(Q36754801)

16 August 2017

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title

Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments? (English)

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16 August 2017

3

Meindert Danhof

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16 August 2017

Daniël M Jonker

1

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16 August 2017

Rob A Voskuyl

series ordinal

2

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16 August 2017

publication date

1 March 2007

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16 August 2017

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16 August 2017

volume

48

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16 August 2017

issue

3

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16 August 2017

page(s)

412-434

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Changes in plasma protein binding have little clinical relevance

16 August 2017

cites work

1 reference

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The non-competitive AMPA/kainate receptor antagonist, GYKI 52466, potentiates the anticonvulsant activity of conventional antiepileptics.

21 January 2018

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Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice.

21 January 2018

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7-nitroindazole differentially affects the anticonvulsant activity of antiepileptic drugs against amygdala-kindled seizures in rats.

21 January 2018

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The AMPA/kainate receptor antagonist, LY 300164, increases the anticonvulsant effects of diazepam.

21 January 2018

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N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats.

21 January 2018

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Glutamate receptor antagonists differentially affect the protective activity of conventional antiepileptics against amygdala-kindled seizures in rats

21 January 2018

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Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis.

21 January 2018

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Restoration of antibacterial activity of beta-lactams by epigallocatechin gallate against beta-lactamase-producing species depending on location of beta-lactamase

21 January 2018

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Interaction of loreclezole with conventional antiepileptic drugs in amygdala-kindled rats

21 January 2018

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Antiepileptic drug combinations and experimental background: the case of phenobarbital and phenytoin

21 January 2018

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Primidone, phenobarbital, and PEMA: II. Seizure protection, neurotoxicity, and therapeutic index of varying combinations in mice

21 January 2018

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Competitive antagonists of NMDA receptors, CGP 37849 and CGP 39551, enhance the anticonvulsant activity of valproate against electroconvulsions in mice.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Polytherapy in epilepsy: the experimental evidence

21 January 2018

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LY 300164, a novel antagonist of AMPA/kainate receptors, potentiates the anticonvulsive activity of antiepileptic drugs.

21 January 2018

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GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors.

21 January 2018

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Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.

21 January 2018

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Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice

21 January 2018

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Influence of retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice

21 January 2018

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Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed

21 January 2018

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Pharmacodynamic interaction between phenytoin and sodium valproate changes seizure thresholds and pattern

21 January 2018

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Evaluation of in vivo interactions in mice between flurazepam and two neuroactive steroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Interaction of felbamate and diazepam against maximal electroshock seizures and chemoconvulsants in mice

21 January 2018

1 reference

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Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Towards a mechanism-based analysis of pharmacodynamic drug-drug interactions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

AMPA and GABA(B) receptor antagonists and their interaction in rats with a genetic form of absence epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Roles of group II metabotropic glutamate receptors in modulation of seizure activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Early identification of refractory epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Isobolographic and subthreshold methods in the detection of interactions between oxcarbazepine and conventional antiepileptics--a comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Interactions between oxcarbazepine and conventional antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Pharmacodynamic and pharmacokinetic characterization of interactions between levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: an isobolographic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Anticonvulsant effects of levetiracetam and levetiracetam-diazepam combinations in experimental status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Response surface model for anesthetic drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Phenytoin and carbamazepine, alone and in combination: anticonvulsant and neurotoxic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Involvement of a GABAergic mechanism in the anticonvulsant effect of pentobarbital against maximal electroshock-induced seizures in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Pharmacodynamic interaction studies with topiramate in the pentylenetetrazol and maximal electroshock seizure models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Models for epilepsy and epileptogenesis: report from the NIH workshop, Bethesda, Maryland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Interaction of topiramate with conventional antiepileptic drugs in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Iso-S-petasin, a hypotensive sesquiterpene from Petasites formosanus, depresses cardiac contraction and intracellular Ca2+ transients in adult rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Influence of MK-801 on the anticonvulsant activity of antiepileptics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Antiparkinsonian drugs memantine and trihexyphenidyl potentiate the anticonvulsant activity of valproate against maximal electroshock-induced seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Properties of the convulsive threshold determined by direct cortical stimulation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Effect of the glycine/NMDA receptor partial agonist, D-cycloserine, on seizure threshold and some pharmacodynamic effects of MK-801 in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline enhances the protective activity of common antiepileptic drugs against maximal electroshock-induced seizures in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

The competitive NMDA antagonist, D-CPP-ene, potentiates the anticonvulsant activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

Coadministration of gabapentin or MK-801 with lamotrigine slows tolerance to its anticonvulsant effects on kindled seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2006.00952.X

10.1111/J.1528-1167.2006.00952.X

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference