(Q36750166)

English

Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer.

scientific article published on April 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

based on heuristic

inferred from title

ovarian carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

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Rong Wu

1

1 reference

Europe PubMed Central

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26 February 2020

Suzanne J Baker

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Tom C Hu

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Kyle M Norman

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Eric R Fearon

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

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publication date

1 April 2013

1 reference

Europe PubMed Central

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26 February 2020

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

182

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1391-1399

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Molecular imaging reveals a role for AKT in resistance to cisplatin for ovarian endometrioid adenocarcinoma

1 reference

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Novel mutations target distinct subgroups of medulloblastoma.

1 reference

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29 September 2017

Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma

1 reference

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29 September 2017

PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes

1 reference

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29 September 2017

Minireview: human ovarian cancer: biology, current management, and paths to personalizing therapy

1 reference

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29 September 2017

Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

1 reference

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29 September 2017

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Role of histological type on surgical outcome and survival following radical primary tumour debulking of epithelial ovarian, fallopian tube and peritoneal cancers.

1 reference

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29 September 2017

Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma.

1 reference

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29 September 2017

Integrated genomic analyses of ovarian carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

PAX 8 expression in non-neoplastic tissues, primary tumors, and metastatic tumors: a comprehensive immunohistochemical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Phosphatidylinositol 3-kinase: the oncoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Ovarian cancer update: lessons from morphology, molecules, and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Evidence for a latent precursor (p53 signature) that may precede serous endometrial intraepithelial carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

My approach to and thoughts on the typing of ovarian carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

The development of high-grade serous carcinoma from atypical proliferative (borderline) serous tumors and low-grade micropapillary serous carcinoma: a morphologic and molecular genetic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Rare cancer-specific mutations in PIK3CA show gain of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

The distal fallopian tube: a new model for pelvic serous carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

The oncogenic roles of p53 mutants in mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

29 September 2017

PIK3CA mutation spectrum in urothelial carcinoma reflects cell context-dependent signaling and phenotypic outputs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

28 June 2018

Distant metastases in ovarian cancer: association with p53 mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

28 June 2018

Low-grade ovarian serous neoplasms (low-grade serous carcinoma and serous borderline tumor) associated with high-grade serous carcinoma or undifferentiated carcinoma: report of a series of cases of an unusual phenomenon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

The genesis and evolution of high-grade serous ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

High-grade serous carcinoma arising in a low-grade serous carcinoma and micropapillary serous borderline tumour of the ovary in a 23-year-old woman

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

Alternate molecular genetic pathways in ovarian carcinomas of common histological types.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.

1 reference

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5 September 2018

Emerging roles for PAX8 in ovarian cancer and endosalpingeal development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

PIK3CA mutations in breast cancer are associated with poor outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

PIK3CA mutations in advanced ovarian carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620412

5 September 2018

Mutation and expression of the TP53 gene in early stage epithelial ovarian carcinoma

1 reference

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5 September 2018

p53 mutations and overexpression affect prognosis of ovarian endometrioid cancer but not clear cell cancer

1 reference

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5 September 2018

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

1 reference

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5 September 2018

Early recurrence of ovarian serous borderline tumor as high-grade carcinoma: a report of two cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 protein as a predictor of survival in endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA mutations in the kinase domain (exon 20) of uterine endometrial adenocarcinomas are associated with adverse prognostic parameters

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tubal origin of 'ovarian' low-grade serous carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The differential expression of PAX2 and PAX8 in the ovarian surface epithelium and fallopian tubal epithelium is an important issue

1 reference

https://pubmed.ncbi.nlm.nih.gov/23499052

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJPATH.2012.12.031

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23499052%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

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