(Q34150408)

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Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras.

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28 December 2019

Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras (English)

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28 December 2019

Elliot J. Androphy

5

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28 December 2019

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Oishee Chakrabarti

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28 December 2019

Karthikeyan Veeraraghavalu

2

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28 December 2019

Vinay Tergaonkar

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28 December 2019

Yun Liu

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28 December 2019

Margaret A Stanley

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28 December 2019

Sudhir Krishna

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28 December 2019

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1 June 2004

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28 December 2019

Journal of Virology

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28 December 2019

78

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28 December 2019

5934-5945

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28 December 2019

11

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28 December 2019

Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Notch1 can contribute to viral-induced transformation of primary human keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45

1 reference

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5 July 2018

Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins

1 reference

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5 July 2018

Human papillomavirus type 16 E6 and E7 gene variations in Indian cervical cancer

1 reference

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5 July 2018

Human papillomavirus immortalization and transformation functions

1 reference

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5 July 2018

Cell detachment triggers p38 mitogen-activated protein kinase-dependent overexpression of Fas ligand. A novel mechanism of Anoikis of intestinal epithelial cells

1 reference

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5 July 2018

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

1 reference

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5 July 2018

Morphological and biological heterogeneity of three tumorigenic cell lines derived from a single p53-/- osteoblast-like cell line, MMC2.

1 reference

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5 July 2018

Papillomaviruses and cancer: from basic studies to clinical application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Rap1 signalling: adhering to new models

1 reference

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5 July 2018

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

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5 July 2018

Transient deactivation of ERK signalling is sufficient for stable entry into G0 in primary avian fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Integrating the MAP kinase signal into the G1 phase cell cycle machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Immortalization of human cells and their malignant conversion by high risk human papillomavirus genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

The Hallmarks of Cancer

1 reference

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5 July 2018

Retention of cell adhesion and growth capability in human cervical cancer cells deprived of cell anchorage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Creation of human tumour cells with defined genetic elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Pleiotropic effects of human papillomavirus type 16 E6 oncogene expression in human epithelial cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Human ligands of the Notch receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Characterization of transformation function of cottontail rabbit papillomavirus E5 and E8 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Human papillomavirus 16 E6 variants are more prevalent in invasive cervical carcinoma than the prototype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

The ins and outs of notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesions

1 reference

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5 July 2018

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

PI3K: downstream AKTion blocks apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Papillomavirus infections--a major cause of human cancers

1 reference

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Analysis of HLA-DR expression on keratinocytes in cervical neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Alterations in Notch signaling in neoplastic lesions of the human cervix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

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Human papillomavirus (HPV) infections in the aetiology of cervical cancer

1 reference

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5 July 2018

ras oncogenes in human cancer: a review

1 reference

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5 July 2018

Properties of a non-tumorigenic human cervical keratinocyte cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=415794

5 July 2018

Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA.

1 reference

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5 July 2018

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

1 reference

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5 July 2018

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

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28 October 2018

In vitro and in vivo inhibition of human papillomavirus type 16 E6 and E7 genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.78.11.5934-5945.2004

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Europe PubMed Central

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28 December 2019

1 reference

Europe PubMed Central

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28 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15140991%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

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