(Q36759016)

16 August 2017

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title

Human embryonic stem cells and gene therapy (English)

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human embryonic stem cell

16 August 2017

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Yael Strulovici

1

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16 August 2017

Philip L Leopold

2

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16 August 2017

Timothy P O'Connor

3

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16 August 2017

Robert G Pergolizzi

4

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16 August 2017

Ronald G Crystal

5

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16 August 2017

20 March 2007

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16 August 2017

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16 August 2017

15

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16 August 2017

5

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16 August 2017

850-866

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describes a project that uses

16 August 2017

CHA-hES1

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CHA-hES2

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cites work

Derivation and spontaneous differentiation of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Characterization and Differentiation of Human Embryonic Stem Cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Characterization and culture of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

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https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Generation, culture, and differentiation of human embryonic stem cells for therapeutic applications

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stem cells and tissue engineering: past, present, and future

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation of clinical-grade human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

The derivation of clinical-grade human embryonic stem cell lines

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Embryonic stem cell lines derived from human blastocysts

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Morula-derived human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation of human embryonic stem cells from developing and arrested embryos

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Human embryonic stem cell lines derived from single blastomeres

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Human embryonic stem cells as a cellular model for human disorders

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stem cells: science, policy, and ethics

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Ethical sourcing of human embryonic stem cells--rational solutions?

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Is a consensus possible on stem cell research? Moral and political obstacles

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Genetic medicines: treatment strategies for hereditary disorders

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Embryonic stem cells from parthenotes.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

New frontiers in gene targeting and cloning: success, application and challenges in domestic animals and human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Cloning adult farm animals: a review of the possibilities and problems associated with somatic cell nuclear transfer.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Nuclear reprogramming and pluripotency

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Histocompatible embryonic stem cells by parthenogenesis

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

The clinical potential of stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Preimplantation genetic diagnosis as a novel source of embryos for stem cell research

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Human embryonic stem cell lines with genetic disorders

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Homologous recombination in human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Nucleofection of human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Enhancing and diminishing gene function in human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Maintenance of pluripotency in human embryonic stem cells stably over-expressing enhanced green fluorescent protein.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stably transfected human embryonic stem cell clones express OCT4-specific green fluorescent protein and maintain self-renewal and pluripotency

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Infection Efficiency of Human and Mouse Embryonic Stem Cells Using Adenoviral and Adeno-Associated Viral Vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Human embryonic stem cells: genetic manipulation on the way to cardiac cell therapies

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Genetic engineering of human embryonic stem cells with lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stable genetic modification of human embryonic stem cells by lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Specific and stable gene transfer to human embryonic stem cells using pseudotyped lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

The prokaryotic neomycin-resistance-encoding gene acts as a transcriptional silencer in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Protection of uninfected human bone marrow cells in long-term culture from G418 toxicity after retroviral-mediated transfer of the NEOr gene.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Effects of sequences of prokaryotic origin on titer and transgene expression in retroviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Clinical-scale selection of anti-CD3/CD28-activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Safety of retroviral gene marking with a truncated NGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Survival and engraftment of mouse embryonic stem cell-derived implants in the guinea pig brain

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Selective ablation of human embryonic stem cells expressing a "suicide" gene

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Embryonic stem cell differentiation: emergence of a new era in biology and medicine

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Immortalization of primary mouse embryo fibroblasts with SV40 virions, viral DNA, and a subgenomic DNA fragment in a quantitative assay

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Instability of endogenous MRP/proliferin transcripts in the nucleus of mouse embryo fibroblasts contrasts with their stability when produced during transient transfections

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

LMP1 of Epstein-Barr virus induces proliferation of primary mouse embryonic fibroblasts and cooperatively transforms the cells with a p16-insensitive CDK4 oncogene

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotide microarrays

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Leukemia inhibitory factor-transfected embryonic fibroblasts and vascular endothelial growth factor successfully improve the skin substitute wound healing by increasing angiogenesis and matrix production

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Synthesis of biodegradable cross-linked poly(beta-amino ester) for gene delivery and its modification, inducing enhanced transfection efficiency and stepwise degradation.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Optimization of human erythropoietin secretion from MLV-infected human primary fibroblasts used for encapsulated cell therapy.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Human immunodeficiency virus pseudotypes with expanded cellular and species tropism

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Basic calcium phosphate crystal-induced Egr-1 expression stimulates mitogenesis in human fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Osteopetrotic mouse stroma with thrombopoietin, c-kit ligand, and flk-2 ligand supports long-term mobilized CD34+ hematopoiesis in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Improvement of DNA vaccine immunogenicity by a dual antigen expression system.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stable antibody expression at therapeutic levels using the 2A peptide

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Side effects of retroviral gene transfer into hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Hematopoietic stem cell gene therapy: dead or alive?

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Gene targeting with viral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Clonal derivation and characterization of human embryonic stem cell lines

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation, characterization, and differentiation of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Promoters and control elements: designing expression cassettes for gene therapy.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Conditional control of gene expression in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Pharmacologic transgene control systems for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

HLA diversity: detection and impact on unrelated hematopoietic stem cell donor characterization and selection

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

The epigenetic magic of histone lysine methylation.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Repository of human embryonic stem cell lines and development of individual specific lines using stembrid technology

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Xenotransplantation at a crossroads: prevention versus progress

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation of a xeno-free human embryonic stem cell line

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation of human embryonic stem cells in defined conditions

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation of Embryonic Stem-Cell Lines from Human Blastocysts

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Culture and characterization of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Derivation of keratinocyte progenitor cells and skin formation from embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Embryonic stem cells generate airway epithelial tissue

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stem cell-derived Sca-1+ progenitors differentiate into smooth muscle cells, which is mediated by collagen IV-integrin alpha1/beta1/alphav and PDGF receptor pathways.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Chondrogenic differentiation on perlecan domain I, collagen II, and bone morphogenetic protein-2-based matrices.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Stem cells and their niches

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Capturing and profiling adult hair follicle stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

International trial of the Edmonton protocol for islet transplantation.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Generation of histocompatible tissues using nuclear transplantation.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Proteomic signature of human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

MPSS profiling of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

A molecular scheme for improved characterization of human embryonic stem cell lines

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

The transcriptome profile of human embryonic stem cells as defined by SAGE

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Molecular signature of human embryonic stem cells and its comparison with the mouse

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Gene expression signatures of seven individual human embryonic stem cell lines

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Comparative analysis of sequence-specific DNA recombination systems in human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Efficient gene delivery in differentiated human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Establishment of human embryonic stem cell line stably expressing Epstein-Barr virus-encoded nuclear antigen 1.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Efficient transfection of embryonic and adult stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FMT.SJ.6300125

7 January 2021

Identifiers

DOI

10.1038/MT.SJ.6300125

1 reference

16 August 2017

1 reference