(Q36744537)

English

Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman

scientific article published on 14 December 2015

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman (English)

1 reference

Europe PubMed Central

16 August 2017

phosphorylation

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Ole M. Sejersted

13

object named as

Ole Mathias Sejersted

1 reference

Europe PubMed Central

16 August 2017

11

object named as

Ivar Sjaastad

1 reference

Europe PubMed Central

16 August 2017

Jan Magnus Aronsen

4

object named as

Jan Magnus Aronsen

1 reference

Europe PubMed Central

16 August 2017

Per Kristian Lunde

6

object named as

Per Kristian Lunde

1 reference

Europe PubMed Central

16 August 2017

Pimthanya Wanichawan

3

object named as

Pimthanya Wanichawan

1 reference

Europe PubMed Central

16 August 2017

Tandekile Lubelwana Hafver

1

object named as

Tandekile Lubelwana Hafver

1 reference

Europe PubMed Central

16 August 2017

2

object named as

Kjetil Hodne

1 reference

Europe PubMed Central

16 August 2017

5

object named as

Bjørn Dalhus

1 reference

Europe PubMed Central

16 August 2017

7

object named as

Marianne Lunde

1 reference

Europe PubMed Central

16 August 2017

William Edward Louch

12

object named as

William Edward Louch

1 reference

Europe PubMed Central

16 August 2017

Cathrine Rein Carlson

14

object named as

Cathrine Rein Carlson

1 reference

Europe PubMed Central

16 August 2017

author name string

Marita Martinsen

8

1 reference

Europe PubMed Central

16 August 2017

Ulla Helene Enger

9

1 reference

Europe PubMed Central

16 August 2017

William Fuller

10

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Europe PubMed Central

16 August 2017

language of work or name

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publication date

14 December 2015

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Europe PubMed Central

16 August 2017

number of pages

19

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Journal of Biological Chemistry

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Europe PubMed Central

16 August 2017

291

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Europe PubMed Central

16 August 2017

9

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Europe PubMed Central

16 August 2017

4561-4579

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Europe PubMed Central

16 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4813481/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Sodium-calcium exchangers (NCX): molecular hallmarks underlying the tissue-specific and systemic functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Interactor-guided dephosphorylation by protein phosphatase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

The topology of the cardiac Na⁺/Ca²⁺ exchanger, NCX1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Regulation of protein phosphatase 1 by intrinsically disordered proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Ca2+ regulation of ion transport in the Na+/Ca2+ exchanger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

The PP1 binding code: a molecular-lego strategy that governs specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Structural basis for protein phosphatase 1 regulation and specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

CaMKIIδB mediates aberrant NCX1 expression and the imbalance of NCX1/SERCA in transverse aortic constriction-induced failing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Calpain-1 cleaves Rad21 to promote sister chromatid separation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Residues 248-252 and 300-304 of the cardiac Na+/Ca2+ exchanger are involved in its regulation by phospholemman.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Role of phospholemman phosphorylation sites in mediating kinase-dependent regulation of the Na+-K+-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Hidden Markov model speed heuristic and iterative HMM search procedure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

The extended PP1 toolkit: designed to create specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Roles of two Ca2+-binding domains in regulation of the cardiac Na+-Ca2+ exchanger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Phospholemman regulates cardiac Na+/Ca2+ exchanger by interacting with the exchanger's proximal linker domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Structural basis for regulation of protein phosphatase 1 by inhibitor-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Phosphorylation and other conundrums of Na/Ca exchanger, NCX1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Phospholemman phosphorylation alters its fluorescence resonance energy transfer with the Na/K-ATPase pump

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Phospholemman overexpression inhibits Na+-K+-ATPase in adult rat cardiac myocytes: relevance to decreased Na+ pump activity in postinfarction myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Identification of an endogenous inhibitor of the cardiac Na+/Ca2+ exchanger, phospholemman

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Structural basis of protein phosphatase 1 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Sodium/Calcium Exchanger (NCX1) Macromolecular Complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Type 1 phosphatase, a negative regulator of cardiac function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Cardiac excitation-contraction coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Sodium-calcium exchange: a molecular perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Sodium/calcium exchange: its physiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Initial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchanger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

29 September 2017

Molecular determinants of nuclear protein phosphatase-1 regulation by NIPP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

28 June 2018

Phospholemman-dependent regulation of the cardiac Na/K-ATPase activity is modulated by inhibitor-1 sensitive type-1 phosphatase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Serine/threonine protein phosphatase assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Intermolecular cross-linking of Na+-Ca2+ exchanger proteins: evidence for dimer formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Serine 68 of phospholemman is critical in modulation of contractility, [Ca2+]i transients, and Na+/Ca2+ exchange in adult rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Interactor-mediated nuclear translocation and retention of protein phosphatase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Phospholemman modulates Na+/Ca2+ exchange in adult rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Alterations of calcium-regulatory proteins in heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Tissue-specific expression of Na(+)-Ca2+ exchanger isoforms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4813481

5 September 2018

Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/26668322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/26668322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinatorial control of protein phosphatase-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/26668322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26668322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/26668322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ regulation in the Na+/Ca2+ exchanger involves two markedly different Ca2+ sensors

1 reference

https://pubmed.ncbi.nlm.nih.gov/26668322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M115.677898

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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