(Q36757025)

English

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.

scientific article published on 5 May 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25939491%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25939491%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

metastatic melanoma

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inferred from title

1

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7 March 2020

Smita S Chandran

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7 March 2020

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7 March 2020

Philip D Gregory

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7 March 2020

Nicholas P. Restifo

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7 March 2020

Steven Rosenberg

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7 March 2020

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7 March 2020

Steven R. Feldman

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Steven A Feldman

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7 March 2020

Daniel Abate-Daga

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7 March 2020

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7 March 2020

David E Paschon

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7 March 2020

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Andreas Reik

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7 March 2020

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Gary Lee

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7 March 2020

Matthew Mendel

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7 March 2020

Mini Bharathan

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7 March 2020

Mary Black

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7 March 2020

Nimisha Gandhi

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7 March 2020

Zhiya Yu

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7 March 2020

Martin Giedlin

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7 March 2020

Dale Ando

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7 March 2020

Jeff Miller

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7 March 2020

Michael C Holmes

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7 March 2020

Richard A Morgan

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7 March 2020

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5 May 2015

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7 March 2020

Molecular Therapy

1 reference

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7 March 2020

23

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7 March 2020

8

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7 March 2020

1380-1390

1 reference

Europe PubMed Central

PMC publication ID

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7 March 2020

IL-2: the first effective immunotherapy for human cancer.

1 reference

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29 September 2017

Programmed death-1 pathway in cancer and autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Targeted genome editing tools for disease modeling and gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes

1 reference

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29 September 2017

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

1 reference

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29 September 2017

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

1 reference

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29 September 2017

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

1 reference

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29 September 2017

RNA-guided human genome engineering via Cas9

1 reference

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29 September 2017

TALENs: a widely applicable technology for targeted genome editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody

1 reference

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29 September 2017

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Adoptive immunotherapy for cancer: harnessing the T cell response

1 reference

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29 September 2017

The blockade of immune checkpoints in cancer immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

A TALE nuclease architecture for efficient genome editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Genome editing with engineered zinc finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

A rapid and general assay for monitoring endogenous gene modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4817870

29 September 2017

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

1 reference

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29 September 2017

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

1 reference

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29 September 2017

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

1 reference

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29 September 2017

Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination

1 reference

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29 September 2017

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

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29 September 2017

Cancer regression in patients after transfer of genetically engineered lymphocytes

1 reference

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29 September 2017

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

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29 September 2017

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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29 September 2017

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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29 September 2017

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1 reference

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20 October 2018

Tumor-specific cytolysis by lymphocytes infiltrating human melanomas

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12 December 2020

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7 March 2020

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7 March 2020

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