(Q36759089)

16 August 2017

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title

Pro-protein convertases in intermediary metabolism: islet hormones, brain/gut hormones and integrated physiology (English)

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16 August 2017

Dominique Bataille

1

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16 August 2017

publication date

14 March 2007

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Journal of Molecular Medicine

16 August 2017

published in

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16 August 2017

volume

85

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16 August 2017

issue

7

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16 August 2017

page(s)

673-684

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Heterologous processing of rat prosomatostatin to somatostatin-14 by PC2: requirement for secretory cell but not the secretion granule

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0167-4

Effects of the novel (Pro3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological increti

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0167-4

Peptides that regulate food intake: glucagon-like peptide 1-(7-36) amide acts at lateral and medial hypothalamic sites to suppress feeding in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0167-4

Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-007-0167-4

Prosomatostatin is proteolytically processed at the amino terminal segment by subtilase SKI-1.

21 January 2018

1 reference

12 December 2020

A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans

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12 December 2020

Peripheral oxyntomodulin reduces food intake and body weight gain in rats.

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12 December 2020

Glucagon-like peptide-1 inhibits glucagon-induced glycogenolysis in perivenous hepatocytes specifically

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12 December 2020

GIP or not GIP? That is the question

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12 December 2020

Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats

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12 December 2020

Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies

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12 December 2020

Isolation, purification, and characterization of gamma-lipotropic hormone from sheep pituitary glands

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12 December 2020

Separation of insulin signaling into distinct GLUT4 translocation and activation steps

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12 December 2020

Central nervous system control of food intake

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12 December 2020

Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP.

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12 December 2020

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure

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12 December 2020

Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans.

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12 December 2020

The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?

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12 December 2020

The proprotein convertases

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12 December 2020

Oxyntomodulin suppresses appetite and reduces food intake in humans

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12 December 2020

N-terminally extended somatostatin: the primary structure of somatostatin-28

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12 December 2020

Gut hormone PYY(3-36) physiologically inhibits food intake

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12 December 2020

GIP1-39, a novel insulinotropic peptide form and aspects on its mechanism of action

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12 December 2020

Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

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12 December 2020

Comparative proteolytic processing of rat prosomatostatin by the convertases PC1, PC2, furin, PACE4 and PC5 in constitutive and regulated secretory pathways

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12 December 2020

Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas

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12 December 2020

Miniglucagon (glucagon 19-29): a novel regulator of the pancreatic islet physiology

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12 December 2020

Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients

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12 December 2020

A morphological basis for intercellular communication between alpha- and beta-cells in the endocrine pancreas

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12 December 2020

Stimulation of insulin secretion by gastric inhibitory polypeptide in man

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12 December 2020

Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets

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12 December 2020

Neurons with access to the general circulation in the central nervous system of the rat: A retrograde tracing study with fluoro-gold

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12 December 2020

Oxyntomodulin-like immunoreactivity: diurnal profile of a new potential enterogastrone

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12 December 2020

Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat.

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12 December 2020

Bimodal regulation of pancreatic exocrine function in vitro by somatostatin-28

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12 December 2020

Oxyntomodulin reduces hydromineral transport through rat small intestine

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12 December 2020

Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2.

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12 December 2020

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

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12 December 2020

Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

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12 December 2020

The glucagon-miniglucagon interplay: a new level in the metabolic regulation

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12 December 2020

International Union of Pharmacology. XXXV. The glucagon receptor family

1 reference

12 December 2020

Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans

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12 December 2020

The proinsulin C-peptide--a multirole model

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12 December 2020

The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis

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12 December 2020

Effects of Somatostatin-14 and Somatostatin-28 on Bombesin-Stimulated Release of Gastrin, Insulin, and Glucagon in the Dog*

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12 December 2020

A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans

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12 December 2020

Oxyntomodulin (glucagon-37 or bioactive enteroglucagon): a potent inhibitor of pentagastrin-stimulated acid secretion in rats

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12 December 2020

Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats

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12 December 2020

Insulin biosynthesis: evidence for a precursor

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12 December 2020

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

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12 December 2020

Precursor convertases: an evolutionary ancient, cell-specific, combinatorial mechanism yielding diverse bioactive peptides and proteins

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12 December 2020

No effect of glucagon-like peptide-1 on short-term satiety and energy intake in man

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12 December 2020

C-peptide: a redundant relative of insulin?

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12 December 2020

Processing and Intracellular Targeting of Prosomatostatin‐Derived Peptides: the Role of Mammalian Endoproteases

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12 December 2020

Immunocytochemical evidence for a paracrine interaction between GIP and GLP-1-producing cells in canine small intestine

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12 December 2020

The somatostatin-28(1-12)-NPAMAP sequence: an essential helical-promoting motif governing prosomatostatin processing at mono- and dibasic sites

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12 December 2020

RAMPs: 5 years on, where to now?

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12 December 2020

Cell Contacts in Human Islets of Langerhans

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12 December 2020

Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B

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12 December 2020

The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily

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12 December 2020

Glicentin and oxyntomodulin modulate both the phosphoinositide and cyclic adenosine monophosphate signaling pathways in gastric myocytes

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12 December 2020

Physiology: does gut hormone PYY3-36 decrease food intake in rodents?

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12 December 2020

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

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12 December 2020

Miniglucagon (glucagon 19-29), a potent and efficient inhibitor of secretagogue-induced insulin release through a Ca2+ pathway

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12 December 2020

Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.

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12 December 2020

Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice

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12 December 2020

Gastric inhibitory polypeptide: the neglected incretin revisited

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12 December 2020

Glucose-dependent insulinotropic peptide: structure of the precursor and tissue-specific expression in rat

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12 December 2020

Assessment of the role of interstitial glucagon in the acute glucose secretory responsiveness of in situ pancreatic beta-cells

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12 December 2020

The Jeremiah Metzger Lecture. From POMC to functional diversity of neural peptides: the key importance of convertases.

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12 December 2020

Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR).

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12 December 2020

Central regulators of food intake

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12 December 2020

Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.

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12 December 2020

Effect of rat glicentin on intestinal adaptation in small intestine-resected rats

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12 December 2020

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

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12 December 2020

Gut hormones and diabetes mellitus

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12 December 2020

The proprotein convertase PC2 is involved in the maturation of prosomatostatin to somatostatin-14 but not in the somatostatin deficit in Alzheimer's disease

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12 December 2020

Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

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12 December 2020

Evidence that glucagon stimulates insulin secretion through its own receptor in rats

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12 December 2020

Enzymes that process somatostatin precursors. A novel endoprotease that cleaves before the arginine-lysine doublet is involved in somatostatin-28 convertase activity of rat brain cortex

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12 December 2020

Intestinal Factors in the Control of Insulin Secretion

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12 December 2020

Ghrelin causes hyperphagia and obesity in rats.

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12 December 2020

Oxyntomodulin inhibits food intake in the rat

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12 December 2020

Ghrelin, a widespread hormone: insights into molecular and cellular regulation of its expression and mechanism of action.

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12 December 2020

Pancreatic and extrapancreatic effects of GLP-1

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12 December 2020

Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men

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12 December 2020

The biology of incretin hormones

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12 December 2020

Luminal glucagon-like peptide-1(7–36) amide-releasing factors in the isolated vascularly perfused rat colon

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12 December 2020

A role for glucagon-like peptide-1 in the central regulation of feeding

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12 December 2020

N-arginine dibasic convertase (NRD convertase): a newcomer to the family of processing endopeptidases. An overview

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12 December 2020

Role of prohormone convertases in the tissue-specific processing of proglucagon

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12 December 2020

Oxyntomodulin inhibits pancreatic secretion through the nervous system in rats

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12 December 2020

Glucagon receptors on human islet cells contribute to glucose competence of insulin release

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12 December 2020

The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas

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12 December 2020

Inhibition of gastric acid secretion by oxyntomodulin and its 19-37 fragment in the conscious rat.

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12 December 2020

Glucagon-like peptide 2.

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12 December 2020

Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase

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12 December 2020

Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans

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12 December 2020

Oxyntomodulin and glicentin are potent inhibitors of the fed motility pattern in small intestine

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12 December 2020

Glicentin inhibits gastric acid secretion in the rat

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12 December 2020

Novel signal transduction and peptide specificity of glucagon-like peptide receptor in 3T3-L1 adipocytes

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12 December 2020

A Gastric Inhibitory Polypeptide II: The Complete Amino Acid Sequence

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12 December 2020

Somatostatin-14, somatostatin-28, and prosomatostatin[1-10] are independently and efficiently processed from prosomatostatin in the constitutive secretory pathway in islet somatostatin tumor cells (1027B2)

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12 December 2020

Glucagon-like peptide 1: a potent glycogenic hormone

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12 December 2020

Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro

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12 December 2020

Modern science versus the stigma of obesity

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12 December 2020

Glucagon-like peptide 1(GLP-1) in biology and pathology

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12 December 2020

Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo

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12 December 2020

The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity

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12 December 2020

From β-lipotropin to β-endorphin and 'pro-opio-melanocortin'

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12 December 2020

PLASMA INSULIN RESPONSE TO ORAL AND INTRAVENOUS GLUCOSE ADMINISTRATION

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12 December 2020

Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor

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12 December 2020

Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence

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12 December 2020

10.1007/S00109-007-0167-4

Identifiers

DOI

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16 August 2017

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