1 reference

12 December 2020

Alzheimer disease and the dementia of Parkinson disease: comparative investigations.

1 reference

12 December 2020

Differential diagnosis of Parkinson's disease, multiple system atrophy, and Steele-Richardson-Olszewski syndrome: discriminant analysis of striatal 18F-dopa PET data

1 reference

12 December 2020

Radiolabeled cholinesterase substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity

1 reference

12 December 2020

Change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats: search for an imaging index suitable for the early detection of Alzheimer's disease

1 reference

12 December 2020

Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies

1 reference

12 December 2020

Cholinergic innervation of the human thalamus: Dual origin and differential nuclear distribution

1 reference

12 December 2020

Measurement of striatal and extrastriatal dopamine D1 receptor binding potential with [11C]NNC 112 in humans: validation and reproducibility.

1 reference

12 December 2020

Uptake and regional distribution of (+)-(R)- and (-)-(S)-N-[methyl-11C]-nicotine in the brains of rhesus monkey. An attempt to study nicotinic receptors in vivo

1 reference

12 December 2020

Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain

1 reference

12 December 2020

Synthesis and characterization of binding of 5-[76Br]bromo-3-[[2(S)-azetidinyl]methoxy]pyridine, a novel nicotinic acetylcholine receptor ligand, in rat brain

1 reference

12 December 2020

Stages in the development of Parkinson's disease-related pathology

1 reference

12 December 2020

11C-DTBZ and 18F-FDG PET measures in differentiating dementias.

1 reference

12 December 2020

Short-term treatments with haloperidol or bromocriptine do not alter the density of the monoamine vesicular transporter in the substantia nigra

1 reference

12 December 2020

Effects of the nicotinic acetylcholine receptor agonist SIB-1508Y on object retrieval performance in MPTP-treated monkeys: comparison with levodopa treatment

1 reference

12 December 2020

Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease.

1 reference

12 December 2020

Ligands for in vivo imaging of nicotinic receptor subtypes in Alzheimer brain.

1 reference

12 December 2020

The distribution of oligodendroglial inclusions in multiple system atrophy and its relevance to clinical symptomatology

1 reference

12 December 2020

Human nicotinic receptors--their role in aging and dementia

1 reference

12 December 2020

Neurochemical characteristics of early and late onset types of Alzheimer's disease

1 reference

12 December 2020

Nicotinic and muscarinic subtypes in the human brain: changes with aging and dementia

1 reference

12 December 2020

Electron microscopy of cholinergic terminals and acetylcholinesterase-containing neurones in the hippocampal formation of the rat.

1 reference

12 December 2020

Mapping cocaine binding sites in human and baboon brain in vivo.

1 reference

12 December 2020

Dopamine visualized in the basal ganglia of living man.

1 reference

12 December 2020

Assessment of muscarinic receptor concentrations in aging and Alzheimer disease with [11C]NMPB and PET.

1 reference

12 December 2020

Muscarinic cholinergic receptor measurements with [18F]FP-TZTP: control and competition studies

1 reference

12 December 2020

Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease

1 reference

12 December 2020

In vivo butyrylcholinesterase activity is not increased in Alzheimer's disease synapses

1 reference

12 December 2020

Validation of a less-invasive method for measurement of serotonin synthesis rate with alpha-[11C]methyl-tryptophan

1 reference

12 December 2020

Positron emission tomography studies on the dopaminergic system and striatal opioid binding in the olivopontocerebellar atrophy variant of multiple system atrophy

1 reference

12 December 2020

1 reference

12 December 2020

High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques.

1 reference

12 December 2020

Cholinergic markers in elderly patients with early signs of Alzheimer disease

1 reference

12 December 2020

Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review

1 reference

12 December 2020

In vivo mapping of cholinergic neurons in the human brain using SPECT and IBVM.

1 reference

12 December 2020

Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease.

1 reference

12 December 2020

Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates

1 reference

12 December 2020

Nicotinic alpha4beta2 receptor imaging agents: part II. Synthesis and biological evaluation of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine (18F-nifene) in rodents and imaging by PET in nonhuman primate.

1 reference

12 December 2020

Molecular biology of dopamine receptors

1 reference

12 December 2020

Reductions in [3H]nicotinic acetylcholine binding in Alzheimer's disease and Parkinson's disease: An autobiographic study

1 reference

12 December 2020

Increased cognitive sensitivity to scopolamine with age and a perspective on the scopolamine model

1 reference

12 December 2020

In vivo imaging of human cerebral acetylcholinesterase.

1 reference

12 December 2020

[3H]methoxytetrabenazine: a high specific activity ligand for estimating monoaminergic neuronal integrity

1 reference

12 December 2020

Acetylcholinesterase-rich pyramidal neurons in Alzheimer's disease

1 reference

12 December 2020

The organization and some projections of cholinergic neurons of the mammalian forebrain.

1 reference

12 December 2020

Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine

1 reference

12 December 2020

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Norepinephrine and Epinephrine Systems

1 reference

12 December 2020

Comparative alterations of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases

1 reference

12 December 2020

Muscarinic binding and choline acetyltransferase activity in Parkinsonian subjects with reference to dementia.

1 reference

12 December 2020

Cholinergic innervation in the human hippocampal formation including the entorhinal cortex

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12 December 2020

Kinetic analysis of the 5-HT2A ligand [11C]MDL 100,907

1 reference

12 December 2020

Acetylcholinesterase-rich neurons of the human cerebral cortex: cytoarchitectonic and ontogenetic patterns of distribution

1 reference

12 December 2020

Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy

1 reference

12 December 2020

[123I]beta-CIT SPECT in multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration.

1 reference

12 December 2020

Cerebral muscarinic acetylcholinergic receptor measurement in Alzheimer's disease patients on 11C-N-methyl-4-piperidyl benzilate--comparison with cerebral blood flow and cerebral glucose metabolism

1 reference

12 December 2020

Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging

1 reference

12 December 2020

Muscarinic cholinergic receptor binding: in vivo depiction using single photon emission computed tomography and radioiodinated quinuclidinyl benzilate.

1 reference

12 December 2020

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

1 reference

12 December 2020

Design and evaluation of radioactive acetylcholine analogs for mapping brain acetylcholinesterase (AchE) in vivo

1 reference

12 December 2020

In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease

1 reference

12 December 2020

The suitability of [11C]-alpha-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C] and [14C] labeled tracer

1 reference

12 December 2020

Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex.

1 reference

12 December 2020

Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease, and vascular dementia: in vitro binding study using 5-[(125)i]-a-85380.

1 reference

12 December 2020

Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases

1 reference

12 December 2020

Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB.

1 reference

12 December 2020

Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains.

1 reference

12 December 2020

Kinetic analysis of regional (S)(-)11C-nicotine binding in normal and Alzheimer brains--in vivo assessment using positron emission tomography.

1 reference

12 December 2020

Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands.

1 reference

12 December 2020

Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.

1 reference

12 December 2020

Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease.

1 reference

12 December 2020

Kinetic modeling of [11C]raclopride: combined PET-microdialysis studies

1 reference

12 December 2020

Choline acetytransferase activity and striatal dopamine receptors in Parkinson's disease in relation to cognitive impairment

1 reference

12 December 2020

Muscarinic receptor subtypes in neuronal and non-neuronal cholinergic function

1 reference

12 December 2020

Comparison of [(18)F]altanserin and [(18)F]deuteroaltanserin for PET imaging of serotonin(2A) receptors in baboon brain: pharmacological studies

1 reference

12 December 2020

Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652

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12 December 2020

Distribution of muscarinic receptor subtypes within architectonic subregions of the primate cerebral cortex

1 reference

12 December 2020

Human cerebral acetylcholinesterase activity measured with positron emission tomography: procedure, normal values and effect of age.

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12 December 2020

Functional identification and molecular cloning of a human brain vesicle monoamine transporter

1 reference

12 December 2020

Cognitive correlates of cortical cholinergic denervation in Parkinson's disease and parkinsonian dementia.

1 reference

12 December 2020

Reduced posterior cingulate binding of I-123 iodo-dexetimide to muscarinic receptors in mild Alzheimer's disease

1 reference

12 December 2020

In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors

1 reference

12 December 2020

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

1 reference

12 December 2020

Corticobasal degeneration. A unique pattern of regional cortical oxygen hypometabolism and striatal fluorodopa uptake demonstrated by positron emission tomography

1 reference

12 December 2020

Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease

1 reference

12 December 2020

PET imaging of cortical 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease

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12 December 2020

A systematic review of prevalence and incidence studies of dementia with Lewy bodies

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12 December 2020

Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease.

1 reference

12 December 2020

10.1007/S11307-007-0083-6

Identifiers

DOI

1 reference

16 August 2017

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