(Q36748493)

16 August 2017

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title

Multiple biomarkers in molecular oncology. I. Molecular diagnostics applications in cervical cancer detection (English)

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16 August 2017

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cervix uterine cancer

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Douglas P Malinowski

1

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16 August 2017

publication date

1 March 2007

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

16 August 2017

published in

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16 August 2017

volume

7

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16 August 2017

issue

2

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16 August 2017

page(s)

117-131

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Lessons from hereditary colorectal cancer

16 August 2017

cites work

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

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21 January 2018

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Role of KIT and platelet-derived growth factor receptors as oncoproteins

21 January 2018

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Targeted therapy in breast cancer: the HER-2/neu gene and protein

21 January 2018

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Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Delineation of prognostic biomarkers in prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Natural history of cervical squamous intraepithelial lesions: a meta-analysis

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Virologic versus cytologic triage of women with equivocal Pap smears: a meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

American Cancer Society guideline for the early detection of cervical neoplasia and cancer

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

2001 consensus guidelines for the management of women with cervical intraepithelial neoplasia

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

2001 Consensus Guidelines for the management of women with cervical cytological abnormalities

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Papillomaviruses and cancer: from basic studies to clinical application

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Mechanisms of human papillomavirus-induced oncogenesis.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Pathogenesis of human papillomaviruses in differentiating epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Cell cycle aberrations in the pathogenesis of squamous cell carcinoma of the uterine cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

The human papilloma virus E7 oncoprotein inhibits transforming growth factor-beta signaling by blocking binding of the Smad complex to its target sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Abnormal expression pattern of cyclin E in tumour cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Overexpression of cyclins A and B as markers of neoplastic glandular lesions of the cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Evaluation of p16INK4a and pRb expression in cervical squamous and glandular neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

P16 as a molecular biomarker of cervical adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Cervical epithelial cells transduced with the papillomavirus E6/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Human papillomavirus type 16 E6 activates TERT gene transcription through induction of c-Myc and release of USF-mediated repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Ki-67 immunocytochemistry in liquid based cervical cytology: useful as an adjunctive tool?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Significance of MiB-1 staining in smears with atypical glandular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

MIB-1 and PCNA immunostaining as a diagnostic adjunct to cervical Pap smear.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

P16INK4a as an adjunct marker in liquid-based cervical cytology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Correlation of p16INK4A Overexpression with Human Papillomavirus Infection in Cervical Adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Cellular changes induced by low-risk human papillomavirus type 11 in keratinocytes that stably maintain viral episomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Transcriptional profiling of a human papillomavirus 33-positive squamous epithelial cell line which acquired a selective growth advantage after viral integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Insulin-like growth factor-binding protein 3 expression increases during immortalization of cervical keratinocytes by human papillomavirus type 16 E6 and E7 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Identification of a proliferation gene cluster associated with HPV E6/E7 expression level and viral DNA load in invasive cervical carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Gene expression profiling of dysplastic differentiation in cervical epithelial cells harboring human papillomavirus 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

cDNA array analysis of cytobrush-collected normal and malignant cervical epithelial cells: a feasibility study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Global effects of human papillomavirus type 18 E6/E7 in an organotypic keratinocyte culture system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

The human papillomavirus type 16 E5 protein modulates ERK1/2 and p38 MAP kinase activation by an EGFR-independent process in stressed human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Activation of the canonical Wnt pathway during genital keratinocyte transformation: a model for cervical cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

The expression and tyrosine phosphorylation of E-cadherin/catenin adhesion complex, and focal adhesion kinase in invasive cervical carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

E-Cadherin and beta-Catenin expression in early stage cervical carcinoma: a tissue microarray study of 147 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

E-cadherin and catenins in early squamous cervical carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Improved cervical smear assessment using antibodies against proteins that regulate DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Over-expression of topoisomerase IIalpha is related to the grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Changes of cell adhesion and extracellular matrix (ECM) components in cervical intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Increased expressions of claudin-1 and claudin-7 during the progression of cervical neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Increased expression of claudins in cervical squamous intraepithelial neoplasia and invasive carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Overexpression of cathepsin F, matrix metalloproteinases 11 and 12 in cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Laminin-5 as a marker of invasiveness in cervical lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Laminin-5 gamma2 chain expression facilitates detection of invasive squamous cell carcinoma of the uterine cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Correlation between the tumoral expression of beta3-integrin and outcome in cervical cancer patients who had undergone radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Diagnostic Accuracy of Cervical Low-Grade Squamous Intraepithelial Lesions Is Improved With MIB-1 Immunostaining

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

p16(INK4a) expression correlates with degree of cervical neoplasia: a comparison with Ki-67 expression and detection of high-risk HPV types.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Differentiating high-grade cervical intraepithelial lesion from atrophy in postmenopausal women using Ki-67, cyclin E, and p16 immunohistochemical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Immunohistochemical staining with MIB1, bcl2 and p16 assists in the distinction of cervical glandular intraepithelial neoplasia from tubo-endometrial metaplasia, endometriosis and microglandular hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Low- and high-risk CIN 1 and 2 lesions: prospective predictive value of grade, HPV, and Ki-67 immuno-quantitative variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: role of markers of proliferative activity and differentiation and Rb availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Validation of a novel immunocytochemical assay for topoisomerase II-alpha and minichromosome maintenance protein 2 expression in cervical cytology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

Detection of cervical high-grade squamous intraepithelial lesions from cytologic samples using a novel immunocytochemical assay (ProEx C).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.7.2.117

21 January 2018

Identifiers

DOI

10.1586/14737159.7.2.117

1 reference

16 August 2017

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