(Q36756506)

16 August 2017

Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity (English)

1 reference

16 August 2017

0 references

Chloé C Féral

1

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Jerrold M. Olefsky

5

object named as

Jerrold M Olefsky

1 reference

16 August 2017

Jaap G Neels

2

1 reference

16 August 2017

Christiane Kummer

3

1 reference

16 August 2017

Marina Slepak

4

1 reference

16 August 2017

Mark H Ginsberg

6

1 reference

16 August 2017

language of work or name

English

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publication date

21 April 2008

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16 August 2017

10

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inferred from page(s)

published in

Diabetes

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16 August 2017

57

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16 August 2017

7

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16 August 2017

1842-1851

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describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2453617/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

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Cardiovascular metabolic syndrome - an interplay of, obesity, inflammation, diabetes and coronary heart disease

29 September 2017

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Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

29 September 2017

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Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance

29 September 2017

1 reference

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Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus

29 September 2017

1 reference

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Inflammatory process in type 2 diabetes: The role of cytokines.

29 September 2017

1 reference

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Therapeutic strategies in autoimmune diseases by interfering with leukocyte endothelium interaction

29 September 2017

1 reference

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Therapeutic targeting of molecules involved in leukocyte-endothelial cell interactions

29 September 2017

1 reference

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New approaches to blockade of alpha4-integrins, proven therapeutic targets in chronic inflammation

29 September 2017

1 reference

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

29 September 2017

1 reference

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Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site

29 September 2017

1 reference

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Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain

29 September 2017

1 reference

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

29 September 2017

1 reference

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Monocyte and macrophage heterogeneity

29 September 2017

1 reference

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Inflammation and the etiology of type 2 diabetes

29 September 2017

1 reference

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Role of macrophage tissue infiltration in metabolic diseases.

29 September 2017

1 reference

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IKK-beta links inflammation to obesity-induced insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Obesity is associated with macrophage accumulation in adipose tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Natalizumab for active Crohn's disease

29 September 2017

1 reference

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Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment

29 September 2017

1 reference

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Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

29 September 2017

1 reference

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Evolution from obesity to diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

The pathophysiologic role of alpha 4 integrins in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

VLA proteins in the integrin family: structures, functions, and their role on leukocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Optimum numerical integration methods for estimation of area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Rapid recruitment of inflammatory monocytes is independent of neutrophil migration

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

A controlled trial of natalizumab for relapsing multiple sclerosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

α4Integrins as Therapeutic Targets in Autoimmune Disease

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453617

Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo

4 December 2018

1 reference

12 December 2020

Inhibition of Th1- and enhancement of Th2-initiating cytokines and chemokines in trichosanthin- treated macrophages

1 reference

12 December 2020

Differential requirements for alpha4 integrins during fetal and adult hematopoiesis

1 reference

12 December 2020

Inhibition of alpha4 integrin and ICAM-1 markedly attenuate macrophage homing to atherosclerotic plaques in ApoE-deficient mice

1 reference

12 December 2020

Tysabri raises alarm bells on drug class

1 reference

12 December 2020

Third Tysabri adverse case hits drug class

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB07-1751

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

18426864

1 reference