(Q40556016)

21 September 2017

Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets (English)

1 reference

21 September 2017

Gene C Webb

1

1 reference

21 September 2017

Arunangsu Dey

2

1 reference

21 September 2017

Jie Wang

3

1 reference

21 September 2017

Jeffrey Stein

4

1 reference

21 September 2017

Margaret Milewski

5

1 reference

21 September 2017

Donald F Steiner

6

1 reference

21 September 2017

language of work or name

English

0 references

publication date

13 May 2004

1 reference

Journal of Biological Chemistry

21 September 2017

1 reference

21 September 2017

279

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21 September 2017

30

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21 September 2017

31068-31075

1 reference

Insulin biosynthesis: evidence for a precursor

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Roles of ubiquitinylation in proteolysis and cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Signal sequences: more than just greasy peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Molecular and cellular regulation of prohormone processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Precursor convertases: an evolutionary ancient, cell-specific, combinatorial mechanism yielding diverse bioactive peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Proteolytic processing in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Enzymes required for yeast prohormone processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Furin and prohormone convertase 1/3 are major convertases in the processing of mouse pro-growth hormone-releasing hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

A covalently trapped folding intermediate of subtilisin E: spontaneous dimerization of a prosubtilisin E Ser49Cys mutant in vivo and its autoprocessing in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Regulatory roles of the P domain of the subtilisin-like prohormone convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

The proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Differential Processing of Proglucagon by the Subtilisin-like Prohormone Convertases PC2 and PC3 to Generate either Glucagon or Glucagon-like Peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Glucagon replacement via micro-osmotic pump corrects hypoglycemia and alpha-cell hyperplasia in prohormone convertase 2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: a potential mechanism for its inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Contrasting patterns of expression of transcription factors in pancreatic alpha and beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Enzymatic characterization of immunopurified prohormone convertase 2: potent inhibition by a 7B2 peptide fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

The role of the 7B2 CT peptide in the inhibition of prohormone convertase 2 in endocrine cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Expression profiling of pancreatic beta-cells: glucose regulation of secretory and metabolic pathway genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404110200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404110200

1 reference

21 September 2017

1 reference